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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Enhanced production of human hepatocytes from livers declined for transplant

    SBC: HEPATOSYS INC            Topic: 300

    DESCRIPTION provided by applicant Liver toxicity is a major barrier to the FDA approval of many new drugs Moreover since the liver is the major site of metabolism of most xenobiotics it is essential to know how the liver metabolizes a potential new drug Because of the many species differences between humans and commonly used animal models testing on human hepatocytes remains the gold stand ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Point-of-Care Nitric Oxide Sensor for Wound Management

    SBC: CLINICAL SENSORS, INC.            Topic: 300

    DESCRIPTION provided by applicant This Small Business Innovation Research SBIR Phase I project aims to develop a microfluidic based nitric oxide NO sensor to prospectively identify wounds that are unlikely to heal Each year over million Americans develop chronic wounds such as pressure ulcers and diabetic foot ulcers In the U S alone the high prevalence of chronic wounds is a $ bil ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Histone phosphorylation-dependent screening platform for identification of inhibitors to treat neuroblastoma

    SBC: Epicypher, Inc.            Topic: 300

    Project Summary In this proposal we will develop a synthetic nucleosome based drug screening platform to identify novel therapeutics to treat neuroblastoma Histone acetylation is associated with gene activation and is catalyzed by histone acetyltransferase enzymes HATs Histone hyperacetylation is a key driver of neuroblastoma Several recent studies demonstrate that inhibition of HAT activi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Low cost retinal optical coherence tomography for point of care use

    SBC: Lumedica, Inc            Topic: NEI

    DESCRIPTION provided by applicant The objective of this research is to create a clinical prototype of a new optical coherence tomography OCT system for use in point of care settings The target system price will be one third the price of currently available research OCT system while providing system performance comparable to other entry level OCT imaging systems By breaking the $ syste ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Web-based High School Media Literacy for Healthy Relationships

    SBC: Innovation Research And Training, Inc.            Topic: NICHD

    Project Abstract The rates of HIV AIDS other STIs unplanned pregnancies and dating violence among adolescents indicate the need for evidence based medically accurate comprehensive sexual health education However both teachers and parents face challenges in effectively teaching about sexual health and relationships leading to students receiving incomplete or inaccurate information Young peo ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Novel technologies for the detection of podocytes from preeclamptic patients

    SBC: AFFINERGY, LLC            Topic: NICHD

    SUMMARY ABSTRACT Preeclampsia is a complication of pregnancy characterized by elevated blood pressure proteinuria and endothelial dysfunction involving multiple organ systems Worldwide preeclampsia is the largest cause of fetal and maternal morbidity and mortality and accounts for nearly of maternal deaths in the United States alone each year Currently there is no approved diagnostic te ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Clinical evaluation of the novel, uni-directional, Pd-103 CivaSheet for Pancreatic Cancers

    SBC: CIVATECH ONCOLOGY INC            Topic: 102

    CivaTech Oncology s mission is to provide improved radiation therapy directly to localized tumors The Company has developed a novel polymer encapsulated membrane like radiation source that emits radiation on only one side of the device the CivaSheet This directional source is compatible with open and minimally invasive surgical techniques and has FDA clearance to be used as primary or combin ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Identification of Novel Small Molecule AMPK Modulators

    SBC: CurlBio LLC            Topic: 200

    Western life style has spurred the growth of numerous obesity related disorders including metabolic syndrome type diabetes and non alcoholic fatty liver disease NAFLD to epidemic proportions Maintaining cellular energy is a basic biological need mediated in part through amp activated protein kinase AMPK therefore controlling cellular energy metabolism can play a role in treating metabolis ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Unique Antimicrobial Catheter to Prevent Urinary Tract Infections

    SBC: Brighton Development            Topic: 400

    The goal of this Phase II effort is bring to market a unique antimicrobial catheter to reduce the instances of the most prevalent healthcare associated infection Catheter Associated Urinary Tract Infection CAUTI This research and development effort will be to develop a urinary catheter with inherent long lasting antiseptic properties to protect the patient and prevent infection We have begun ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development and validation of a human brown adipocyte system

    SBC: Zen-Bio, Inc.            Topic: 200

    Project Summary The activation and recruitment of brown adipose tissue has become an exciting target in the fight against obesity and its related metabolic diseases Brown adipose tissue differs from white adipose tissue in its critical ability to burn energy as heat through UCP driven adaptive thermogenesis Expression of mitochondrial UCP uncouples oxidative phosphorylation resulting in acc ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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