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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Targeting bacteria, the innate response of the middle ear to infection, and host-pathogen interactions, using topical and transtympanic applications for the treatment of otitis media.

    SBC: EARNANO LLC            Topic: NICHD

    Otitis media is a world wide disease primarily affecting the pediatric population under the age ofyearsIt is the most common reason for pediatric care visits and antibiotic therapyOver prescription and poorcompliance have led to a reduced susceptibility of bacteria to antibiotics andconsequentiallyto recurrent and chronic ear diseasesClearlythere is a compelling need to investigate alternative the ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. BEST-OUD: Behavioral Economic Screening Tool of Opioid Use Disorder for use in clinical practice

    SBC: BEAM Diagnostics, Inc.            Topic: 41

    PROJECT SUMMARY Fatal overdose from opioid misuse is one of the most pressing issues affecting the modern worldAs one of the nation s leading preventable causes of deatha critical line of defense against opioid use disorderOUDmust be standardized screening provided by the patient s primary care physicianpsychiatristand or counselorStandardized screening methods for opioidshoweverare simply inferio ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. An Engineered Nanoimmunotherapy for Melanoma

    SBC: IMMUNOBLUE, LLC            Topic: NCI

    PROJECT SUMMARY Melanoma is one of the most prevalent cancers and is estimated to account for overdeaths inin the United States aloneAlthough highly curable when detected earlytheyear survival rates decline precipitously for patients with regionaland metastaticmelanoma indicating a lack of efficacy of conventional therapiesand a strong need for novel therapies for this patient populationIn respons ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A 3D Printed Resorbable Antimicrobial Envelope to Prevent Infection of Implanted Cardiac Devices

    SBC: N8 MEDICAL INC            Topic: NHLBI

    ABSTRACT Infection is a serious and potentially fatal complication of surgery to deliver cardiovascular implantable electronic devicesCIEDsi epacemakers and implantable cardioverter defibrillatorsUntreated device related infection is associated with mortality rates as high asCurrentlyonly one antibiotic impregnated mesh has been FDA approved for placement in surgical incisions to reduce infections ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Coherence Gated Doppler for Dentistry

    SBC: CREATV MICROTECH INC            Topic: NIDCR

    AbstractIf there were a simple and accurate means totake the pulseof a toothi efunctionally similar to a pulse oximeter that could be clipped on a tooth rather than the tip of a fingerthe quality and cost of dental care would be significantly improvedThe ability to measure dental pulp blood flow provides the most direct means to determine the viability of a tooth and is a vital piece of informatio ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Noninvasive System for Detection of Sleep Apnea in Animals

    SBC: NEOGENE BIOSCIENCES, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The long term goal of this project is to develop and commercialize noninvasive equipment, called the sleep and respiratory track (SARTrak) system, for high throughput detection of sleep apnea in animals. The specific goal for the Phase I application is to design and evaluate a basic model of the SARTrak system with eight chambers (one chamber per animal), i.e. ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Novel LANCL2-based Anti-diabetic Compounds

    SBC: Biotherapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): About 28.3 million Americans have type II diabetes (T2D) and over 40.1% of middle-aged adults have prediabetes, a condition characterized by impaired glucose tolerance and insulin resistance. Current antidiabetic medications are effective in improving insulin sensitivity, but their chronic administration has significant side effects suc as cardiovascular compli ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Preparation and Characterization of 2nd Generation HIV-1 Maturation Inhibitor Dru

    SBC: DFH Pharma, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): Despite advances in the development of HIV drugs there remains a need for new therapies. Toxicities associated with long term use of many of the approved HIV drugs coupled with the development of resistance drives the need for new and novel antivirals. Maturation inhibitors (MIs) represent one such class of HIV therapies. HIV maturation inhibitors block virus r ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Survey and Test Platform for Use in Underserved Populations

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: NEI

    DESCRIPTION (provided by applicant): Advanced Medical Electronics Corp, in collaboration with the Johns Hopkins University School of Medicine, proposes to develop a hardware/software platform suitable for administering a variety of tests and survey instruments to underserved populations in settings that can range from living rooms to libraries, community centers to nursing homes, and from inner ci ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Position tracking and mobility assessment system for indoor monitoring of elders

    SBC: EMBEDRF LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The long term objective of this project is to enable elderly persons to independently live within their own homes later into their lives with the assurance that their safety and well-being can be remotely monitored by health care professionals. A critical component of remote health care monitoring is physically tracking the location of the patient within a livi ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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