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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Feasibility of Using a High-speed AI-driven Experimental Platform to Develop an Optimized DNA Template for Cell-free Protein Expression

    SBC: BigHat Biosciences, Inc.            Topic: 90

    We propose to demonstrate the feasibility of using a high-speed artificial intelligence (AI)-driven experimental platformto optimize the DNA template for cell-free protein synthesis (CFPS) to maximize protein expression. Our platform isdesigned to rapidly find an optimal DNA sequence among millions of possible sequences through repeated designbuild-test cycles: AI is used to design the DNA templat ...

    SBIR Phase I 2020 Department of CommerceNational Institute of Standards and Technology
  2. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: QATCH TECHNOLOGIES LLC            Topic: 90

    The main focus of this SBIR Phase II project is to develop a prototype instrument and test cartridges for injectability pre-screening of high concentration protein formulations (HCFs). HCFs are non-Newtonian fluids with shear-thinning behavior and they are formulated to be administered by subcutaneous or muscular injections. The injectability and manufacturability of HCFs depend on the viscosity b ...

    SBIR Phase II 2020 Department of CommerceNational Institute of Standards and Technology
  3. High Throughput, High-Pressure Small-Angle Neutron Scattering Sample Environment

    SBC: STF TECHNOLOGIES LLC            Topic: 90

    We address a need of the neutron user community by creating a minimum viable prototype of the only high-throughput hydrostatic pressure small angle neutron scattering sample environment (HTHP-SANS-SE). Our HTHP-SANS-SE will greatly improve the ease of use and reliability of measurements under extreme environments, thereby increasing throughput on the beamline and expanding feasibility. Current HP- ...

    SBIR Phase I 2020 Department of CommerceNational Institute of Standards and Technology
  4. Advanced Instrumentation for Non-Nulling Stack Velocity Testing

    SBC: AIRFLOW SCIENCES CORP            Topic: 90

    Industrial facilities, manufacturing plants, and electric power plants that burn fossil fuels exhaust the combustion products to atmosphere through their smokestacks. Stack pollutant emissions are quantified using manual testing methods developed in the 1960s, which are prone to error if complex flow patterns exist, which is common. Recently, NIST has been working on an improved technique of perfo ...

    SBIR Phase II 2020 Department of CommerceNational Institute of Standards and Technology
  5. Advanced Measurement Probe System for Non-Nulling Velocity Testing

    SBC: AIRFLOW SCIENCES CORP            Topic: 90

    Industrial facilities and power plants that burn fossil fuels exhaust the combustion products to atmosphere through their smokestacks. Stack pollutant emissions are quantified using manual testing method developed in the 1960s, which are prone to error due to biases from human operators and any non-axial flow in a stack.NIST has been working on an improved technique of performing 3D flow testing f ...

    SBIR Phase I 2020 Department of CommerceNational Institute of Standards and Technology
  6. Continuous Monitoring of Natural Gas Infrastructure for Increased Community Resilience using Voltammetric Sensors

    SBC: FULLMOON SENSORS, INC.            Topic: None

    Fullmoon has the first chip-level sensors capable of identifying and quantifying molecules in the air. At the core of our technology are printed voltammetric sensors, which are operated using cyclic voltammetry, an electrochemical technique that probes for the redox potential, a unique signature of molecules. We have demonstrated this sensing principle for the detection of carbon monoxide and meth ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  7. Developing Commercial Quantum Resistance Standard Based on Epitaxial Graphene

    SBC: GRAPHENE WAVES, LLC            Topic: None

    Graphene Waves proposes to develop a quantum Hall resistance (QHR) standard based on graphene that can be deployed for general electrical calibration in industries. Current QHR standard is based on GaAs/AlGaAs heterostructure and requires expensive liquid helium to operate. The continuous increase in price and unstable supply chain of liquid helium limit the QHR standard to be only affordable by t ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  8. A Portable Vibrio Cholerae Concentrator for Sensitive Pathogen Detection in Water

    SBC: OMNIVIS INC            Topic: None

    This SBIR Phase I project proposes to develop an easy to use, inexpensive, and portable bacterial concentrator to enable more sensitive cholera pathogen (Vibrio cholerae) detection. Cholera affects communities across 41 countries, including Mozambique in 2019 after Cyclone Idai and Yemen in 2017. Current methods used to detect the cholera pathogen in water involves a 3 to 5-day procedure due to th ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  9. Laser Particle Separation

    SBC: Opthos Instrument Company, LLC            Topic: None

    Parman Tech is dedicated to commercializing a NIST technology for sorting nano-particles. This technology uses the force of light to gently guide particles along different paths depending on the size of makeup of each particle.

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  10. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: QATCH TECHNOLOGIES LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
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