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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. WEB-BASED CORE COMPETENCY TRAINING FOR COALITIONS

    SBC: COMMUNITY SYSTEMS GROUP, INC.            Topic: N/A

    The long-term objective ofthis project is to create a scalable, affordable training and support system for comunity anti-drug coalitions. While training on various elecments of coalition effectiveness is available, market studies (see below) show that coalitions find this training to be inconvenient, expensive, incomplete, piecemeal and unconnected to post-training support. Therefore, coalitions l ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Proof-of-Concept for Card-based CD4 Cell Counting

    SBC: E.I. SPECTRA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this proposed research is to develop a simple, inexpensive point-of-care device that will perform absolute and percent CD4+ T cell counts from whole blood. This will be accomplished by adaptin g and testing a novel hybrid approach to microfluidic sample preparation and analysis. One-time use thin-film laminated microfluidic cassette ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. System for generation of frozen-hydrated samples using the Focused Ion Beam

    SBC: HUMMINGBIRD PRECISION MACHINE CO.            Topic: N/A

    Project Summary The long term objective of our application is to develop hardware and procedures that will allow researchers to better understand the function of the cell. Our specific aim is to provide a system that will allow researches to better prepare frozen hydrated specimens for study via tomographic reconstruction in the transmission electron microscope(TEM) Current methods of preparing f ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Dock and Lock: Novel Protein Engineering

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase II application is the commercial development of CEA-ImmunoPET for breast cancer imaging. CEA-ImmunoPET is a two-component product system comprising TF2, a trivalent, bispecific, anti-CEA x an ti-HSG constructs made by the Dock and Lock (DNL) method, and 68Ga-IMP288, a DOTA- derivatized di-HSG peptide radiolabeled with 68Ga. In the Ph ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. MAb-based targeted chemotherapy of lung cancer

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Lung cancer is one of the most common malignancies worldwide, and the 5-year survival rate is only 15%. As existing therapies do not significantly increase survival rate, there is an urgent need to develop newer therapi es that can augment the existing treatments. The goal of the proposed work is to produce a safe and effective targeted chemotherapy for the tre ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. An anti-CD74 MAb-drug conjugate for B-cell malignancies

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this work is to develop an antibody-doxorubicin conjugate for the targeted therapy of B-cell cancers that express the CD74 antigen. The Phase II project will focus on advancing this product for multiple myel oma, a common plasma cell malignancy that is incurable at this time. The average 5-year survival rate for these patients is only 30%, and there ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Monitoring System For Vector-Based Influenza Vaccine

    SBC: INDEVR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II Advanced Technology SBIR [PA-06-134] proposal is in response to NIAID's Notice of High-Priority Influenza Research Areas [NOT-AI-05-013]. In order to provide health officials with the tools required to eff iciently combat a pandemic strain of influenza, it is essential that rapid and cost-effective methods for vaccine production be developed. The ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced Endoscopic Display Technology

    SBC: InterScience, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Endoscopic visualization is of primary importance for minimally invasive surgery (MIS) procedures and various clinical diagnoses. However, a known limitation of current endoscopic imaging technology for some procedures and applications is the limited field of view. For better comprehension of the operating field, it is highly desirable and in some procedures c ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Anti-inflammatory Nicotinic Agonists for Therapy of Ulcerative Colitis

    SBC: InterScience, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary/Abstract The proposed fast track effort is aimed at integrating InterScience's C-View imaging technology, capable of providing an uninhibited 240 degree vertical and 360 degree panoramic field of view to a single image plane, with distal sensor technology, an innovative illumination scheme and semi-rigid endoscope packaging. The ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Novel PDE Inhibitors for Treatment of Cognitive Dysfunction in Schizophrenia

    SBC: INTRA-CELLULAR THERAPIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is submitted as a Phase II SBIR application, pursuant to our existing Phase I grant, which was funded in response to the NIMH Program Announcement #PA-02-027 entitled: "Pharmacological agents and drugs for mental disorders". The development of new pharmaceuticals for neuropsychiatric disorders is limited by the lack of rapid and effective methods ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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