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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
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SBC: GRIFFIN LABORATORIES, INC. Topic: NIDCD
DESCRIPTION (provided by applicant): The most common artificial voice source for post-laryngectomy speech rehabilitation is the hand-held buzzer or electrolarynx (EL). This device is relatively easy to use and enables most laryngectomees to verbally communicate, but with reduced intelligibility and markedly degraded naturalness. In addition, EL speech is often described as robotic and monotone, at ...STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: VISDEX CORP Topic: NEI
DESCRIPTION (provided by applicant): Since its introduction in the 1960's, fluorescein angiography (FA) has been the gold standard for retinal vascular diagnosis. However, FA is costly, invasive, and time-consuming, which limits its usefulness as a screening tool. As a potential non-invasive alternative to FA for diagnosing retinovascular disease, we have developed an imaging method called ph ...STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: iXpressGenes, Inc. Topic: NIGMS
DESCRIPTION (provided by applicant): Crystallization, followed by subsequent structure determination, is a major step in understanding the structure- function relationship of macromolecules. Understanding macromolecule structure has become a key part in the development of new pharmaceuticals, and is a major area of NIH research. Crystallization however is also the rate limiting step, despite techn ...STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: AFASCI, INC. Topic: NHLBI
DESCRIPTION (provided by applicant): Sleep deprivation (SD) occurs universally in modern societies and causes significant social and financial harm. Numerous human and animal studies indicate that various forms of SD are deleterious to mental and physicalhealth. Therefore, SD has been recognized as an unmet challenge to public health. There is increased need to study the effects of different forms ...STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: VALA SCIENCES, INC. Topic: NHLBI
DESCRIPTION (provided by applicant): Monitoring physiology of individual cardiomyocytes in high throughput has not been reported. The inability to perform high throughput physiological measurements limits many basic and applied studies, including the use of stem cell derived cardiomycoytes in cardiotoxicity testing. Current automated cardiotoxicity tests have poor predictive value because they use ...STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: WEST FACE MEDICAL DEVICES, INC. Topic: NIBIB
DESCRIPTION provided by applicant This Phase I STTR Grant Proposal requests $ support for WestFace Medical Device to construct and test the WestFace Imaging Adaptor in conjunction with Ruikang K Wang PhD and his laboratory at the University of Washington Utilizing optical coherence tomography OCT the patented OCT Adaptor USPTO Pats provides r ...STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
SBC: ELGAVISH PARAMAGNETICS, INC. Topic: NHLBI
DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
SBC: POLARONYX INC Topic: DHP15B002
Based on our success in developing the world first commercial high energy femtosecond fiber laser system and our leading proprietary technology development in ultrashort pulsed fiber laser material processing, PolarOnyx proposes, for the first time, a compact high energy fiber laser based smart wound healing tool to meet with the requirement of this DHP solicitation. It includes a high energy fs f ...STTR Phase I 2016 Department of DefenseDefense Health Agency
SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION Topic: N
DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
Use of Highly Porous Polymer Beads to Remove Anti-A and Anti-B Antibodies from Plasma for TransfusionSBC: CYTOSORBENTS MEDICAL INC Topic: DHP15B001
The ready availability of universal donor plasma to rapidly treat massively bleeding hospital trauma patients and warfighters with combat casualties is a key element of current recommendations for trauma resuscitation, yet universal AB donor plasma is relSTTR Phase I 2016 Department of DefenseDefense Health Agency