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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. DEVELOPMENT OF A RETROFIT IN SITU THREE POINT AUDIT DEVICE FFOR TESTING OF LINEARITY AND CALIBRATION OF COMMERCIALLY AVAILABLE IN-STACK TRANSMISSOMETERS

    SBC: Eastern Technical Associates            Topic: N/A

    N/A

    SBIR Phase I 1985 Environmental Protection Agency
  2. MANY COMMERCIAL DYES HAVE A BENZIDINE BASE.

    SBC: Environmental Health Research            Topic: N/A

    MANY COMMERCIAL DYES HAVE A BENZIDINE BASE. EVIDENCE SUGGESTS A CAUSAL RELATIONSHIP BETWEEN THESE DYES AND BLADDER CANCER IN HUMANS. ROUTINE SHORT-TERM TESTS ARE INEFFICIENT FOR DETECTION OF THE BENZIDINE BASE DYES WITHOUT MODIFICATIONS. SHORT-TERM TESTS COUPLED TO ACTIVATION SYSTEMS FROM RODENT CELLS OR FRACTIONS MAY NOT BE GERMANE FOR EXTRAPOLATION TO HUMAN RISK. RECOGNIZING A NEED FOR RELEVANT ...

    SBIR Phase I 1985 Department of Health and Human Services
  3. COLORECTAL CARCINOMA IS ONE OF THE MOST PREVALENT AND LETHAL CANCERS IN THE UNITED STATES.

    SBC: Granite Diagnostics            Topic: N/A

    COLORECTAL CARCINOMA IS ONE OF THE MOST PREVALENT AND LETHAL CANCERS IN THE UNITED STATES. ACCORDING TO THE AMERICAN CANCER SOCIETY, THERE ARE 130,000 NEW CASES EACH YEAR. EARLY DIAGNOSIS IS DIFFICULT AND THERE IS NO DIAGNOSTIC TEST WITH A HIGH POSITIVE PREDICTIVE VALUE IN THE EARLY STAGES OF THE DISEASE. DEVELOPMENT OF A TEST THAT DETECTS EARLY COLORECTAL CARCINOMA WOULD SIGNIFICANTLY REDUCE MORB ...

    SBIR Phase I 1985 Department of Health and Human Services
  4. A STUDY IS PROPOSED WHICH WILL DETERMINE THE FEASIBILITY OF DEVELOPING A COMPUTER BASED MODEL FOR ADMINISTERING ASSESSMENT AND THERAPY TO MENTALLY RETARDED/DEVELOPMENTALLY DISABLED INFANTS AND CHILDREN.

    SBC: Handicapped Childrens Technolo            Topic: N/A

    A STUDY IS PROPOSED WHICH WILL DETERMINE THE FEASIBILITY OF DEVELOPING A COMPUTER BASED MODEL FOR ADMINISTERING ASSESSMENT AND THERAPY TO MENTALLY RETARDED/DEVELOPMENTALLY DISABLED INFANTS AND CHILDREN. THE PRINCIPAL AIM OF PHASE I IS TO SURVEY CURRENT TECHNOLOGIES AS THEY RELATE TO THERAPY AND PROVIDE A BASIS FOR A PHASE II RESEARCH PLAN. HARDWARE AND SOFTWARE BASED SIMULATION OF A MODEL WILL BE ...

    SBIR Phase I 1985 Department of Health and Human Services
  5. EFFICIENT, AND ECONOMICAL ALTERNATIVE ENERGY SUPPLY

    SBC: Incon Corp            Topic: N/A

    DECLINING ENERGY RESOURCES AND ENVIRONMENTAL PROBLEMS ASSOCIATED WITH THE PRODUCTION AND IMPORTATION OF FOSSIL FUELS AND THE PRODUCTION OF NUCLEAR ENERGY HAVE PRODUCED A NEED FOR RESEARCH & DEVELOPMENT OF SAFE, EFFICIENT, AND ECONOMICAL ENERGY ALTERNATIVES. SOLUTIONS MUST BE FOUND THAT CAN CONTRIBUTE A SIGNIFICANT PERCENTAGE OF THE U.S. ENERGY DEMAND AND YET BE LAND, WATER AND NUTRIENT CONSERVATIV ...

    SBIR Phase I 1985 National Science Foundation
  6. PRIMARY AROMATIC AMINES THAT WERE IMPLICATED IN BLADDER CARCINOGENESIS (BASED ON THE EPIDEMIOLOGICAL DATA WITH WORKERS IN RUBBER AND DYE INDUSTRIES) EXHIBIT SEX AND SPECIES SPECIFICITY.

