Award Data

Toyon Research Corporation in collaboration with Duke University is proposing to leverage our successful Phase I analysis, preliminary radar design, simulation, algorithm development and experimentation, to demonstrate a compact, high resolution MIMO radar operating in Ka-band for small unmanned system detection, classification and tracking. Our proposed system is capable of detecting -20dBsm aeri ...

A single, ground-based, passive, standoff chemical agent vapor sensor cannot map a chemical vapor cloud because passive sensors only measure direction and not range to vapor clouds. It is not always possible, especially for a ground vehicle mounted standoff sensor, to have additional ground-based sensors at favorable vantage points to assist in threat mapping. The objective of the proposed effort ...

Applied Novel Devices (AND) is commercializing an innovative power MOSFET technology platform (called ANDFET) that brings in several unique GaN-like performance benefits to Si power devices at a fraction of the cost.  As part of this sequential proposal, we propose to increase the technical maturity level and manufacturing readiness level from TRL/MRL level 6 to level 8.  During this project, AN ...

Machine learning algorithms have demonstrated performance on par with or superior to human analysts on large datasets when sufficient training data is available.  For military applications obtaining sufficient, truthed data is always a challenge.  Three approaches have been used for measured data collections to support sensor exploitation programs: coordinated collections, turntable measurements ...

Project Summary: Over 1.5 million Americans suffer from type 1 diabetes (T1D), an autoimmune disorder involving insulin, a hormone that is essential for blood glucose regulation and overall energy metabolism. When first diagnosed with T1D, it is estimated that the patient’s insulin has been reduced by 70-90%. By this point, the immune system has already targeted and destroyed a vast majority of ...

Abstract Out-of-hospital cardiac arrest affects over 350,000 people in the U.S. annually, but only 10.8% survive. Bystander cardiopulmonary resuscitation (CPR) improves survival, but rates of training in the U.S. are low. It is recently required by law in 39 U.S. states that high school students learn CPR. However, current methods of teaching CPR use outdated pedagogical strategies and expensive d ...

Determining physical properties such as density, strength and stiffness of structures made from geomaterials typically requires destructive testing for direct measurements or inference from non-destructive measurements when the composition is unknown. These methods also require physical proximity to the structures being evaluated, a luxury that is not always available or safe. A non-destructive me ...

ABSTRACT Type-1 Diabetes Mellitus (T1DM) affects 1.25 million patients in US with 40,000 new patients annually. Lifespan is shortened 11-13 years, due to kidney and heart disease. Tight glucose control reduces microvascular complications and adverse cardiovascular events. Insulin therapy is essential for such patients, but has shortcomings: a) only 1 in 3 patients achieve targeted glucose control ...

Summary Our goal is to commercialize interstitial chemo-phototherapy (I-CPT) as a new therapeutic option for locally advanced liver cancers. Doxorubicin (Dox) can be actively loaded into long circulating, serum-stable, porphyrin- phospholipid (PoP) liposomes and be released with 665-nm laser light (PhotoDox). This approach leads to vastly enhanced drug accumulation in irradiated tissues, resulting ...

PROJECT SUMMARYMultiple Sclerosis (MS) is the most common neurological disease of early adulthood and is mediated by autoimmune mechanisms that lead to demyelination and neuronal damage in the central nervous system, resulting in progressive neurological dysfunction. Up to date, there is no cure for this devastating disease and current available treatments focus on preventing future immunological ...