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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. CERAMIC MATERIALS FOR IMPROVED CONTACT LENSES

    SBC: Merix Corp            Topic: N/A

    IN THIS PROGRAM, THIN SHEETS OF OPTICALLY CLEAR, CERAMIC MATERIALS WILL BE PRODUCED AND FABRICATED INTO LENSES FOR EVALUATION AS CONTACT LENS MATERIALS. THE MATERIALS WILL PERMIT HIGH OXYGEN FLUX TO AND FROM THE CORNEA, PREVENTING ATOXIA AND SHOULD HAVE HIGH WETTABILITY. THEY WILL ALSO BE STRONG, HARD AND RESISTANT TO HARD LENS CLEANING SOLUTIONS. INITIAL EVALUATION WILL INCLUDE OPTICAL PROPERTIES ...

    SBIR Phase I 1988 Department of Health and Human Services
  2. IMPROVED BILE ACID ADSORBENTS

    SBC: Merix Corp            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  3. RAPID AND AUTOMATED IN VITRO TEST SYSTEM FOR SCREENING ANTICANCER AGENTS

    SBC: Microdrop/intellimetrics            Topic: N/A

    WE PROPOSE RESEARCH AND DEVELOPMENT DIRECTED TOWARDS AN IMPROVED AND MOSTLY AUTOMATED IN VITRO MAMMALIAN LONG TERM SURVIVAL ASSAY (CLONOGENICITY) TO BE USED FOR SCREENING ANTICANCER DRUGS. THE METHODS UNDERLYING THIS APPROACH ALLOW RAPID MEASUREMENTS ON LARGE NUMBERS OF CELLS AND COLONIES WHICH CAN BE MOSTLY AUTOMATED, AND WHICH CAN BE USED UNDER A WIDE VARIETY OF CELL CULTURE AND CYTOTOXICITY ASS ...

    SBIR Phase I 1988 Department of Health and Human Services
  4. KINEMATIC ANALYSIS OF PEDIATRIC MOVEMENT DISORDERS

    SBC: Moco, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS RESEARCH IS TO INVESTIGATE WHETHER KINEMATIC PROFILES OF LIMB TRAJECTORIES CAN BE USED TO DISTINGUISH NORMAL FROM ABNORMAL MOVEMENT IN INFANTS AND YOUNG CHILDREN. FIRST, THE DEVELOPMENT OF UPPER EXTREMITY MOTOR CONTROL WILL BE INVESTIGATED BY USING KINEMATIC PROFILES TO STUDY VISUALLY-GUIDED REACHING TO A TOY TARGET. SECOND, KINEMATIC ANALYSIS OF LIMB TRAJECTORIES WILL BE COM ...

    SBIR Phase I 1988 Department of Health and Human Services
  5. MULTICHANNEL MICROELECTRODES FOR NEURAL RECORDING

    SBC: Network Instruments            Topic: N/A

    A MULTICHANNEL MICROELECTRODE THAT CAN MONITOR POTENTIALS FROM MANY NEARBY NEURONS SIMULTANEOUSLY WILL BE HIGHLY BENEFICIAL TO RESEARCHERS IN NEUROSCIENCE. SUCH A TOOL WILLALLOW HIGHLY RFFICIENT DATA COLLECTION AND THE STUDY OF NEURAL GROUP INTERACTIONS DURING ANIMAL BEHAVIOR. THE AIM OF THE PROPOSED RESEARCH IS TO DESIGN, DEVELOP AND EVALUATE A MULTICHANNEL MICROELECTRODE SYSTEM FOR MASS PRODUCTI ...

    SBIR Phase I 1988 Department of Health and Human Services
  6. MULTICHANNEL MICROELECTRODES FOR NEUROCHEMICAL SENSING MULTICHANNEL MICROELECTRODES FOR NEUROCHEMICAL SENSING

    SBC: Network Instruments            Topic: N/A

    A MULTICHANNEL MICROELECTRODE THAT MONITORS NEUROCHEMICAL CONCENTRATIONS FROM MANY NEARBY BRAIN SITES SIMULTANEOUSLY WILL BE HIGHLY BENEFICIAL TO BRAIN RESEARCHERS. SUCH A TOOLWILL ALLOW SCIENTISTS BOTH TO COLLECT DATA MORE EFFICIENTLY AND TO STUDY THE DYNAMICS OF NEUROCHEMICAL GRADIENTS DURING ANIMAL BEHAVIOR WITHIN ANY BRAIN STRUCTURE. THE AIM OF THE PROPOSED RESEARCH IS TO DESIGN, DEVELOP AND E ...

    SBIR Phase I 1988 Department of Health and Human Services
  7. AN EPIDEMIOLOGIC TOOL TO DETECT ANGINA PECTORIS IN BLACKS

    SBC: New England Research Institutes, Inc.            Topic: N/A

    ANGINA PECTORIS IS OFTEN CONSIDERED A MANIFESTATION OF CORONARY ARTERY ATHEROSCLEROSIS THAT IS ASSOCIATED WITH AN INCREASED MORTALITY RISK. OVERALL, CORONARY HEART DISEASE IS THE LEADING CAUSE OF MORBIDITY AND MORTALITY IN U.S. BLACKS. IN AN ATTEMPT TO STANDARDIZE THE DIAGNOSIS OF ANGINA PECTORIS IN EPIDEMIOLOGIC STUDIES, ROSE DEVELOPED A QUESTIONNAIRE FOR CARDIOVASCULAR FIELD SURVEYS WHICH HAS PR ...

    SBIR Phase I 1988 Department of Health and Human Services
  8. A TELEPHONE-LINKED COMPUTER SYSTEM FOR ELDER CARE

    SBC: New England Research Institutes, Inc.            Topic: N/A

    THE TELEPHONE-LINKED COMPUTER (TLC) SYSTEM HAS BEEN DEVELOPED AND TESTED TO CONVERSE AUTOMATICALLY BY TELEPHONE,USING COMPUTER-GENERATED SPEECH, WITH INDIVIDUALS IN ORDER TO MONITOR THEIR HEALTH STATUS, REPORT THE FINDINGS TO THEIRPROVIDERS OF CARE, AND GIVE THE PATIENTS INFORMATION AND FEEDBACK THAT REINFORCE DESIRABLE SELF-CARE ACTIVITIES. THELONG-TERM OBJECTIVE OF THE PROPOSED PROJECT IS TO DEV ...

    SBIR Phase I 1988 Department of Health and Human Services
  9. OF CELLS SYNCHROTRON X-RAY FLUORESCENCE MICRO-TOMOGRAPHY OF CELLS

    SBC: Radiation Science, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO DEVELOP A RESEARCH RESOURCE FOR STUDYING THE ROLE OF TRACE ELEMENTS IN CELLULARPROCESSES BY LOCALIZING THE ELEMENTS WITHIN THE ORGANELLES OF THE CELL USING MICRON SCALE COMPUTED TOMOGRAPHY (CT) OF SYNCHROTRON INDUCED FLUORESCENT X-RAYS. BECAUSE FLUORESCENCE CT NEEDS ONLY MINIMALLY PREPARED, THICK SAMPLES, THE PROBABILITY OF CONTAMINATION SHOULD BE MUCH LOWER THA ...

    SBIR Phase I 1988 Department of Health and Human Services
  10. HIGH AFFINITY LIGANDS FOR THE COCAINE RECEPTOR

    SBC: Research Biochemicals,            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services

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