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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Software for Dynamic Behavioral Outcomes PORTAL and Dashboard

    SBC: Health Outcomes Inc            Topic: 104

    DESCRIPTION provided by applicant In his directorandapos s blog Dr Insel Director of NIMH described new directions for research andquot W e need to stop thinking about moving research to practice and start thinking about moving practice to research The idea is simple understand what works in the real world of practice by using scientific methods like randomization and statistical comp ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. e Unstuck Interactive e learning software for parents to support executive functioning and behavior regulation in children with Autism Spectrum Disorder

    SBC: 3-C Institute for Social Development, Inc.            Topic: 103

    DESCRIPTION provided by applicant The current prevalence of Autism Spectrum Disorder is in children and of these children do not have an intellectual disability ASDwoID Individuals with ASDwoID are at considerable risk for maladaptive adult outcomes e g un or underemployment and executive functioning EF impairments significantly contribute to this risk Unstuck and On Targe ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Enhancing Research Capacity via Developmentally Appropriate Online Data Collection System

    SBC: 3-C Institute for Social Development, Inc.            Topic: 100

    DESCRIPTION provided by applicant Data collection for clinical behavioral and social research has traditionally been accomplished via paper and pencil forms collected in person by telephone or through the mail however recent technological advances have resulted in a multitude of online data collection systems DCS that deploy measures and collect data online More than of all data co ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Simple Self Contained Self Sterilizing Bag

    SBC: Brighton Development            Topic: NCATS

    DESCRIPTION provided by applicant The safe and simple self sterilizing pouch system with its INNOVATIVE sterilant releasing plastic insert is ideal for STERILIZATION of all medical items especially heat and moisture sensitive medical products The product has numerous applications both commercially as well as hospital and in home healthcare applications Virtually any heat source can be use ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Nomethiazoles harnessing GABA and NO mimetic activity for Alzheimer s therapy

    SBC: sGC Pharma Inc.            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD occurs in one out of eight Americans of age and affects of the elderly over Current FDA approved drugs provide short term symptomatic relief of AD There is a pressing need to discover new disease modifying medications AD is multifactorial in origin and progression A drug attenuating several underlying factors is a p ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A noninvasive method for tissue stiffness quantification in small animals with shear wave elastography

    SBC: Sonovol, Inc.            Topic: NIDDK

    Abstract Liver fibrosis a hallmark of many liver diseases affects millions of people in America every year and annually kills tens of thousands of these patients Despite very active research efforts there still have been no specific antifibrotic drugs approved by the FDA The liver disease and drug development communities do not currently have well validated low cost easy to use noninvasiv ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Low cost retinal optical coherence tomography for point of care use

    SBC: Lumedica, Inc            Topic: NEI

    DESCRIPTION provided by applicant The objective of this research is to create a clinical prototype of a new optical coherence tomography OCT system for use in point of care settings The target system price will be one third the price of currently available research OCT system while providing system performance comparable to other entry level OCT imaging systems By breaking the $ syste ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Identification of Novel Small Molecule AMPK Modulators

    SBC: CurlBio LLC            Topic: 200

    Western life style has spurred the growth of numerous obesity related disorders including metabolic syndrome type diabetes and non alcoholic fatty liver disease NAFLD to epidemic proportions Maintaining cellular energy is a basic biological need mediated in part through amp activated protein kinase AMPK therefore controlling cellular energy metabolism can play a role in treating metabolis ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Unique Antimicrobial Catheter to Prevent Urinary Tract Infections

    SBC: Brighton Development            Topic: 400

    The goal of this Phase II effort is bring to market a unique antimicrobial catheter to reduce the instances of the most prevalent healthcare associated infection Catheter Associated Urinary Tract Infection CAUTI This research and development effort will be to develop a urinary catheter with inherent long lasting antiseptic properties to protect the patient and prevent infection We have begun ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development and validation of a human brown adipocyte system

    SBC: ZEN-BIO, INC.            Topic: 200

    Project Summary The activation and recruitment of brown adipose tissue has become an exciting target in the fight against obesity and its related metabolic diseases Brown adipose tissue differs from white adipose tissue in its critical ability to burn energy as heat through UCP driven adaptive thermogenesis Expression of mitochondrial UCP uncouples oxidative phosphorylation resulting in acc ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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