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SBC: TOYON RESEARCH CORPORATION Topic: NGA181004
Toyon Research Corp. proposes development of a system that automates disaster assessment based on fusion of overhead and ground-basedimages, video, and other data. In Phase I, we will investigate various possible data sources and the benefits of fusing the data in automatedanalysis. We will select and curate data for processing in a Phase I feasibility study. Damage assessment will be performed in ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: TOYON RESEARCH CORPORATION Topic: NGA181006
Toyon Research Corporation proposes to research and develop algorithms for generalized change detection, by leveraging and exploringexisting and proven effective traditional and deep learning methods, with a unique 3D reconstruction component. The vast majority of themassive amounts of imagery data will have small pixel level differences due to a multitude of unimportant changes: minor misregistra ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: REAL-TIME ANALYZERS INC Topic: CBD181006
While this solicitation describes the need for better sampling methods and more rugged mass spectrometers to meet this DoD requirement, the topic author agreed to consider our alternative approach, which employs existing DoD Raman spectrometers. The goal of this proposed project (through Phase III) is to develop a Field-Usable Designer Drug Analyzer capable of identifying and quantifying drugs in ...SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
SBC: INNOSENSE CORPORATION Topic: CBD181004
Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
Sequential Phase II Proposal for Smartphone Application for Mask Sizing and Projecting Quantitative FitSBC: Physical Optics Corporation Topic: CBD181006
To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
SBC: CFD RESEARCH CORPORATION Topic: CBD18A001
In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: MAPP BIOPHARMACEUTICAL, INC. Topic: CBD18A002
There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Flow Pharma, Inc. Topic: CBD18A002
Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: OPTO-KNOWLEDGE SYSTEMS INC Topic: SOCOM182001
OKSI will demonstrate autonomous operations concepts for self-guided munition with Fire-Before-Lock-On-Target capabilities and with obstacle avoidance and anti-defilade targets.We will assess the feasibility of implementing the technology in medium caliber munitions.SBIR Phase I 2018 Department of DefenseSpecial Operations Command
SBC: Tanner Research, Inc. Topic: SOCOM182003
Tanner proposes to develop a dynamic heat pump system with self-contained, rechargeable battery and driving circuit that operates as a Combination Thermal Recycler (CTR). By utilizing thermal reservoirs coupled with the rebreather mask, heat can be efficiently recycled in proportion to the temperature difference between the exhaled air stream and a target inhaled air temperature. No power would be ...SBIR Phase I 2018 Department of DefenseSpecial Operations Command