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SBC: Arete Associates Topic: NGA181008
We propose to build ARGON, the ARet Ground-to-Overhead Network. The network will ingest analyst-supplied ground-level imagery ofobjects and retrieve instances of those objects in overhead collections, providing tips back to the analysts. A proprietary method of trainingthe network, leveraging in-house capabilities, data sources, and tools, will be critical to its success. During Phase I, we will p ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: MAYACHITRA, INC. Topic: NGA181005
Building interpretable, composable autonomous systems requires consideration of uncertainties in the decisions and detections theygenerate. Human analysts need accurate absolute measures of probability to determine how to interpret and use the sometimes noisy resultsof machine learning systems; and composable autonomous systems need to be able to propagate uncertainties so that later reasoningsyst ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: TOYON RESEARCH CORPORATION Topic: NGA181010
The National Geospatial-Intelligence Agency (NGA) ingests and analyzes raw imagery from multiple sources to form actionable intelligenceproducts that can be disseminated across the intelligence community (IC). To effectively meet these demands NGA must continue to improveits automated and semi-automated methods for target detection and classification. Of particular concern is furthering NGA's abil ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: TOYON RESEARCH CORPORATION Topic: NGA181006
Toyon Research Corporation proposes to research and develop algorithms for generalized change detection, by leveraging and exploringexisting and proven effective traditional and deep learning methods, with a unique 3D reconstruction component. The vast majority of themassive amounts of imagery data will have small pixel level differences due to a multitude of unimportant changes: minor misregistra ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: CFD RESEARCH CORPORATION Topic: CBD18A001
In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: MAPP BIOPHARMACEUTICAL, INC. Topic: CBD18A002
There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Flow Pharma, Inc. Topic: CBD18A002
Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: INTELLISENSE SYSTEMS INC Topic: NGA181004
To address the NGA need for algorithms that fuse observables from over-flight operations and from ground sources to automatically estimatethe degradation of urban environments due to battle damage or natural disasters, Intellisense Systems, Inc. (ISS) proposes to develop a newBayesian Urban Degradation Assessment (BUDA) software system. It is based on the integration of multiple damage assessment ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: TOYON RESEARCH CORPORATION Topic: NGA181004
Toyon Research Corp. proposes development of a system that automates disaster assessment based on fusion of overhead and ground-basedimages, video, and other data. In Phase I, we will investigate various possible data sources and the benefits of fusing the data in automatedanalysis. We will select and curate data for processing in a Phase I feasibility study. Damage assessment will be performed in ...SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: INNOSENSE CORPORATION Topic: CBD181004
Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense