Award Data

The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

This Small Business Innovation Research (SBIR) Phase II project proposes to develop a robust, generic, front-end, bio-sampler that when combined with either a wet or dry biological detector, will result in more accurate and rapid detection of hazardous airborne biological agents. While most current systems require samples to be delivered in a fluid for analysis, emerging dry detection technologi ...

The long-term goal of this research is to develop a drug that is safe and effective against drug-resistant human immunodeficiency virus (HIV) infection. Several challenges confront current anti-HIV chemotherapy. The frequency of drug-resistant and multidrug-resistant HIV-1 is increasing. Toxicities associated with current HIV medications often result in the discontinuation of these therapies. Phys ...

DESCRIPTION (provided by applicant): The long-term objective of this research is to develop a safe and efficacious pharmacologic agent for the treatment of respiratory syncytial virus (RSV) infection. RSV is the most common cause of respiratory tract infection in infants and children in the United States. RSV associated infections result in up to 126,000 hospitalizations and more than 500 deaths i ...

Ultra-high performance multi-function RF electronics are required by the United States Department of Defense to enable next generation radar and sensor networks in response to an increasingly diverse array of threats to our military and our homeland. An elegant potential solution is that of gallium nitride (GaN) RF electronics, which has shown great promise on currently available yet foreign subs ...

The objective of this SBIR project is to develop an attached processor called an "agent based computing" module (ABC Machine) that is optimized to convert information into knowledge and enable "cognitive computing" for higher understanding. The architecture of the ABC Machine is based upon a concept called "statistical dataflow computing" and it operates in local contexts over string operators. I ...

Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

The global economy has brought about enormous opportunities in the areas of trade with developing nations. Nowhere is it more evident than in the East Asian basin. In 2002, over 12 million TEU containers where imported into the U.S. with over 60% originating in China/Hong Kong. In the same year, only 7 million TEU containers where exported from the U.S. to the rest of the world. What happened to t ...

78845S The Department of Energy desires to increase fuel efficiency by reducing vehicle weight. Carbon fiber composites offer one promising way to do this, but difficulties in building economical, consistent, high quality preforms has limited the introduction of this material. This project will to adapt a well established pulp molding technology to produce carbon fiber preforms for lightweight ...

This proposal describes the application, development and commercial scale-up of a process successfully developed under EPA contract number EP-D-04-042 for the deposition of copper and copper barrier materials such as ruthenium, titanium and other metals. This process could replace CU electroplating currently used to fill deep trenches and thin film deposition in microelectronic circuit manufactur ...