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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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High Integrity and High Yield DNA Extraction Using a Nanostructured Surface
SBC: Circulomics Inc. Topic: NIGMSHigh Integrity and High Yield DNA Extraction Using a Nanostructured Surface DNA/RNA extraction is a critical first step that underpins nearly all of molecular biology. Phenol/chloroform precipitation remains the gold standard when the highest DNA integrity, yield, and purity are needed. However, the significant manual skill and dexterity required makes this method labor intensive, low throughput, ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Riboswitch Based Methyltransferase HTS Assay for Epigenetic Drug Discovery
SBC: Bellbrook Labs, LLC Topic: NIGMSDESCRIPTION (provided by applicant): Epigenetic regulation of gene expression via methylation has been implicated in diverse diseases including cancer, diabetes and inflammation, and high throughput screening for histone methyltransferase (HMT) inhibitorsis an area of intense drug discovery effort. However, there are significant shortcomings with existing HMT enzyme assay methods, and these are sl ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
An Efficient Fully 3-Dimensional Cell Migration Assay
SBC: Platypus Technologies, LLC Topic: NIGMSDESCRIPTION (provided by applicant): The goal of this SBIR project is to design and develop an efficient, physiologically relevant and cost-effective 96-well 3-D Cell Migration Assay that is compatible with mid-high throughput/high content assay platforms.Due to its importance in cancer and associated metastatic processes, cell migration is intensively studied and in vitro cell migration assays a ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Recombinant antibodies for antibody arrays
SBC: MESO SCALE DIAGNOSTICS, LLC Topic: NIGMSDESCRIPTION (provided by applicant): We propose to develop a rapid, low cost and high-throughput method for generating recombinant engineered antibodies with improved properties for proteomic and immunoassay applications. Engineered antibody constructs such as recombinant Fab fragments and chimeric antibodies will be generated and expressed by directly modifying the antibody genes in antibody-pro ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Novel APCI source
SBC: MASSTECH, INC. Topic: NIGMSDESCRIPTION (provided by applicant): Significant increase in the efficiency and speed of atmospheric pressure chemical ionization (APCI) in tandem mass spectrometry (MS/MS) will have a profound impact on its applications to the entire analytical field of characterization of drugs, metabolites, lipids, steroids, etc. A broad applicability of APCI-based MS analysis makes it a unique analytical tool ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Lessons from Nature: Antifreeze Glycolipids for Cryopreservation of Mammalian Cel
SBC: Cell & Tissue Systems, Inc. Topic: NIGMSDESCRIPTION (provided by applicant): Storage of cells for many researchers simply involves addition of 10% DMSO or similar cryoprotectants to cells in suspension, putting them in cryovials and slow cooling to subzero temperaturesf and storage in a mechanical or nitrogen cooled freezer or dewar. As long as viable cells are present upon thawing, cell yield may be a secondary consideration due to the ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Selectively Absorbable Surgical Mesh for Hernia Repair
SBC: POLY-MED, INC. Topic: NIGMSDESCRIPTION (provided by applicant): Hernia repair is one of the most frequently performed surgical operations in the United States with approximately 800,000 procedures performed annually. The vast majority of these repairs employ a tension- free repairtechnique which involves the use of synthetic surgical meshes. Existing mesh technology is designed to be of high strength to produce a perceive ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
New Tools for Structural Variation Analysis, De Novo Assembly and Closing of Complex Genomes
SBC: LUCIGEN CORPORATION Topic: NHGRIDESCRIPTION (provided by applicant): Next-generation sequencing (NGS) platforms are fundamentally altering genetic and genomic research by providing massive amounts of data in a low-cost, high-throughput format. The main drawback of existing technologies is the short sequence read lengths they produce. Existing library prep methods are also constrained in producing short inserts of only a few kb. ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of a Smartphone Mobile App for HIV Care and Prevention in YMSM
SBC: CAPITAL TECHNOLOGY INFORMATION SERVICES, Topic: NIMHDDESCRIPTION (provided by applicant): Over the past decade, the number of people living with HIV has increased while the annual number of new infections has remained relatively stable. Gay, bisexual, and other men who have sex with men (MSM), particularly young black/African American MSM (YBMSM), are disproportionately impacted. The number of new cases among people aged 13-29 years increased by 21% ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of novel, biophysically designed fluids for swallowing disorders
SBC: Swallow Solutions, LLC Topic: NINRDESCRIPTION (provided by applicant): Swallowing disorders, known as dysphagia, are associated with increased mortality and morbidity, including malnutrition, dehydration, pulmonary complications, and reduced quality of life. More than 18 million adults (and millions more children) suffer from dysphagia. Dysphagia commonly causes thin liquids (e.g., water, coffee) to be aspirated or misdirected int ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health