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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Improved AED Resuscitation with Interactive CPR Coaching

    SBC: KORONIS BIOMEDICAL TECHNOLOGIES CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): Koronis Biomedical Technology Corporation (KBT) proposes to research the use of interactive video and audio to coach responders via AEDs to perform effective chest compressions. The goal is to improve the quality of CPR delivered during treatment with an AED. New organic display technology will soon dramatically reduce the cost of applying video-quality dis ...

    SBIR Phase I 2005 Department of Health and Human Services
  2. Smart Seal Ostomy Appliance

    SBC: Korosensor.Com, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Korosensor.com, Inc. (Kl) proposes to develop a wearable ostomy appliance device with a novel built-in polymer-thick-film (PTF) sensor system that alerts the ostomy user of potential leakage problems due to seal undermining and meltdown. The ability to identify leakage problems due to an ineffective seal could reduce peristomal skin breakdown. Over 1 million os ...

    SBIR Phase II 2005 Department of Health and Human Services
  3. Rapid Bacterial Detection in Platelet Concentrates

    SBC: Medical Innovations International, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A rapid detection system can be readily developed to prevent bacterial contamination in platelet concentrates that are intended for transfusion. Bacteria contamination of platelet concentrates intended for transfusion, represents the most frequent transfusion-associated infectious risk. Bacterial contamination levels as low as 102 to 103 CFU/ml have been ass ...

    STTR Phase I 2005 Department of Health and Human Services
  4. Rapid Detection of Aspirin Resistance in Human Subjects

    SBC: Medical Innovations International, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The number of patients treated with antiplatelet agents increases annually. It is reported that over 20 million people in the U.S. alone take aspirin daily to induce some level of platelets inhibition. Clinical data shows that not all patients receive the full benefits of aspirin, and that a large patient to patient variability exists in aspirin induced platele ...

    STTR Phase I 2005 Department of Health and Human Services
  5. Electrospraying Nanoparticle Coatings on Stents

    SBC: Nanocopoeia Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR Phase I project will develop and commercialize a process for applying nanoparticle composite coatings with drugs and polymers to the surfaces of coronary artery stents. The use of performance-enhancing coatings on implantable medical devices, such as coronary artery stents, has begun to transform the device market and holds tremendous potential for ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. Stampidine: A Novel Broad-Spectrum Anti-HIV Microbicide

    SBC: PARADIGM PHARMACEUTICALS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The emergence of AIDS as a disease spread through sexual intercourse has prompted the search for new, effective, safe, and female-controlled vaginal microbicides for curbing mucosal viral transmission. Microbicides that are currently being investigated are directed mainly at preventing pregnancy as well as protection against sexually transmitted diseases. The a ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. Formulation of dosage of the anti-HIV agent, DDE113

    SBC: PARADIGM PHARMACEUTICALS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Human immunodeficiency virus (HIV) -1 the etiologic agent of AIDS is the fastest growing cause of death in men and women of reproductive age. In the absence of effective treatment as well as anti-HIV therapy or vaccine, new emphasis has been placed on the development of anti-HIV agents capable of reducing this epidemic. We have prepared a very potent anti-HIV n ...

    SBIR Phase I 2005 Department of Health and Human Services
  8. Nanoparticle Generator for Animal Inhalation Experiments

    SBC: POWERSCOPE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Objective of this research is to generate airborne fine particles around 100 nm, using high-frequency ultrasonic nebulization and subsequent spray drying. Such a particle generator would be valuable for inhalation experiments on small laboratory animals. Future applications of this technology would include generation of nano-powders of drugs for the purpose of ...

    SBIR Phase I 2005 Department of Health and Human Services
  9. Treatment of Cerebral Edema using Ventricular Therapy

    SBC: TWIN STAR MEDICAL            Topic: N/A

    DESCRIPTION (provided by applicant): Cerebral edema is associated with traumatic brain injury. The overall HYPOTHESIS of the proposed intervention is that free water removed from the brain following traumatic injury will minimize cerebral edema. Approach: The applicant proposes to complete preclinical development of an innovative catheter for the reduction of cerebral edema. The initial clinical ...

    SBIR Phase II 2005 Department of Health and Human Services
  10. Surface Modified Zirconia as Chiral Stationary Phases

    SBC: Zirchrom Separations, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our phase I work addressed one of the major current trends in HPLC - the development of materials for improved chiral chromatography. In response, we prepared two new classes of chiral stationary phases (CSPs). We prepared 10 different examples of the class wherein the chiral selector is covalently bonded to the surface of carbon-clad zirconia. Additionally, we ...

    SBIR Phase II 2005 Department of Health and Human Services

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