Award Data

DESCRIPTION (provided by applicant): Individuals with intellectual disabilities (ID) are at higher risk for abuse than the general population. Increasing numbers of people with ID are living independently in the community with both its benefits and its risks. Many individuals with ID are subjected to physical, sexual, and verbal abuse. Some of the characteristics found in people with ID - short at ...

DESCRIPTION (provided by applicant): The purpose of the proposed project, Teacher Education: Promoting Reading Readiness (TEPRR) is to give Head Start (HS) teachers access to evidence-based instructional approaches for teaching basic language and literacyskills through high quality, easily accessible, and innovative online multimedia professional development. HS focuses on serving children from lo ...

PROJECT SUMMARY The goal of this project is to develop and disseminate the Autism Parent Trainer (APT), an online platform that provides parents of children with autism coach-facilitated instruction in how to teach new behaviors, manage problem behaviors, and learn emotion regulation and stress reduction strategies. APT will use Google+ Hangouts technology as the communication medium, which al ...

DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

DESCRIPTION (provided by applicant): The longterm goal of this project is to utilize cytomegalovirus (CMV) vectors in the development of a therapeutic vaccine against herpes simplex virus 2 (HSV-2), the causative agent of genital herpes. HSV-2 is widely prevalent in the population causing recurrent genital lesions and significantly increasing the risk for other sexually transmitted diseases such a ...

DESCRIPTION (provided by applicant): Oral disease is a silent epidemic because of its prevalence and missed prevention opportunities. Evidence has established connections between oral-systemic etiologies, including the effects of periodontal disease (PD), and a range of health outcomes and co-morbidities across the lifecourse (e.g., adverse pregnancy and birth outcomes; early childhood carries; ...

DESCRIPTION (provided by applicant): A hallmark of virtually every cancer is aberrant epigenetic silencing of vital genes required for a normal cell cycle and genome stability (e.g. MLH1, BRCA1, VHL, p16, etc.). Loss of expression of these tumor suppressorgenes plays a critical role in cancer formation and growth. Thus, targeting this root cause of cancer has significant potential to treat and pot ...

PROJECT SUMMARY Cardiovascular disease (CVD) remains the number one cause of death in the U.S. Left untreated, CVD can result in the occlusion of key arteries that can precipitate a major cardiac event. Clinicians routinely correct arterial blockages mechanically using a balloon expansion of the lesioned area and placement of a metallic stent to help keep the arteries open. However, the overstretc ...

Unlike raw wood pellets, energy dense torrefied biomass pellets or briquettes share important traits with coal which make them a promising alternative clean fuel to use directly in coal plants. They are brittle (not fibrous, like raw pellets), so they can be pulverized just like coal before being fed into the coal boiler. They also have similar BTU content to coal and are water resistant, so they ...

World marine food farming production (aquaculture) is dependent on hatchery and nursery production of large quantities of high quality larvae and juvenile shellfish, shrimp and fish. Bacterial diseases, particularly vibriosis, are a major cause of mortality in hatcheries and nurseries and causelarge losses and great expense for fish and shellfish growers along the nation & #39;s coasts. Simple, sp ...