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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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High throughput antibiotic discovery from the uncultivated microbial majority.
SBC: NOVOBIOTIC PHARMACEUTICALS, LLC Topic: NIAIDDESCRIPTION (provided by applicant): The long-term goal of this project is to develop novel, broad-spectrum antibiotics against both biowarfare agents and common drug resistant pathogens. The potential use of engineered, multi-drug-resistant strains as agents of bioterrorism, and the current spread of conventional drug resistant pathogens necessitate the development of novel antibiotics. Most anti ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Sparker Array for Improved Electro-Hydraulic Lithotripsy (EHL)
SBC: Phoenix Science & Technology Topic: NIDDKDESCRIPTION (provided by applicant): Shock wave lithotripsy (SWL) is the first line treatment for the majority of patients with kidney stones. The gold standard in SWL is still considered to be the Dornier HM3, which was the first lithotripter introduced into the US. The HM3 is an electrohydraulic lithotripter (EHL) that uses a single underwater sparker as a shock wave source. The HM3 has the dr ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Device for Automating Zebrafish Processing
SBC: PHYLONIX PHARMACEUTICALS, INC. Topic: NIGMSDESCRIPTION (provided by applicant): Although conventional sample handling can be adapted for use with processing zebrafish, development of appropriate analytical tools has not kept pace with the increasing use of this animal model for compound screening. In this research, we propose to develop a device to automate zebrafish processing. Zebrafish embryos, which are permeable to small molecules, pr ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Brain Cancer Xenotransplant Model for Drug Screening
SBC: PHYLONIX PHARMACEUTICALS, INC. Topic: NCIDESCRIPTION (provided by applicant): In this research, we will develop zebrafish as a new xenotransplant animal model to assess brain cancer progression and identify potential drug candidates. Brain cancer accounts for approximately 10 - 30% of adult cancers and many forms of cancer can metastasize to the brain. Although immunodeficient mice and rats have played an important role as hosts for bra ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Product Development and Demonstration of Automated Mandibular Distractor
SBC: PHYSICAL SCIENCES INC. Topic: NIDCRDESCRIPTION (provided by applicant): Distraction Osteogenesis is becoming the preferred method to obtain the skeletal expansion necessary to correct congenital and acquired craniomaxillofacial deformities. The procedure consists of an osteotomy at the expansion site and a mechanical device to separate the resulting segments at 1mm/day. Natural osteogenic processes produce new bone to fill the exp ...
SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health -
OsteoMark- A Navigation Aid for Orthognathic Surgical Procedures
SBC: PHYSICAL SCIENCES INC. Topic: NIDCRDESCRIPTION (provided by applicant): Having successfully completed a Phase I program, we propose to continue the development and demonstration of OsteoMark, a tool for implementing computer-based plans for orthognathic surgery. Physical Sciences Inc., is leading the development of the product with support from our clinical partners in the Dept of Oral and Maxillofacial Surgery at the Massachusetts ...
SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health -
High Performance Multimodal Adaptive Optics Retinal Imaging
SBC: PHYSICAL SCIENCES INC. Topic: NEIDESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) has successfully completed a Phase I program to develop a multimodal adaptive optics (AO) retinal imager for diagnosis of retinal diseases, including glaucoma, diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinitis pigmentosa (RP). The development represents the first ever high performance AO system constru ...
SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health -
Optical Coherence Tomography Based Freeze Drying Microscopy
SBC: PHYSICAL SCIENCES INC. Topic: NIBIBDESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) in collaboration with the University of Connecticut, School of Pharmacy (UConn), proposes to develop an advanced freeze-drying microscopy (FDM) system for determining drug formulation collapse temperature. During the Phase I program PSI will demonstrate the application of Optical Coherence Tomography (OCT) for imaging the 3D structu ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Process Analytic Technologies (PAT) for Biologics
SBC: PHYSICAL SCIENCES INC. Topic: NCIThe development of biologic drugs for cancer treatment often requires formulations that must be lyophilized to produce stable drug products. The process of developing a drug formulation and freeze-drying process begins with laboratory experiments followed by scaled-up to pilot and production scale lyophilizers. A major challenge during early formulation and lyophilization process development is th ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Compact Line Scanning Adaptive Optics Retinal Imager
SBC: PHYSICAL SCIENCES INC. Topic: NEIDESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) has successfully completed a Phase I program demonstrating the feasibility of integrating adaptive optics (AO) into a line scanning laser ophthalmoscope (LSLO). The bench-top AO-LSLO instrument significantly reduces the size, complexity, and cost of research AOSLOs, for the purpose of moving adaptive optics imaging more quickly into ...
SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health