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SBC: PHAGEPRO, INC. Topic: NIAID
PROJECT SUMMARY Cholera is an acute and severe disease caused by the bacterium Vibrio cholerae that is spread primarily through contaminated water sources due to a lack of adequate sanitation infrastructure. The World Health Organization estimates that there are at least 3 million cases globally per year, 40 percent of which are spread through household transmission. Current prevention methods req ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: NeoView, Inc. Topic: NICHD
PROJECT SUMMARY In this Phase I Small Business Technology TransferSTTRprojecta team of researchers at Cincinnati Childrenandapos s Hospital Medical CenterCCHMCwill work with the engineering team at NeoViewIncto design and build novel body coil and incubator prototypes for aTesla Neonatal Intensive Care UnitNICUMRI systemThese components will play a central role in NeoViewandapos s neonatal MRI pro ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: KITWARE INC Topic: 105
Project Summary Morphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomy. Neurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non-local in nature and effect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomy. State-of-the-art morphometry meth ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: CHRONUS PHARMACEUTICALS, INC. Topic: NIBIB
Project Summary Abstract Bacterial infections such as those of prosthetic jointsbonesosteomyelitisand heart valvesinfective endocarditisare difficult to difficult to diagnose and treatand are a major cause of mortalitymorbidity and health care costsThe long term goal of our program is thus to develop positron emission tomographyPETradiotracers that can be used for non invasive PET imaging to detec ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: Nirvana Sciences, Inc. Topic: 400
PROJECT SUMMARY ABSTRACT Polychromatic flow cytometryFCis one of the most powerful analytical techniques used in immunologybasic researchand clinical medicineIn basic researchFC is a primary tool for understanding disease development at the cellular and subcellular levelsIn the rapidly developing field of immunotherapyFC is an indispensable tool for monitoring the effectiveness of new therapies an ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
Using advanced natural language processing to facilitate documentation of meaningful use and quality payment complianceSBC: Safermed, LLC Topic: NLM
PROJECT SUMMARY The Center for Medicare and Medicaid Services Quality Payment Program is designed to motivate healthcare providers to adhere to best practices in clinical healthcare and patient safetyUnfortunatelyextracting quality measures data from the clinical record is burdensome and as suchparticipation among clinical healthcare providers is suboptimalOur aim is to develop a system to facilit ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
A momentum-enabled treadling methodology to improve gait and enhance mobility in patients with peripheral arterial diseaseSBC: TREADWELL CORPORATION Topic: NIA
Project SummaryA significant cause of mobility impairment in the elderly is peripheral arterial diseasePADPAD results in significant functional declinereduced walking speed and distanceand lower physical activity levelsresulting in a loss of independence and impaired quality of lifeThe most effective therapy for PAD is rigorous exercisee gwalkingHowevermost PAD patients will not participate in sup ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: Applied Universal Dynamics, Corp. Topic: NIA
Project Summary Abstract This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functi ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: BERTEC CORP Topic: NIA
Falls are a significant source of early morbidity and mortality in the aging populationyet the neurologicalsensoryand motor changes that lead to increased fall risk often escape early identification and interventionVital signs are commonly used in clinical settings to assess the cardiovascular systemblood pressureheart rateimmune systembody temperatureand the respiratory systemrespiratory rateto e ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
Astrocyte activation by small-molecule ADORA3 agonists: a novel therapy for Alzheimer's diseaseSBC: ASTROCYTE PHARMACEUTICALS INC. Topic: NIA
PROJECT SUMMARY Alzheimerandapos s diseaseADis an area of significant unmet need that creates a national burden of$billion annuallyAD is the leading cause of dementiaaffectingof Americans over the age ofDemographic shifts and the age related nature of AD will soon place this disease as the costliest health care expenditure in the U Swith a projected impact of $trillion per year byCurrent therapies ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health