Award Data

A reliable, low-cost, low-power, adjustable, optical-correction technology for the Avon M50 respirator is proposed that is capable of deliveringthe eye relief needed by users needing visual correction with +/ 9 diopter correction in less than 100 ms, while maintaining a wide gaze angle.To achieve the application requirements, a series of freeform GRIN Alvarez lenses will be designed, fabricated, a ...

As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological, and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. In addition to confirming an initial CBR detection, M2FM will aid in characterizing the threat scenario by estimating ...

This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...

We propose a high performance, cost-effective, universal Digital Assay Solutions platform with Mobile Readers, Assay Development and Calibration Software, and HIPAA-compliant cloud services for global health and defense applications. In Phase II project, we have developed the first generation product family receiving considerable interest from the assay manufacturers, government organizations and ...

Medics will use End User Devices (EUD) to capture electronic medical data on casualties treated at the point of injury and during enroute casualty evacuation. In order to facilitate the input of medical information, medics will use the Voice-to-Text techn

To address the DHP need for a novel self-propelled tick collection device that is capable of operating in diverse habitats under various environmental conditions, Physical Optics Corporation (POC) proposes to develop a new Multifunctional Automated Tick-Collection Rover (MATR) based on a novel system design, and mature COTS and in-house components. MATR is a configurable lightweight autonomous all ...

Nowhere are limitations in the Electronic Health Record (EHR) more evident than within the first critical periods of care (the golden hour)from injury presentation, primary survey, stabilization, secondary survey, transportation, triage, and medical facility admission. Despite the commencement of clinical care, EHR limitations prevent much of this information from being captured and shared. In mil ...

To address the CBDs need for a signal processing system designed to analyze and fuse data collected from chemical and biological sensors, Physical Optics Corporation (POC) proposes to further develop the Wavelet-Based Approach for Signal Processing and Analysis (WASP). WASP is based on novel application of Wavelet-based analysis to multimodal, multidimensional data available from a wide variety of ...

There is a lack of quantitative tools to accurately map tissue viability in a rapid and quantitative manner so a surgeon can properly excise tissue prior to grafting. Spatial Frequency Domain Imaging (SFDI) is an optical method that has been shown to be a reliable method for physiology assessment - particularly for burn depth. SFDI measures of tissue structure (scattering) and function (hemoglobi ...

The goal of this STTR effort is to design a portable, multimodal, non-contact imaging system for burn depth diagnosis and tracking of wound healing. UC and Vanderbilt University will build upon our previous efforts demonstrated via porcine model studies to combine results from structural B-mode optical coherence tomography (OCT) images and functional data (pulse speckle imaging- PSI) to classify d ...