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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. DESCRIPTION (provided by applicant): Sexual violence perpetrated against women is a serious public health problem. Among female adolescents rates as high as 53% for some types of sexual violence have been reported. Moreover, young women are assaulted or r

    SBC: BT POST            Topic: NCIPC

    DESCRIPTION (provided by applicant): Sexual violence perpetrated against women is a serious public health problem. Among female adolescents rates as high as 53% for some types of sexual violence have been reported. Moreover, young women are assaulted or raped most often by someone they know and often alcohol is a contributing factor. Thus, there is a need for effective and innovative primary preve ...

    SBIR Phase I 2010 Department of Health and Human Services
  2. Novel DNA Polymerase Inhibitors as Gram-Positive Antibacterial Agents

    SBC: CRESTONE, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The alarming increase in incidence of infections caused by drug-resistant bacteria has created an urgent need for new antibacterial agents. We have discovered and optimized a novel class of antibiotics targeting PolC, the replicative DNA polymerase in Gram-positive bacteria. These agents exhibit broad spectrum activity against Gram-positive bacteria, including ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. A Patient-Centered Approach to Enrolling Rare Cancer Patients in Clinical Trials

    SBC: PHARMATECH, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Our new president vows to address the pervasive issue of cancer. Over 1.4 million Americans will be diagnosed with cancer this year, joining over 10 million living Americans who have experienced cancer. The medical costs of cancer care were 78 billion in 2008, and the overall economic impact was estimated to be over 200 billion. The current administration pl ...

    SBIR Phase I 2010 Department of Health and Human Services
  4. Real Time Visualization of Clot under X-Ray Using 'Clot-Paint', a Novel Iodinated

    SBC: BIOPSY SCIENCES, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Biopsy Sciences, LLC NIH SBIR Phase I Grant Application Real Time Visualization of Clot under X-Ray Using Clot-Paint , a Novel Iodinated Protein Receptor Bound Molecule Project Summary/Abstract There are over 750,000 new cases of stroke in the U.S. each year. Of those suffering a major stroke, one-third will recover, one-third will die and one-third will be p ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Process for Removal of Microcontaminants from Municipal Water

    SBC: ELTRON RESEARCH & DEVELOPMENT, INCORPORATED            Topic: NIEHS

    DESCRIPTION (provided by applicant): It has been found that pharmaceuticals and over-the-counter medicines are present in drinking water supplied to at least 41 million Americans. Concern exists over the long-term health effects that will result from inges ting antibiotics, anticonvulsants, mood stabilizers, sex hormones and other drugs. Gender-reversal of fish living in municipal water containing as low as five parts per trillion of estradiol is one of the more shocking examples of documented effects.

    SBIR Phase I 2010 Department of Health and Human Services
  6. RAPID, LABEL-FREE AND MULTIPLEX DETECTION OF MICRORNAs

    SBC: BIOPTIX DIAGNOSTICS, INC.            Topic: NCI

    This SBIR Phase I project will evaluate an ultra-sensitive detection technology known as Surface Plasmon Enhanced Common Path Interferometry (SPE-CPI) in the rapid, label-free identification and quantification of cancer-related microRNAs in blood samples. MicroRNAs have gained considerable attention as potentially predictive biomarkers for a number of disorders. Mounting evidence suggests that miR ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Rapid, Label-free, Multiplex Detection of MicroRNAs

    SBC: BIOPTIX DIAGNOSTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Minimally invasive tests for the detection and monitoring of malignancies are urgently needed worldwide to reduce the morbidity and mortality caused by cancer. While promising, blood-based proteonomic assays have yet to be clinically validated for many common human cancers. Accordingly, new approaches are being investigated that will likely complement or improv ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Conversations About Cancer (CAC): A Theatrical Production

    SBC: KLEIN BUENDEL, INC            Topic: NCI

    DESCRIPTION (provided by applicant): Over the past decade, an investigation of how family members talk through cancer on the telephone has resulted in the recent publication of a lengthy volume entitled A Natural History of Family Cancer: Interactional Resources for Managing Illness (NH). Based on the conversations analyzed for this volume, and related research on the psychosocial impacts and con ...

    STTR Phase I 2010 Department of Health and Human Services
  9. Automated Head Turn Tracking and Other Innovations for VRA

    SBC: Intelligent Hearing Systems Corp.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The overall goal of this study is to develop a head tracking procedure for the automated assessment of hearing in infants using Visual Reinforcement Audiometry (VRA). The head tracking procedure will be incorporated into the Intelligent Visual Reinforcement Audiometry (IVRA) system from Intelligent Hearing Systems Corp. The IVRA system currently provides automa ...

    STTR Phase I 2010 Department of Health and Human Services
  10. Dynamic facial soft tissue analysis system

    SBC: 3DMD, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): The primary goal of this Fast Track STTR application is to develop a 4D facial analysis system for both static and dynamic analyses that will utilize high resolution 3D cameras to acquire patient-specific facial shape information along with software that will be user- friendly, low-cost, and provide fast quantitative analyses. Target applications are wide- rang ...

    STTR Phase I 2010 Department of Health and Human Services

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