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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Evaluation of Novel Cyclophilin D Inhibitors for Mitochondrial Disease Therapy
SBC: SCYNEXIS, INC. Topic: NIAMSDESCRIPTION (provided by applicant): Myopathies and other clinical disorders arising from genetic abnormalities of the mitochondrial respiratory chain collectively affect as many as 1 in 8000 individuals, representing in aggregate a significant disease burden, even though the specific underlying genetic lesions are each quite rare. Despite the need for therapeutic strategies to prevent or slow the ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Lessons from Nature: Antifreeze Glycolipids for Cryopreservation of Mammalian Cel
SBC: Cell & Tissue Systems, Inc. Topic: NIGMSDESCRIPTION (provided by applicant): Storage of cells for many researchers simply involves addition of 10% DMSO or similar cryoprotectants to cells in suspension, putting them in cryovials and slow cooling to subzero temperaturesf and storage in a mechanical or nitrogen cooled freezer or dewar. As long as viable cells are present upon thawing, cell yield may be a secondary consideration due to the ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Choroidal Blood Flow Imaging with Spectral Domain OCT
SBC: BIOPTIGEN, INC. Topic: NEIDESCRIPTION (provided by applicant): Ophthalmic vascular diseases impact millions of Americans. Age-related macular degeneration and diabetic retinopathy are the two major diseases with a well- known vascular factor. The role of the vascular system in glaucoma and retinopathy of prematurity is more insidious. The vascular theory of glaucoma suggests that the blood supply to the eye is a contributo ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
R3: A Smart Attachment for Improving Adherence and Usage of Metered Dose Inhalers
SBC: Cognita Labs, LLC Topic: NIDADESCRIPTION (provided by applicant): Respiratory illnesses continue to be on the rise1-4, in particular, COPD alone impacts nearly 210 million globally 6. Metered Dose Inhaler (MDI) is the most common mechanism to deliver medicine, and is used by the patients for both maintenance and rescue medications. It is well established that regular use of the medications minimizes long-term damage to the lu ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Clinical development of 18F PET tracer for imaging VEGF receptors
SBC: SIBTECH, INC. Topic: NCIThe overall goal of this collaborative Fast-Track project is clinical development of a novel 18F PET tracer for molecular imaging of receptors for vascular endothelial growth factor (VEGFR). This receptor is the major anti-angiogenic drug target in oncology patients. Critically, VEGFR prevalence decreases when VEGF/VEGFR anti-angiogenic inhibitors work , and increases when these drugs stop worki ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Ovarian cancer using novel nanoparticle formulations
SBC: KIROMIC BIOPHARMA INC Topic: 102DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of an information-rich assay for C9ORF72 as a test for ALS and FTD
SBC: ASURAGEN, INC. Topic: NINDSDESCRIPTION (provided by applicant): The long term goal of this project is to develop, validate, and commercialize an assay to improve screening of C9ORF72, a gene on chromosome 9 that is linked to frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Expansions of a guanine and cytosine rich hexanucleotide repeat (GGGGCC) in the non-coding region of C9ORF72 is associated with up ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
System for Multiplex Protein:Protein Interaction Studies Modeled with Antibodies
SBC: AXIOMX INC Topic: NIGMSDESCRIPTION (provided by applicant): The overarching goal of Phase I is to produce a method that will generate, identify and clone a catalog of protein-protein interactions in a single rapid experiment. In this proposal we will model the technology using antibody-antigen interactions. Recombinant antibody libraries against a proteome could be produced prior to any need, and then desired affinity r ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Human Induced Pluripotent Stem Cell-Derived Beta-Cells for Drug and Toxicity Testing
SBC: Regenerative Medical Solutions Inc Topic: NIDDK? DESCRIPTION (provided by applicant): Diabetes represents one of the most serious health crises worldwide. It is estimated by the American Diabetes Association that one person is diagnosed with diabetes every 17 seconds, while the International Diabetes Federation states that one person dies every seven seconds from diabetes. Diabetes growth continues to skyrocket, with over 382 million cases ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Wireless Vagal Nerve Stimulation System for Treating Atrial Fibrillation
SBC: ROSELLINI SCIENTIFIC, LLC Topic: NHLBIDESCRIPTION (provided by applicant): Atrial fibrillation (AF) is the most common cardiac arrhythmia, and is associated with substantial risk of morbidity and mortality. AF currently affects more than 2.5 million Americans and the affected population is steadily growing with our aging society. AF independently increases the risk of stroke by 4- to 5-fold, is an independent risk factor for stroke re ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health