Award Data

“Ocean Energy Extraction for Sensor Applications” has applications on buoy systems to be used by the United States Navy to increase situational awareness and battle-group integration by enabling power independent data acquisition and distributed sensor networks. Electro Standards Laboratories proposes to meet the requirements with mechanical wave energy extraction accomplished using integrated ...

The principal objective of the proposed Phase I SBIR project is the development of a reliable predictive capability for the evaluation of flaw tolerance in metallic and composite airframe components, given part specifications, material properties, initial flaws, such as voids, inclusions, heterogeneous grain structure and design load spectra. The proposed concept is based on the idea that the saf ...

DESCRIPTION (provided by applicant): Type 1 (juvenile) diabetes is an organ-specific autoimmune disease resulting from destruction of insulinproducing pancreatic beta-cells. In non-diabetics, islet cell antigen-specific T cells are either deleted in thymic development or are converted to T regulatory cells that actively suppress effector responses to islet cell antigens. In juvenile diabetics and ...

This Small Business Technology Transfer Phase I project focuses on lameness which is one of the most common health problems for horses. Treatment is most effective in the earliest stages of lameness, however the subjective diagnostic methods currently used by large animal are imprecise and inaccurate. To improve the quality of lameness evaluation, the startup company Equinosis is leversaging resea ...

This Small Business Innovation Research (SBIR) Phase I research project aims to improve the frequency of homologous recombination by increasing the number of targeting vector molecules that reach the nucleus. The technology is based on constructing targeting vectors that have proteins involved in nuclear translocation attached. Recombination events that can target an exogenous DNA constructs to ...

IconoPsych Care, LLC is working toward commercialization of web-based mental health services which integrate the practice of video telepsychiatry with electronic medical record keeping. This research and development effort is in response to three problems: 1) the shortage of mental health providers available in rural areas , 3) stigma related to seeking mental health services, 3) the need for medi ...

DESCRIPTION (provided by applicant): One of the most expensive aspects of a cryopreservation program is related to ongoing, long-term storage and shipping of samples at very low temperatures (typically between - 196oC, the temperature of liquid nitrogen (L N2), and approximately -120oC, in the high- end temperature range of LN2 vapor). Current approaches to cryopreserving most cells and tissues, i ...

MO-SCI Corporation and the Missouri University of Science & Technology (MST-formerly University of Missouri-Rolla) propose to develop low cost, IR retro-reflective (800 nm - 2800 nm), visible absorbing glass microspheres for ubiquitous spectroscopic tagging through our innovative material design, fabrication and characterization technologies. These glass microspheres of any size (e.g., 20 - 100 mi ...

In this Phase I SBIR contract, Nanoparticle Biochem Inc (NBI) proposes to develop commercially viable synthetic methodology for the production of multifunctional gold Nanoparticle-bombesin conjugate. Gold Nanoparticle-bombesin (AuNP-BBN) conjugate is a potential clinical imaging and therapeutic agent for the detection and treatment of GRP receptors over-expressing prostate and breast cancers. Aver ...

The objective of this proposal is to develop nanoparticulate therapeutic products from the readily injectable Gold-198 (Au-198) nanoconstructs invented at the University of Missouri and licensed to Nanoparticle Biochem, Inc. The Phase I effort embodies three aims: (1) Optimization of synthetic protocols, large scale production, and quality control capabilities of Au-198 nanoparticles (NP) and thei ...