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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain Injury
SBC: Mitovation, Inc. Topic: 101Neonatal hypoxia ischemia is a known cause of cerebral damage resulting from inadequate blood flow and or oxygen delivery to the infant brain beforeduringor after birthThe occurrence among hospital deliveries isperfull term births with a drastic increase among premature newbornsThe deficit in oxygen delivery to the brain results in extensive damage and severe disabilitiesRestoration of blood flow ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Innovative Nose-to-Brain Anticancer Drug Transport Facilitated by NEO100
SBC: NEONC TECHNOLOGIES INC Topic: 102Project Summary Abstract Many pharmaceutical agents are highly potentbut are unable to exert substantial therapeutic activity against disorders of the brainbecause the blood brain barrierBBBeffectively prevents their access to the site of intracerebral diseaseFor examplethe majority of glioblastoma patientsdespite the best efforts of current medical caredie within two years after diagnosisHencethe ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Inter-examiner Agreement of a Novel Device for the Measurement of Cervical Dilation in Labor: A Randomized Controlled Trial
SBC: Elm Tree Medical Inc. Topic: NICHDMeasurement of cervical dilation during late pregnancy and labor informs decisions in the management of labor and deliveryPrior published research suggests that practitioners are onlytoaccurate when judging cervical simulatorsWhen measuring laboring womentwo practitionersandaposmeasurements agree onlyof the timeDrEva Martin of Elm Tree Medical Incdeveloped a novel deviceDilaCheckto enable practiti ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Interventions to Improve Reproductive Health among Adolescents
SBC: DFUSION INC. Topic: NICHDAlthoughyear olds are onlyof the U Ssexually active populationthey account for nearlyof themillion new cases of sexually transmitted infectionsSTIeach yearAlthough historically lowthe U Steen pregnancy rate continues to be one of the highest in the developed worldEvidence based prevention efforts can help avoid the costs and health consequences associated with STIs and unwanted teen pregnancy amon ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
In Vivo Assessment of Embryonic Stem Cell Teratoma Prevention
SBC: BIOINVISION INC Topic: NICHDDESCRIPTION (provided by applicant): The capacity to evaluate the teratoma forming potential of differentiated embryonic stem cell populations represents an urgent need before widespread therapeutic application of these cells is possible. Researchers at Case Western Reserve University and BioInVision, Inc. will join together to create platform technologies for validating existing embryonic stem ce ...
STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
In vivo expansion of human hepatocytes in Fah-/-Rag-/-Il2rg-/- mice
SBC: Yecuris Corporation Topic: NCRRDESCRIPTION (provided by applicant): The liver is the site of many metabolic processes, including metabolism of xenobiotics such as pharmaceutical compounds. Drug metabolism is highly species specific and can vary significantly between individuals of the same species. To date no reliable experimental system capable of predicting the human-specific metabolic conversion of candidate small molecules ...
STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Kinetic image cytometry assays for neuronal activity/toxicity
SBC: VALA SCIENCES, INC. Topic: NCIDESCRIPTION (provided by applicant): The proposed project is a Phase I STTR collaboration between Vala Sciences Inc, a small business that specializes in the development of cell-based high content/high throughput assays, and the Sanford Burnham Medical Research Institute, a worldwide leader in biomedical research. The project will develop an assay (Kinetic Image Cytometer-Neuron, or KIC-Neuron) to ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health -
Lighting System for Premature Infant Incubators
SBC: WHITE BRIAR CORPORATION Topic: NICHDProject Summary Incubators have been in use since the 19th century and have significantly improved survival for premature infants. However, incubator lighting systems still can still be improved. Proposed is a project to develop and test the feasibility and acceptability of a solid state lighting (SSL) system for use with neonatal intensive care unit (NICU) incubators. The system would 1) promote ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health -
Live-Cell Fluorescence Lifetime FRET Assays for HTS
SBC: Fluorescence Innovations, Inc. Topic: NIDADESCRIPTION (provided by applicant): This project will establish proof-of-concept for a powerful and versatile implementation of live-cell assays in a true high-throughput screening (HTS) format for small-molecule drug discovery. The technological basis isfluorescence lifetime (FLT) readout of FRET between fluorescent fusion proteins. Lifetime measurement is needed in HTS to overcome the low preci ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health -
Long-term Sensing in the Brain Using Sub-cellular Edge Electrode Arrays
SBC: Neuronexus Technologies, Inc. Topic: NINDSDESCRIPTION (provided by applicant): Next generation neural probe technology must enable neuroscientists to bridge the gap between neurons and neuronal pools to fully understand the orchestrated 'temporal dynamics' of the brain. This will require high-density, stable recordings in longitudinal experiments. Similarly, next generation brain machine interfaces (BMI) must improve longevity and reliabi ...
STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health