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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Novel Screen Approach to Inactivate Whole Viral Vaccines by Supralethal Irradiation

    SBC: AGAVE BIOSYSTEMS INC.            Topic: DTRA14B002

    Future vaccine development should focus on rapid upscale production, long-term and broad protection, and sufficient global distribution to prevent and reduce the impact of many infectious diseases and potential epidemics. Agave BioSystems proposes to develop a novel whole-microorganism vaccine inactivation strategy involving high-throughput screen of extensive radio-protectant matrices and radiati ...

    STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency
  2. Automated Assessment of Leptomeningeal Collaterals on CT Angiograms

    SBC: Kitware, Inc.            Topic: 108

    DESCRIPTION provided by applicant The primary goal of this study is to develop an automated scoring system of leptomeningeal collaterals based on CT angiography CTA as a quantitative assessment of acute stroke Leptomeningeal collaterals provide an alternate path of blood flow in the setting of a proximal occlusion The presence and effectiveness of leptomeningeal collaterals i e andquot c ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Ultrasound Based Device to Guide Treatment of Graft Versus Host Disease Using Skin Elasticity as a Biomarker

    SBC: Microelastic Ultrasound Systems, Inc.            Topic: 102

    Ultrasound Based Device to Guide Treatment of Graft Versus Host Disease using Skin Elasticity as a Biomarker ABSTRACT Sclerotic chronic graft versus host disease cGVHD develops in of allogenic Human Stem Cell Transplant HCT recipients and is associated with significant morbidity and mortality GVHD is treated with immunosuppression which puts patients at severe risk of infection ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Science Take-Out Kits for Improving Environmental Health Literacy on Vaping

    SBC: Science Take-Out, LLC            Topic: NIEHS

    ABSTRACT E cigarettes are currently the most commonly used tobacco product among youthand they are typically marketed to youth by promoting flavorsCommonly cited reasons for e cigarette usevapingamong both youth and young adults are flavoring taste and low perceived harm compared to other tobacco productsBecause of the rapidly evolving e cigarette technologythere are many uncertainties and unknown ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Innovative Tools for Three Dimensional Traction Force Microscopy of Single Cells

    SBC: SIMMETRIX INC.            Topic: 102

    Project Summary Tractions exerted by individual cells on their surroundings play a critical role in mechanical events in biology such as tissue contraction folding cell shape changes or cell movements and in many basic cellular functions such as biochemical signaling proliferation and differentiation These processes are in turn implicated in the progression of diseases like cancer atherosc ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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