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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Investigation of a nanoparticle albumin-bound mTOR inhibitor, nab-rapamycin for t
SBC: AADI, LLC Topic: 102DESCRIPTION provided by applicant In it is estimated that there will be new bladder cancer cases in the United States resulting in deaths Most cases present with nonmuscle invasive bladder cancer NMIBC Intravesical bacillus Calmette Guerin BCG which elicits a nonspecific local immune response is considered the standard first line treatment However ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Protein Sequencing Tools for Biological Therapeutics
SBC: PROTEIN METRICS INC Topic: 400DESCRIPTION provided by applicant Mass spectrometry has become a method of choice for identifying and characterizing small quantities of proteins in complex mixtures However the ability to perform the identification in a high throughput fashion has depended on the availability of high quality protein sequence databases This means that proteins from organisms with unsequenced or poorly sequen ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P
SBC: Anasys Instruments Corp. Topic: 300DESCRIPTION provided by applicant Anasys Instruments and Prof Lynne Taylor of Purdue propose to develop nanoscale chemical characterization capabilities for drug formulation research This project will build on successful Phase I research demonstrating feasibility of atomic force microscope based infrared spectroscopy AFM IR in pharmaceutical applications This Phase II research will advance ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Discovery of Oligodendrocyte Stimulators
SBC: Medosome Biotec, LLC Topic: 101DESCRIPTION provided by applicant Up to of low birth weight preterm infants manifest some form of periventricular white matter injury PWMI making it the most common form of brain injury affecting premature infants In the US infants per year are born at risk for PWMI and about children per year will develop PWMI World wide infants will be born each year at ri ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers
SBC: AGILE HEALTH INC Topic: NIMHDDESCRIPTION provided by applicant Latinos Kick Buts Mobile Engagement and Cessation Support for Latino Smokers Latinos are less likely than non Hispanic whites to have access to health to have knowledge of existing smoking cessation resources to receive advice to stop smoking and to participate in smoking cessation programs Mobile technologies can dramatically enhance the reach of effectiv ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of a Gene and Oligonucleotide Delivery System
SBC: MOLECULAR EXPRESS, INC Topic: NCATSDESCRIPTION provided by applicant The knockdown of targeted genes by anti sense oligonucleotides ODNS and genetic medicines collectively G MEDS holds promise for a variety of therapies The delivery of effective quantities of ODNS to specific cells however has proved to be challenging We propose here a novel approach to ODN delivery that involves enveloped virus like particles EVLPs ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Dysbiotic Rebalancing with S. epidermidis Fermentation in Acne Vulgaris
SBC: Surface Bioadvances, Inc. Topic: NIAMSDESCRIPTION provided by applicant Dysbiosis refers to a condition with microbial imbalances within the human microbiome Yogurts are the best examples of using fermenting gut bacteria to rebalance the gut dysbiosis Our results demonstrate for the first time that Staphylococcus epidermidis S epidermidis a commensal bacterium of the human skin functions as a probiotic microorganism that em ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Therapeutic Antibodies for Biofilm Infections
SBC: TRELLIS BIOSCIENCE, INC. Topic: NIAIDDESCRIPTION provided by applicant About of serious bacterial infections are biofilm mediated Not only do biofilms provide an anchor and physical protection for bacterial cells but the physiology and genetic programming of bacteria also shifts between the planktonic free floating and sessile stationary states Most notably antibiotic sensitivity differs betwen the two states with ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Improving the therapeutic efficacy of a lead vaccine against plague using a novel adjuvant system
SBC: FasCure Therapeutics LLC Topic: NIAIDDESCRIPTION provided by applicant FasCure Therapeutics focuses on the development of adjuvant systems to generate prophylactic and therapeutic immune responses The major objective of this Phase STTR proposal is to reformulate a lead plague subunit vaccine with a novel adjuvant system to improve its protective efficacy Yersinia pestis is the causative agent of bubonic and pneumonic plague ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Novel Activin A Antagonists for Treatment of Osteoporosis
SBC: ABREOS BIOSCIENCES, INC. Topic: NIAMSDESCRIPTION provided by applicant Bone loss and fragility from osteoporosis afflict more than million people worldwide including at least million Americans Current osteoporosis treatments are significantly deficient most fail to reverse bone loss and or have adverse effects that prohibit their long term use New therapeutic approaches are urgently needed Recently the TGF family li ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health