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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A NEW INSTRUMENT FOR BIOMEDICAL RESEARCH

    SBC: Microcal, Inc.            Topic: N/A

    BECAUSE OF THEIR EXTREME IMPORTANCE AND PREVALENCE IN NEARLY ALL BIOLOGICAL PROCESSES, MOST INDUSTRIAL AND ACADEMIC LABORATORIES ARE INVOLVED IN SOME WAY IN THE CHARACTERIZATION OF LIGAND-MACROMOLECULE OR MACROMOLECULE-MACROMOLECULE BINDING REACTIONS. UP TO THE PRESENT, THE MEASUREMENT OF EQUILIBRIUM CONSTANTS FOR THE DISSOCIATION OF SUCH COMPLEXES HAS USUALLY REQUIRED THE USE OF INCONVENIENT, TIM ...

    SBIR Phase II 1986 Department of Health and Human Services
  2. THE ULTIMATE GOAL OF THIS PROJECT IS TO DEVELOP A METHOD FORCARRYING OUT URODYNAMIC BEHAVIOR TESTS BASED ON CONTINUAL MONITORING OVER A PROLONGED PERIOD OF TIME THAT INCLUDES ROUTINE DAILY ACTIVITIES.

    SBC: Moco, Inc.            Topic: N/A

    THE ULTIMATE GOAL OF THIS PROJECT IS TO DEVELOP A METHOD FORCARRYING OUT URODYNAMIC BEHAVIOR TESTS BASED ON CONTINUAL MONITORING OVER A PROLONGED PERIOD OF TIME THAT INCLUDES ROUTINE DAILY ACTIVITIES. THE SPECIFIC AIMS ARE TO DEVELOP A PORTABLE MONITORING SYSTEM ATTACHED TO THE PATIENT THAT CAN RECORD PHYSIOLOGICAL DATA OVER A 24-HOUR PERIOD AND TO IMPLEMENT AUTOMATED METHODS FOR ANALYZING THE REC ...

    SBIR Phase I 1986 Department of Health and Human Services
  3. IMPROVED BLOOD SAMPLING AND ANALYSIS

    SBC: Moleculon Research Corp            Topic: N/A

    THIS PHASE I PROGRAM IS DIRECTED TOWARD ASPECTS OF CLINICAL BLOOD ANALYSIS WHICH HAVE MADE LITTLE PROGRESS IN RECENT YEARS: SAMPLE COLLECTION, PREPARATION, AND COLORIMETRY. MOLECULON WILL SEEK TO INCORPORATE AUTOMATIC MEMBRANE FILTRATION DIRECTLY INTO DISPOSABLE BLOOD SAMPLERS TO OBTAIN CELL-FREE EXTRACTS WITHOUT CENTRIFUGATION, AND WILL INVESTIGATE THE FEASIBILITY OF FURTHER LABOR SAVINGS BASED O ...

    SBIR Phase II 1986 Department of Health and Human Services
  4. ALTHOUGH TWO-DIMENSIONAL ELECTROPHORESIS HAS PROVEN TO BE A POWERFUL TECHNIQUE FOR SEPARATING AND IDENTIFYING PROTEINS IN COMPLEX MIXTURES, THE AVAILABILITY OF SUITABLE GRADIENT GELS LIMITS THE UTILITY OF THIS TECHNIQUE AND INVOLVES CONSIDERABLE

    SBC: Moleculon Research Corp            Topic: N/A

    ALTHOUGH TWO-DIMENSIONAL ELECTROPHORESIS HAS PROVEN TO BE A POWERFUL TECHNIQUE FOR SEPARATING AND IDENTIFYING PROTEINS IN COMPLEX MIXTURES, THE AVAILABILITY OF SUITABLE GRADIENT GELS LIMITS THE UTILITY OF THIS TECHNIQUE AND INVOLVES CONSIDERABLE TIME-CONSUMING HANDWORK. AN ADDITIONAL PROBLEMSTEMS FROM THE LACK OF ADEQUATE SEPARATION OF LOW MOLECULAR WEIGHT COMPOUNDS (

    SBIR Phase I 1986 Department of Health and Human Services
  5. AUTOMATED IN VITRO CYTOTOXICITY MEASUREMENT

    SBC: Optra, Inc.            Topic: N/A

    THE PROPOSED RESEARCH IS DIRECTED TOWARDS THE DEVELOPMENT OF INSTRUMENTATION AND METHODS WHICH WILL PROVIDE A RAPID, SIMPLE, STANDARDIZED SYSTEM FOR ASSESSING IN VITRO CYTOTOXICOLOGICAL EFFECTS. STANDARDIZED SYSTEMS ARE NECESSARY IF THE SIGNIFICANT ECONOMIC AND TECHNICAL ADVANTAGES OF TOXICITY TESTS ARE TO BE REALIZED. IN PHASE I OF THE PROPOSED PROGRAM, WE WILL DEVELOP OPTICAL MEASUREMENT TECHNIQ ...

    SBIR Phase II 1986 Department of Health and Human Services
  6. COMPUTER-AIDED DENTISTRY

    SBC: FOSTER-MILLER, INC.            Topic: N/A

    N/A

    SBIR Phase I 1986 Department of Health and Human Services
  7. CRY ANALYSIS AS A SCREENING TEST FOR SIDS AND HANDICAP

    SBC: Pds, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1986 Department of Health and Human Services
  8. ACOUSTIC MONITOR FOR KIDNEY/GALLSTONE BREAKUP BY LASERS

    SBC: Physical Sciences Inc.            Topic: N/A

    N/A

    SBIR Phase I 1986 Department of Health and Human Services
  9. THE NATURE OF THE ADENOSINE RECEPTOR WILL BE STUDIED USING ADENOSINE AGONISTS AND ANTAGONISTS MODIFIED FOR SELECTIVITY AND POSSIBLE AFFINITY LABELING.

    SBC: Research Biochemicals,            Topic: N/A

    THE NATURE OF THE ADENOSINE RECEPTOR WILL BE STUDIED USING ADENOSINE AGONISTS AND ANTAGONISTS MODIFIED FOR SELECTIVITY AND POSSIBLE AFFINITY LABELING. ADENOSINE PLAYS A KEY ROLE IN PHYSIOLOGICAL PROCESSES, AND CURRENTLY NO SELECTIVE A1 ORA2 ANTAGONISTS HAVE AS YET BEEN DEVELOPED. SELECTIVE AGONISTS AND ANTAGONISTS FOR ADENOSINE RECEPTORS COULD HAVE CLINICAL IMPORTANCE IN THE TREATMENT OF ASTHMA, A ...

    SBIR Phase I 1986 Department of Health and Human Services
  10. A NOVEL ACCELERATOR FOR RADIOISOTOPE PRODUCTION FOR PET

    SBC: SCIENCE RESEARCH LABORATORY, INC            Topic: N/A

    N/A

    SBIR Phase I 1986 Department of Health and Human Services

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