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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Title: Development of Novel Anticancer Agent to potentiate sensitivity to anti-estrogen therapy PoP: 09/19/2014 to 09/18/2016

    SBC: A&G PHARMACEUTICAL, INC.            Topic: NCI

    Not Available

    SBIR Phase II 2014 Department of Health and Human Services
  2. PHASE II, SBIR CONTRACT, N44TR-14-001,?A SCALABLE MULTI? SCALE VISUAL ANALYTICAL TOOL FOR ADVANCING TRANSLATIONAL SCIENCES: VATS?.

    SBC: Intelligent Automation, Inc.            Topic: NIDA

    Not Available

    SBIR Phase II 2014 Department of Health and Human Services
  3. IGF::OT::IGF: SBIR Phase II award mSMART: Mobile App based Personalized Solutions and Tools for Medication Adherence of Rx Pills. POP: 09/09/2014- 09/08/2016.

    SBC: Intelligent Automation, Inc.            Topic: NIDA

    Upgrade mSMART for adherence assessment and intervention delivery in a primary care practice setting. This objective includes upgrading mSMART to include the support for complex regimen and schedule, implementing mSMART on iPhone (in addition to Android),adding automated interventions, and adding staged and conditional intervention management. PUBLIC HEALTH RELEVANCE

    SBIR Phase II 2014 Department of Health and Human Services
  4. Novel method to create knockout rats using endonucleases and spermatogonial stem

    SBC: TRANSPOSAGEN BIOPHARMACEUTICALS, INC.            Topic: 200

    DESCRIPTION provided by applicant The laboratory rat is a preferred rodent model in pre clinical drug studies Their larger size facilitates procedures otherwise difficult in mice includng studies using instrumentation blood sampling and surgeries and allows for ten times the amount of tissue collection Although rats are often more suitable than mice for pharmacological toxicological phy ...

    SBIR Phase II 2014 Department of Health and Human Services
  5. Improving Accuracy and Accessibility of Early Autism Screening

    SBC: Total Child Health, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): Autism is prevalent (1 in 50 children) and impairing but early intervention has been shown to improve outcomes prompting recommendations for screening at both two year and 18 month health check-ups. Detection of autismearly is crucial but accurate screening tools have been elusive. In Phase II, a practical method of improving accuracy of M-CHAT, the most widely ...

    SBIR Phase II 2014 Department of Health and Human Services
  6. IGF::OT::IGF SBIR Topic 74- Develop a novel, low cost, blood storage system that will deliver red cells of higher quality, thereby reducing the harmful consequences of transfusion therapy. HASP is de

    SBC: NEW HEALTH SCIENCES, INC.            Topic: NHLBI

    The goal of this project is to develop a novel, low cost blood storage system that will and deliver red blood cells (RBC) of higher quality thereby reducing the harmful consequences of transfusion therapy. RBC are depleted of O2 and CO2 and stored under depleted condition. The stored RBC have shown higher efficacy and lower toxicity. The product is designed to be easily integrated into existing bl ...

    SBIR Phase II 2014 Department of Health and Human Services
  7. Infant Assessment of Early Communication Risk Factors: The ISCBS (formerly ECBS)

    SBC: PAUL H BROOKES PUBLISHING CO., INC.            Topic: NIDCD

    DESCRIPTION provided by applicant Effective early intervention depends on reliable identification of risk for communication impairments as soon as possible Established infant risk factors for communication impairments include poor turn taking gestures receptive language commenting symbolic play and speech Although these risk factors can be detected by mos and reliably predict late ...

    STTR Phase II 2014 Department of Health and Human Services
  8. Micro-targeted Computerized Alcohol Misuse Intervention System for Health Care

    SBC: RESEARCH CIRCLE ASSOCIATES            Topic: NIAAA

    DESCRIPTION provided by applicant Alcohol misuse continues to pose a major burden for public health Screening and brief intervention for alcohol misuse in primary care settings has been recommended for decades and the evidence base supporting it in primary care is robust However many primary care providers do not intervene in alcohol misuse and those that do often fail to do so systematica ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Twist-Sensor: Novel microarrays for multiplex detection of drug resistance

    SBC: SCANOGEN INC.            Topic: NIAID

    DESCRIPTION provided by applicant Drug resistance is rapidly spreading among Gram negative bacteria seriously complicating the treatment of infected patients and increasing the risk of lethal outbreaks In particular carbapenem resistant Enterobacteriaceae CRE organisms associated with high mortality rate andgt have become prevalent worldwide During of long term acute car ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Automating mosquito microdissection for a malaria PfSPZ vaccine

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION Malaria causes andgt million clinical cases and million deaths annually is responsible for andgt loss of GDP in Africa and is a serious concern for travelers and military personnel A highly effective vaccine is desperately needed and radiation attenuated Plasmodium falciparum Pf sporozoites SPZ and non attenuated PfSPZ with chloroquine chemoprophylaxis ChemoProphylax ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health

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