Award Data

A Multimodal Acoustic Tool for Inline Pipe Inspection 3/19/2018 The US energy transport pipeline system is a longstanding distribution network with most of its still standing pipes being installed between the 1950s–1970s. Due to degradation mechanisms, such as embrittlement, capable of causing a two-fold reduction in fracture toughness, pipe rupture is a major risk. Current nondestructive ins ...

Combined Cleaning and Guided Wave Inspection System for Hazardous Liquid Pipelines 3/20/2018 For this SBIR we will develop a machine vision system which uses onboard standard-resolution cameras in vehicles to identify and read barcode signs on the roadside. The proposed approach could provide a low-cost solution that make connected and automated vehicle (CAV) technology viable for rural areas ...

PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

PROJECT SUMMARY Up toof treated women with early stage breast cancer will suffer from local recurrences on the chest wallRCWTreatment of local recurrences is problematic and surgery provides only ayear control rateRadiation therapy is a preferred optionbut efficacy is low for larger lesionsandgtcm diameterand additional rounds of radiation therapy are associated with other long term risks due to c ...

Project SummaryBone growth is critical to a favorable prognosis in thebreast cancer patients that have skeletal metastasesor approximatelypatients per year in the USLytic lesionsor voids in the boneresult from local bone destruction caused by tumor cell directedosteoclastic bone re absorption and lead to pathologic fracture and increased patient morbiditySurgical intervention is necessary to preve ...

Project Summary Abstract This proposal seeks to develop and validate a novel technology for detecting malignant cells in biospecimen samples of oral and oropharyngeal cancerThis technology will allow screeningdiagnosisand quantification at higher precision and lower cost than what is currently availableIn the USboth the incidence and societal impact of oropharyngeal cancer are increasingdespite th ...

Project Summary Mucopolysaccharidosis type IMPS Iis an autosomal recessive storage disease caused by the absence ofL iduronidaseIDUAresulting in systemic accumulation of glycosaminoglycanGAGstorage materialshepatosplenomegalyskeletal dysplasiascardiopulmonary obstructionprogressive neurologic impairment and death by ageMPS I is currently treated by enzyme replacement therapy and by allogeneic hema ...

PROJECT SUMMARY Dental caries are the most prevalent chronic disease worldwideIn factin most industrialized countries nearlyof the adult population andof school aged children are affectedDetection of non cavitated lesions which progress slowly enable clinicians to use non operative preventive strategies to arrest their growthMoreovercurrent techniques suffer from high false positive detection rate ...

This proposal offers a new approach to stabilizing the very high capacity Si to use for lithium ion anodes - the use of a LiSi alloy rather than only Si. By starting with a silicon alloy instead of pure silicon, the initial structure is already in a stable expanded state. Mathematically stresses encountered on charging and discharging are reduced when the silicon is partially lithiated. It has bee ...

Abstract Summary Liver disease claims overlives every year in the U SaloneUnfortunatelythere are no dialysis or left ventricular assist device equivalents for liver failure and a liver transplant is the only treatmentYet thousands of potentially transplantable livers are discarded every year due to limitations in organ preservation timeswhich are on the order of hoursThe broad objective of this pr ...