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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. The ASI--A Multimedia Interactive Version

    SBC: Inflexxion, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  2. Quantitative Tagged Antigen Magnetic Deposition

    SBC: Institute Guilfoyle            Topic: N/A

    This project is a feasibility study to demonstrate that Tagged Antigen Magnetic Deposition (TAMD) csuccessfully select and deposit tagged human lymphocytes on a microscope slide for analysis, countinstorage. Selective tagging and magnetic deposition of subpopulations of morphologically intact lymphinnovative and inexpensive technology suitable for wide distribution to clinical laboratories. Indivd ...

    SBIR Phase I 1995 Department of Health and Human Services
  3. Anti-inflammatory Drug Discovery Using DictyoSuitelium

    SBC: Leukosite, Inc.            Topic: N/A

    As critical components of cell-mediated immunity, chemokine and chemokine receptors play pivotal roleukocyte migration and cell adhesion. A long term objective is to discover and develop small molecucan block the binding of chemokine to its receptor or the downstream signaling pathways, and therebyan essential step in the inflammation process. DictyoSuitelium is a simple eukaryote that exhibits wr ...

    SBIR Phase I 1995 Department of Health and Human Services
  4. Drug Design for Treatment of Inflammatory Bowel Disease

    SBC: Leukosite, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  5. Multimedia Software Re--HIV/AIDS, Accessible to The Deaf

    SBC: Litterst And Associates            Topic: N/A

    Multimedia technology offers users the opportunity to make connections between diverse forms of inf(text, pictures, animation, digital video, and sound), to navigate through information in a non-linemanner, as well as to learn by directly interacting with the software. Traditional multimedia softwaextensive use of sound effects, spoken English, and music as well as written text and is thus inacceT ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. Aid for Implicit Learning of Food Groups Among Seniors

    SBC: Massachusetts Institute            Topic: N/A

    We will develop and pilot test an innovative approach to enhancing the dietary knowledge of peopleparticularly those who either have or are at risk for Type II diabetes, the type which affects peoploverweight and accounts for 90% of the 14,000,000 Americans who have diabetes. This project will deveducational tool, based on cognitive and neuropsychological research on memory: a deck of playing cato ...

    SBIR Phase I 1995 Department of Health and Human Services
  7. High Specificity Therapeutic Agent for Prostate Cancer

    SBC: MATRITECH, INC.            Topic: N/A

    A prostate cancer specific nuclear matrix protein (NMP). PC-1. has been identified (1). Matritech sproduced a number of monoclonal antibodies to PC-1 and have characterized the antibodies by immunoflstaining of human adenocarcinoma cells showing nuclear localization with a punctuate staining patteralso been shown to react with PC-1 by two dimensional western immunoblot analysis. Our goal is to cht ...

    SBIR Phase I 1995 Department of Health and Human Services
  8. Drug Screening Assay for Novel Chemotherapeutic Agents

    SBC: MATRITECH, INC.            Topic: N/A

    The nuclear matrix protein NuMA ( Nuclear Mitotic Apparatus) is present at greater than tenfold higmalignant tissues relative to normal tissues. Scientists at Matritech have shown that interference wantisense oligonucleotide technology dramatically slows the growth of cancer cells both in soft agarWe believe that the combination of its overexpression in cancerous tissue and its essential role form ...

    SBIR Phase I 1995 Department of Health and Human Services
  9. Nuclear Matrix Proteins Cc-4/Cc-5--Colon Cancer Markers

    SBC: MATRITECH, INC.            Topic: N/A

    Two putative colon cancer markers, CC-4 and CC-5, have been identified in colon cancers but not norMatritech scientists. MAbs specific for these proteins have been selected by immunofluorescent nucleon the CC- 4/CC-5-positive tumor cell line DLD and immunoblots against DLD-extracted nuclear matrixFollowing further characterization of CC-4-- and CC- 5-specific antibodies by two- dimensional immunma ...

    SBIR Phase I 1995 Department of Health and Human Services
  10. Cloning of Heparinases from Flavobacterium Heparinum

    SBC: MATRIX ENGINEERING            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services

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