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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. FERRITE PARTICLES AS NMR IMAGING CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    AS PART OF A COLLABORATIVE EFFORT WITH THE DEPARTMENT OF RADIOLOGY AT THE MASSACHUSETTS GENERAL HOSPITAL, ADVANCED MAGNETICS INTENDS TO ASSESS THE POTENTIAL OF LIVER-TARGETED,FERRITE-BASED CONTRAST AGENTS TO ENHANCE THE POTENTIAL OF MAGNETIC RESONANCE (MR) IMAGING FOR DETECTION OF LIVER METASTASES USING A RAT TUMOR MODEL. ALTHOUGH MOST STUDIES WITH MR CONTRAST AGENTS HAVE INVOLVED ONLY IONS OR ION ...

    SBIR Phase II 1988 Department of Health and Human Services
  2. HEPATOCYTE DIRECTED MAGNETIC RESONANCE CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  3. PORTABLE OXYGEN-ENRICHER FOR INHALATION THERAPY

    SBC: A/g Technology Corp.            Topic: N/A

    HOME CARE INHALATION THERAPY REQUIRES A READY SUPPLY OF OXYGEN FOR PATIENT COMFORT. UNFORTUNATELY, AVAILABLE TECHNIQUES FOR SUPPLYING OXYGEN ALL SUFFER FROM MAJOR DRAW- BACKS. THE MOST NOTABLE COMMON PROBLEM IS EXCESSIVE WEIGHT WHICH LIMITS PATIENT MOBILITY BOTH INSIDE AND OUTSIDE THE HOME. THE OBJECTIVE OF THIS RESEARCH IS TO DEMONSTRATE THE FEASIBILITY OF DEVELOPING A TRULY PORTABLE HOME CARE UN ...

    SBIR Phase II 1988 Department of Health and Human Services
  4. UTILIZATION OF 180-DEGREE PULSES IN HIGH-SPEED MRI

    SBC: Advanced Nmr Systems, Inc            Topic: N/A

    THIS RESEARCH WILL CONTRIBUTE TO THE DEVELOPMENT OF A WHOLE-BODY MAGNETIC RESONANCE IMAGING (MRI) SYSTEM CAPABLE OF ACQUIRING COMPLETE TOMOGRAPHIC PROTON IMAGES IN ABOUT 50 MILLISECONDS. IN PARTICULAR, THE POTENTIAL UTILIZATION OF 180-DEGREE RADIOFREQUENCY PULSES IS ADDRESSED AS A MEANS OF ELIMINATING ARTIFACTS THAT ARISE AS A RESULT OF MAGNETIC FIELD STRENGTHS MANDATED BY SIGNAL-TO-NOISE RATIO AN ...

    SBIR Phase II 1988 Department of Health and Human Services
  5. IMPROVED RFLP ANALYSIS FOR GENETIC LINKAGE MAPPING

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    ONE OF THE MOST ACTIVE AND CHALLENGING FIELDS IN MOLECULAR BIOLOGY TODAY IS THE GENETIC STUDY OF EUKARYOTIC SYSTEMS. ONE RAPIDLY GROWING AREA IN THIS FIELD IS THE STUDY OF RESTRICTION FRAGMENT LENGTH POLYMORPHISMS (RFLPS). THIS PROCEDURE USES RADIOLABELED HYBRIDIZATION TECHNIQUES AND AUTORADIOGRAPHY TO CONSTRUCT A HUMAN GENETIC LINKAGE MAP BY IDENTIFYING GENETIC MARKERS ALONG THE GENOME. THE PARTI ...

    SBIR Phase I 1988 Department of Health and Human Services
  6. INTRAOPERATIVE, REGIONAL MYOCARDIAL BLOOD FLOW MONITOR

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    CORONARY ARTERY BYPASS IS ONE OF THE MOST WIDELY PRACTICED PROCEDURES FOR THE TREATMENT OF PATIENTS WITH CORONARY ATHEROSCLEROSIS, YET A SIMPLE AND RAPID METHOD FOR ASSESSINGTHE EFFECTIVENESS OF THE PROCEDURE WHILE IT IS BEING PERFORMED IS NOT CURRENTLY AVAILABLE. IT WOULD BE EXTREMELYUSEFUL IF A DIRECT MEASUREMENT OF REGIONAL MYOCARDIAL BLOOD FLOW (RMBF) COULD BE MADE PRIOR TO THE CLOSING OF THE ...

    SBIR Phase II 1988 Department of Health and Human Services
  7. REAL TIME IMAGING SYSTEM FOR SCREENING DNA LIBRARIES

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  8. RENAL BLOOD FLOW MONITOR FOR ICU PATIENTS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  9. ATTENUATION OF THE NYCBH VACCINE STRAIN OF VACCINIA

    SBC: APPLIED BIOTECH CONCEPTS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  10. COMMUNICATION TRAINING FOR SCHIZOPHRENICS VIA VIDEODISC

    SBC: ASIP, INC.            Topic: N/A

    THE SPECIFIC AIM OF THIS PHASE 1 SBIR PROPOSAL IS TO DEVELOPA CORE LIBRARY OF VIDEODISCS WHICH CAN BE USED TO TRAIN ADULT SCHIZOPHRENICS AND THEIR FAMILIES IN COMMUNICATION SKILLS. DURING PHASE 1, THE LIBRARY WILL BE CONSTRUCTED, SOFTWARE WILL BE WRITTEN, AND A SINGLE-CASE EXPERIMENTAL DESIGN WILL BE USED TO EVALUATE THE EFFECTS OF THIS TECHNOLOGY WITH 3 ADULT SCHIZOPHRENICS. THIS TECHNOLOGY WILL, ...

    SBIR Phase I 1988 Department of Health and Human Services

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