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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. MRI Virtual Pathology of the Prostate: Multi-center multi-vendor application and validation

    SBC: QMIS            Topic: 102

    PROJECT SUMMARY The U.S. Preventative Task Force found current ultrasound-based screening methods unreliable, causing unnecessary biopsies and failing to detect clinically significant Prostate Cancer (PCa) in patients with an elevated prostate-specific antigen (PSA). Millions of men in the U.S. alone are currently at elevated risk for PCa, but there are no effective alternatives for screening. Alt ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Peptide Therapy for Corneal Wound Healing

    SBC: VISO Therapeutics Inc.            Topic: NEI

    PROJECT SUMMARY/ABSTRACT Acute corneal epithelial injuries (corneal abrasions, foreign bodies, contact lens related injuries) are extremely common (more than 1 million per year). Injuries like corneal abrasions may lead to downstream consequences like corneal infections and inflammation, vision loss, and chronic wounds. Very limited interventions are currently available for these wounds. The stand ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Development of the UValidate platform for the profiling of topically applied chemical agents.

    SBC: AMELIA TECHNOLOGIES LLC            Topic: R

    Project Summary Skin is the first line of defense against the outside environment. When the skin barrier is breached by UV irradiation (UVR) or toxic chemicals, living cell layers including epidermal keratinocytes, melanocytes and dermal fibroblasts are subjected to DNA damage. If unrepaired, this damage can lead to photoaging and cutaneous carcinogenesis. In fact, skin cancer is by far the most c ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Development of (R,S')-MNF as a dual-targeted therapy for pancreatic cancer

    SBC: PAZ PHARMACEUTICALS LLC            Topic: NCI

    Summary Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the U.S. with a 5-year survival rate of andlt;9%. The poor prognosis is partially due to resistance to standard of care treatments including gemcitabine (Gem) and Gem+nab-paclitaxel (n-PTX). The transcription factors HIF-1α and c-MYC are at the center of the mechanisms producing Gem and n-PTX resistance ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Developing an app-based behavioral intervention to help depressed individuals return to work

    SBC: INSPIRATION AT WORK INC            Topic: 104

    PROJECT SUMMARY Significance: The overarching goal of this proposal is to develop an intervention to help unemployed individuals with major depressive disorder (MDD) return to work. Individuals who lose their jobs are at risk for MDD and other psychiatric disorders. Because a core feature of MDD is decreased motivation, unemployed individuals with MDD can enter a `vicious cycle' where their depres ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Evaluation of a beta cell replacement therapy combined product that avoids the need for immunosuppression via localized induction of immune tolerance

    SBC: Regenerative Medical Solutions Inc            Topic: 200

    Project Summary/Abstract Diabetes is an increasingly important health problem worldwide. Despite recent advances in diabetes care, including long-acting insulin formulations, insulin pumps, and continuous glucose monitors, a majority of diabetic patients cannot achieve currently recommended targets for blood glucose control. Although transplantation of diabetic patients with donor-derived pancreat ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Development and Evaluation of Rosette Array Technology for HumanNeurodevelopmental Toxicity Screening

    SBC: Neurosetta LLC            Topic: R

    Project Summary Pre-clinical and pre-field toxicology testing of new drugs and chemicals does not routinely include direct assessment of human developmental neurotoxicity (DNT). Current standards for DNT testing require use of animal models with limited throughput and significant differences from human central nervous system (CNS) development. As such, many chemical products have required post-app ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Adjustable prosthetic sockets for children and adolescents with lower limb loss to accommodate growth

    SBC: IFIT PROSTHETICS, LLC            Topic: NICHD

    Pediatric limb loss, although relatively infrequent compared to adults, results in substantial hardship for children and their families. The principal business interest? iFIT Prosthetics, LLC®? successfully developed and manufactured innovative, fully adjustable, transtibial and transfemoral prosthetic devices, and demonstrated their safety, comfort, and functionality in adults. Made of injection ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Development of 4-(aroylamino)piperidine-based entry inhibitors as anti-influenza therapeutics

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the orthomyxoviridae family, and have a negative-sense, segmented RNA genome, which can cause seasonal or pandemic flu with high morbidity and significant mortality. Vaccination is the most prevalent prophylactic means for controlling influenza infections. However, an effective vaccine usually takes at least six months to develop. Furthermore, vaccination has limited ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. PROJECT TITLE: COLLABORATE IN THE CLOUD TO ENABLE PRECISION ONCOLOGY

    SBC: NAVIPOINT GENOMICS LLC            Topic: 407

    Precision oncology offers great potential in improving cancer-related diagnosis and treatment. The Navipoint Platform provides state of the art tools, pipelines, and cloud-based resources, which will be extended and integrated with CRDC data and resources in order to enable “Collaborate in the Cloud” capabilities to help realize this promise. The product of this SBIR will be a production-grade ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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