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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Combo beta-blockers & beta2-agonists for asthma therapy

    SBC: INVERSEON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 5% of Americans have asthma, an inflammatory airway disease whose hallmark is airway hyper-reactivity (AHR). During AHR, bronchial smooth muscles rapidly constrict resulting in airway obstruction. Most patients self-administer inhaled beta2-adrenoceptor (beta2AR) agonists such as salmeterol for relief of this life-threatening event. Unfortunately, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Preclinical development of the tsetse thrombin inhibitor

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Thromboembolic disease is a major cause of morbidity and mortality in the developed world. Despite the need for effective therapies for treating and preventing pathologic activation of thrombosis, there are relatively few currently available alternatives to intravenous heparin. The total commercial market for antithrombotic agents has been estimated at 2 billio ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. HIGH THROUGHPUT GENOTYPING TECHNOLOGY

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a need for inexpensive high throughput platforms for analyzing large number of single nucleotide polymorphisms. In this proposal, we describe the development of a technique, which will enable more than 10,000 SNPs to be analyzed in a single tube and its transfer to a commercial entity (ParAllele Genomcis Inc.). T ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Multi-sample Solids NMR Probe

    SBC: REVOLUTION NMR LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this application is to enable more efficient and cost-effective utilization of solid state NMR systems for health care research. Solid-state NMR spectroscopy is an important tool for the analysis of Pharmaceuticals and biological compounds such as proteins, but is often not used due to the length of time required to collect data. The specific a ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. FLUOROPHORE GLYCOSYLATION PROFILES--PROSTATE CANCER TEST

    SBC: Glyko, Inc.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  6. Modification of Intervertebral Disk Fatigue Resistance

    SBC: Ampac Biotechnology, Inc.            Topic: N/A

    DESCRIPTION (Provided by Applicant): An investigation is proposed exploring the use of biochemical reagents to improve fatigue resistance of intervertebral disc tissue. While not well quantified, the capacity of spinal tissue to withstand repetitive loading is a critically important factor in the progression of spinal osteoarthritis. Current treatments for ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. Use of Self-Assembled Crystals in Cyanide Detection

    SBC: CHEMMOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): ChemMotif, Inc. is developing a range of sophisticated test strips that are reliable and sufficiently sensitive to be useful in public health, environmental, and homeland security applications. The objective of this proposal is the development of an improved analytical test strip for the determination of cyanide in water at or below EPA actionable levels (0. ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. EARLY BIOMARKER CHANGES IN DIABETIC NEPHROPATHY

    SBC: Biomedical Research Models, Inc.            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
  9. Image-Guided Minimally Invasive Robotic Surgery

    SBC: INTUITIVE SURGICAL            Topic: N/A

    DESCRIPTION (provided by applicant): Image-guided surgery allows surgeons to specifically target diseased tissue while sparing healthy tissue, reducing morbidity and improving patient outcomes. Minimally invasive surgical techniques deliver specific intervention without the morbidity associated with large open incisions. Image-guidance technology has the potential to provide significant benefit ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. TARGETED CPG OF CCR5 GENE--NOVEL HIV THERAPY

    SBC: SANGAMO BIOSCIENCES, INC.            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
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