Award Data

THE WORLDWIDE POTENTIAL MARKET FOR LIGAMENT AND TENDON IMPLANTS IS IN EXCESS OF 100,000 UNITS ANNUALLY. THE CURRENTLY AVAILABLE PROSTHETIC IMPLANTS ARE CLINICALLY UNSATISFACTORY AND AUTOLOGOUS GRAFTS MAY COMPROMISE THE SITE OF TISSUE ORIGIN. THE LONG TERM OBJECTIVE OF THIS PROJECT IS TO DEVELOP METHODS FOR PROCUREMENT, TRANSPORTATION, PRESERVATION, AND TRANSPLANTATION OF ALLOGRAFT LIGAMENTS AND TE ...

THE PURPOSE OF THIS RESEARCH IS PRODUCTION AND TESTING OF A NEEDLE-IMPLANTABLE DEVICE FOR ESTIMATING LONG-TERM TISSUE AVAILABILITY OF THE HORMONE CORTICOSTERONE IN RATS. THIS WORK CONTRIBUTES TO THE LONG-TERM GOAL OF DEVELOPING A SIMILAR DEVICE FOR MEASUREMENT OF THE TISSUE AVAILABILITY OFA BROAD RANGE OF COMPOUNDS IN BOTH RESEARCH AND MEDICAL SETTINGS. THE DEVICE OPERATES ON THE DIFFUSION-SINK PR ...

THE PROPOSED RESEARCH WILL TEST THE APPLICABILITY OF A NEW METHOD FOR TIME-INTEGRATING MEASUREMENT OF THE TISSUE AVAILABILITY OF HORMONES, TO THE OVARIAN HORMONE ESTRADIOL. THE NEW METHOD USES AN ULTRAMINIATURE DEVICE, INSTALLED IN THE MOUTH OF A SUBJECT, TO CONTINUOUSLY ACCUMULATE HORMONES FROM THE SALIVA. THE RATE OF ACCUMULATION AT ANY MOMENT DIRECTLY REFLECTS THE AVAILABILITY OF THE HORMONE TO ...

IT IS PROPOSED TO DEVELOP A PULSED HYDROGEN FLUORIDE (HF) CHEMICAL LASER SYSTEM THAT IS SPECIFICALLY DESIGNED FOR USE IN CORNEAL MICROSURGERY. LASER PARAMETERS SUCH AS PULSE ENERGY, PULSE DURATION, BEAM QUALITY, AND OUTPUT SPECTRA WILL BE OPTIMIZED FOR APPLICATION IN CORNEAL MICROSURGERY. ISSUES RELATED TO USE IN A MEDICAL ENVIRONMENT, SUCH AS LASER SIZE AND PACKAGING, FUELS AND EXHAUST HANDLING, ...

N/A

PROPOSED IS A FAMILY-CENTERED YOUTH SUBSTANCE ABUSE PREVENTION PROGRAM (FC-YSAPP). THE PROJECT WILL DEVELOP, COMPREHENSIVELY FIELD TEST AND REFINE THE PROGRAM FOR THE MARKET. THE PROGRAM IS DESIGNED FOR USE BY COMMUNITY ORGANIZATIONS FOR FAMILIES WITH PREADOLESCENTS AT RISK OF SUBSTANCE USE/ABUSE IN AN URBAN SETTING. FC-YSAPP WILL BE DEVELOPED AND TESTED FOR EFFECTIVENESS FOR MINORITY/ETHNIC AS WE ...

IN COLORADO, MANY OF THE 260,000 OLDER ADULTS WHO ARE MEDICARE BENEFICARIES SUFFER FROM A LACK OF KNOWLEDGE AND UNDERSTANDING OF THE OPTIONS AND CONSEQUENCES OF SPECIFIC HEALTH CARE PLANS. AS CAPITATION SYSTEMS FOR PAYMENT OF HEALTH CARE SYSTEMS GROW, AND THE CATASTROPHIC HEALTH INSURANCE PROGRAM IS APPROVED. THERE IS AN INCREASING NEED FOR OLDER ADULTS TO UNDERSTAND THE COVERAGES OF THEIR HEALTH ...

THE SUCCESSFUL PRODUCTION OF NEURAL PROSTHESES, ESPECIALLY THOSE FOR USE IN CORTICAL AREAS, REQUIRES THE USE OF VERY THIN AND HIGHLY EFFICIENT BIOCOMPATIBLE FIBER ELECTRODES WHICH CAN CONTINUE TO WORK RELIABLY DURING LONGTERM RESIDENCE IN THE BODY. IMPROVED PERFORMANCE OF THESE ELECTRODES IS EXPECTED IF THEY CAN BE COATED WITH A HIGHLY ADHERENT LAYER OF IRIDIUM OXIDE. SUCH A COATING IS BIOCOMPATIB ...

NEW NASA SATELLITE REMOTE SENSING PROGRAMS SUCH AS TRMM, WHICH INTEND TO MEASURE GLOBAL PRECIPITATION, REQUIRE "GROUND TRUTH" CALIBRATION. PRECIPITATION MEASUREMENT IS ESPECIALLY DIFFICULT FROM SHIPS AT SEA, WHICH ARE THE PRIMARY "SEA TRUTH" AVAILABLE OVER MOST OF THE EARTH'S SURFACE. CONVENTIONAL GAGES ARE UNSUITED TO MARINE PLATFORMS. IF SUCCESSFUL, THIS RESEARCH WILL RESULT IN A PRACTICAL AND I ...

A NON-INTRUSIVE FLOW MEASUREMENT SYSTEM IS PROPOSED FOR SMALL DIAMETER, LOW FLOW RATE, AND LOW PRESSURE DIFFERENTIALTHERMAL CONTROL FLUID SYSTEMS. THE PROPOSED TECHNIQUE UTILIZES A CW DIODE BASED LASER DOPPLER VELOCIMETER (LDV) WHICH CAPTURES SCATTERED RADIATIONFROM MINUTE (