    SBC: INTEGRATED LABORATORY SYSTEMS, INCORPORATED            Topic: N/A

    PRIMARY AROMATIC AMINES THAT WERE IMPLICATED IN BLADDER CARCINOGENESIS (BASED ON THE EPIDEMIOLOGICAL DATA WITH WORKERS IN RUBBER AND DYE INDUSTRIES) EXHIBIT SEX AND SPECIES SPECIFICITY. URINARY AND BLADDER CANCER IS MORE PREVALENT IN CAUCASIAN MALES. AROMATIC AMINES ARE MORE CARCINOGENIC IN DOGS AND LESS ACTIVE IN RODENTS, WHICH CORRELATES TO THE RELATIVE METABOLIC ACTIVITIES IN RESPECTIVE TISSUES ...

    SBIR Phase I 1985 Department of Health and Human Services
  7. CENTRIFUGAL FORCES-

    SBC: Jmf Enterprises, Inc.            Topic: N/A

    A PROBLEM EXISTS IN DRYING HEAT-SENSITIVE DRUGS DURING THEIR BULK CHEMICAL PRODUCTION. THE PRESENTLY AVAILABLE EQUIPMENT IS BASED ON CONDUCTION AS THE PRIMARY HEAT- TRANSFER METHOD; HOWEVER, IN DRYING HEAT-SENSITIVE CHEMICALS, THE JACKET TEMPERATURE OF CURRENT PROCESS EQUIPMENT MUST BE REDUCED TO AVOID THERMAL DEGRADATION OF THE DRUG. THE REDUCTION OF CONDUCTIVE DRIVING FORCE RESULTS IN DECREASED ...

    SBIR Phase I 1985 Department of Energy
  8. WE PROPOSE TO DEVELOP AND TEST A PORTABLE COMPUTER-BASED DATA COLLECTION/ANALYSIS AND COMPLIANCE ENHANCEMENT SYSTEM FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS (NIDDM).

    SBC: Kron Research And Consulting C            Topic: N/A

    WE PROPOSE TO DEVELOP AND TEST A PORTABLE COMPUTER-BASED DATA COLLECTION/ANALYSIS AND COMPLIANCE ENHANCEMENT SYSTEM FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS (NIDDM). THE DIACARE SYSTEM II WILL CONSIST OF THE DIACARE MONITOR (HARDWARE), WHICH COMBINES COMPUTER CAPABILITIES OF A COMMERCIALLY AVAILABLE HAND-HELD COMPUTER WITH OUR OWN REFLECTANCE PHOTOMETER GLUCOSE ANALYSIS AND DAT ...

    SBIR Phase I 1985 Department of Health and Human Services
  9. THE OVERALL GOAL OF THIS RESEARCH PROJECT IS TO DETERMINE THE FEASIBILITY OF USING CONTRAST AGENTS FOR NUCLEAR MAGNETIC RESONANCE (NMR) IMAGING.

    SBC: Mri, Inc.            Topic: N/A

    THE OVERALL GOAL OF THIS RESEARCH PROJECT IS TO DETERMINE THE FEASIBILITY OF USING CONTRAST AGENTS FOR NUCLEAR MAGNETIC RESONANCE (NMR) IMAGING. SPECIFICALLY, NITROXIDES OF VARYING STRUCTURE WILL BE SYNTHESIZED. EACH PROTOTYPE AGENT WILL BE STUDIED FROM A PHARMACOKINETIC, DISTRIBUTION, AND METABOLIC STANDPOINT. THOSE NITROXIDES WITH SUITABLE PROPERTIES WILL BE FURTHER INVESTIGATED FOR THEIR ABILIT ...

    SBIR Phase I 1985 Department of Health and Human Services
  10. IN MULTIDIMENSIONAL TRANSPORT THEORY AND SEEK SUPPORT BOTH TO DEMONSTRATE THE COMPUTATIONAL FEASIBILITY OF THIS SOLUTION AND TO EXPAND THE CLASS OF PROBLEMS CONSIDERED. THE DEVELOPED F(N) SOLUTIONS WOULD BE VERIFIED BY MONTE CARLO CALCULATIONS. THE F(N) M

    SBC: Mycosearch Inc            Topic: N/A

    N/A

    SBIR Phase II 1985 National Science Foundation

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