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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Quantitative Detection of Toxins Using Novel Compounds that Bind to Carbonhydrate Binding Sites

    SBC: OPHIDIAN PHARMACEUTICALS, INC.            Topic: N/A

    A novel set of compounds has been devised and synthesized, members of which bind to bacterial toxins with high affinity and selectivity. The compounds are covalently attached to a solid phase and can be used to selectively bind to toxins from various sources (e.g., body fluids or food extracts) for their detection and quantitation. In this proposal is described the theoretical background for the ...

    SBIR Phase I 1998 Department of DefenseArmy
  2. Volume Photorefractive Optical Interconnect Elements for C3I Applications

    SBC: OPTICOMP CORP.            Topic: N/A

    This proposal addresses a design and fabrication investigation of a volume photorefractive optical memory system. The technology supports integration into two dimensional (2D) arrays of reconfigurable optical interconnect pixels for high performance digital processing applications such as high speed telecommunications and computing. The proposed volume memory array will be integrated into the hi ...

    SBIR Phase II 1998 Department of DefenseNavy
  3. High Bandwidth Optoelectronic Packaging Technology for a Processor-Memory I/O

    SBC: OPTICOMP CORP.            Topic: N/A

    The primary goal of this program is to develop intelligent software mechnaisms which enhance information discovery using a high capacity, scalable, optoelectronic information architecture. By exploiting a high performance optoelectronic computing (HPOC) module platform as a data "processing engine", innovative software mechanisms will be investigated which can manipulate data/knowledge ...

    SBIR Phase II 1998 Department of DefenseMissile Defense Agency
  4. High-Speed Peizoelectric Positioner for Precision Machining

    SBC: PIEZOMAX TECHNOLOGIES, INC.            Topic: N/A

    This Small Business Innovation Research Phase I project will investigate the feasibility of an innovative concept in high-speed closed-loop feedback control systems for piezoelectric positioners used in precision manufacturing. There is considerable use, and considerably greater potential for use, of piezoelectric actuators, positioners, and sensors in precision manufacturing, and specifical ...

    SBIR Phase II 1998 Department of DefenseNavy
  5. Advanced Piezoelectric-Positioner Controller for High-Speed Scanning Probe Microscopy

    SBC: PIEZOMAX TECHNOLOGIES, INC.            Topic: N/A

    This SBIR Phase I project will investigate the feasibility of an improved control strategy for piezoelectric positioners used in scanned-probe microscopes (SPMs) to increase their speed and reliability for nanocharacterization. Rapid nanocharacterization requires fast motion of the scanned piezo probe with sub-Angstrom vertical resolution and with frequent rapid changes in its axial position. Se ...

    SBIR Phase II 1998 Department of DefenseDefense Advanced Research Projects Agency
  6. The Design and Synthsis of Orally Active Inhibitors of Botulinum Toxin Metalloproteases

    SBC: PROMEGA CORP.            Topic: N/A

    This proposal describes strategies to synthesize potent inhibitors of botulinum neurotoxin metalloproteases. These metalloproteases [BoTx protease] have been shown to be the molecular effectors of the paralytic effects of these toxins. Mechanism-based drug design will be applied to develop peptide-derived inhibitors of these proteases. At the same time, experiments to develop non-peptide templa ...

    SBIR Phase II 1998 Department of DefenseArmy
  7. The Design and Construction of Botulinum Toxin Drug Delivery Vehicles

    SBC: PROMEGA CORP.            Topic: N/A

    This proposal describes strategies to develop a neural cell specific delivery vehicle system which utilizes the target specificity of the botulinum toxin family to provide a generic platform for the delivery of drugs to the neuronal cytosol. Using a multi-disciplinary approach, we will construct and evaluate a non-toxic form of botulinum neurotoxin (BoNT) for use as a neural cell specific delivery ...

    SBIR Phase I 1998 Department of DefenseArmy
  8. Radio Frequency (RF) Plane Wave Generator

    SBC: Quick Reaction Corporation            Topic: N/A

    QRC submits this proposal in response to SBIR AF98-286 for a Plane Wave generator. The plane wave generator is required to generate a free space RF wave installed in the Benefield Anechoic Facility (BAF) to evaluate the various electromagnetic systems installed on the aircraft systems such as the B1B, F16, and C17. The generator must cover a wide frequency band in order to test the many differen ...

    SBIR Phase I 1998 Department of DefenseAir Force
  9. Advanced Integrated Tribology System

    SBC: SURFACES RESEARCH & APPLICATIONS, INCO            Topic: N/A

    The objective of this program is to develop an integrated tribology system for advanced low heat rejection (LHR) diesel engines. The system will consist of a substantially improved high-temperature liquid lubricant, for long life under severe conditions; improved compatible engine tribomaterials; and an on-board sensor arrays for direct monitoring of engine oil condition. Surfaces Research lubri ...

    SBIR Phase II 1998 Department of DefenseArmy
  10. Synergistic Liquid-Solid Lubricant System

    SBC: SURFACES RESEARCH & APPLICATIONS, INCO            Topic: N/A

    The objective of this program is to develop an advanced tribology system for the next generation of high-output, low heat rejection (LHR) diesel engines. Engines for the U.S. Army Future Combat System will operate at significantly higher temperatures than today's prototype LHR engines. Surfaces Research proposes a program to develop wear-resistant coatings and engine oils that each contain solid ...

    SBIR Phase I 1998 Department of DefenseArmy

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