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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Asthmagram: objective assessment of asthma symptoms in children

    SBC: NeoVative, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Asthma is the most common chronic illness of childhood but many children have poorly controlled symptoms causing morbidities hospitalizations and costs The first step toward good asthma control is accurate assessment of symptoms Recall of the frequency and severity of symptoms is the cornerstone of asthma assessment Unfortunately recall by parents or ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Measuring Bladder Permeability with MRI using a Novel Contrast Agent Formulation

    SBC: Lipella Pharmaceuticals Inc.            Topic: 400

    DESCRIPTION provided by applicant This project entails the development of a novel dual component MRI contrast agent formulation for the detecting permeability in the luminal surface of the urinary bladder The purpose of having such a test is ultimately to allow clinicians in certain circumstances to differentially diagnose a chronic non infectious inflammation of the urinary bladder from a ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Paper-based Rapid Diagnostics for Early Dental Caries Prediction at the Chairside

    SBC: PHASE DIAGNOSTICS LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Dental caries is the single most common affliction across the globe affecting billion people The current process of identifying dental caries involves examining caries formation by naked eyes or X ray during routine checkups Once identified surgical restorative procedures are used to drill out the decay portion of the tooth an filled with synthetic mate ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Scientific Merit and Feasibility of Fructokinase Inhibiton for Obesity

    SBC: COLORADO RESEARCH PARTNERS LLC            Topic: NIDDK

    DESCRIPTION provided by applicant Intake of added sweeteners high fructose corn syrup and sucrose independently predicts the development of obesity metabolic syndrome and diabetes Despite recommendations by WHO and the AHA to reduce sugar intake to to percent of total energy intake the mean intake of added sugars remains percent of the diet and percent of the population ingest ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A new treatment for NSAID-associated gastrointestinal damage

    SBC: Anteana Therapeutics Inc            Topic: NIDDK

    DESCRIPTION provided by applicant Non steroidal anti inflammatory drugs NSAIDs are among the most widely consumed pharmaceuticals but their prolonged use causes gastric injury and damage to the small intestine Previous work has shown that anandamide an endogenous endocannabinoid substance produced in the gastrointestinal GI mucosa plays an important role in epithelial homeostasis and re ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. A high-throughput kit for detection of RNA modifications

    SBC: MAVERIX BIOMICS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant The broad objective of this project is to develop an integrated wet lab dry lab kit for high throughput detection of RNA modifications The final product will provide all required molecular biology reagents a set of simple and robust experimental manipulations for facile analysis of modifications and researcher friendly analytic cloud based software requi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Novel mass spectrometry methods for profiling modified RNA nucleotides in the nervous system

    SBC: Ribonova Inc.            Topic: NIDA

    DESCRIPTION provided by applicant Pseudouridine is the most abundant post transcriptionally modified nucleoside found in ribonucleic acid RNA Pseudouridine is an enzymatically generated isomer of the canonical base uridine with additional hydrogen bonding capabilities and appears to lead to local structural and biochemical effects within RNAs Pseudouridine has been detected in several type ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Interactive technology for media literacy drug prevention in community groups

    SBC: REAL PREVENTION LLC            Topic: R41

    DESCRIPTION provided by applicant The goal of this STTR R proposal is to transfer the technology from Rutgers University to REAL Prevention needed to adapt a substance use prevention media literacy curriculum for web based delivery in community organizations for commercialization Substance use increases in frequency and risk through mid adolescence yet most prevention interventions target ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a biomimetic small molecule therapeutic for neovascular retinal diseases

    SBC: EyeMedix, Inc.            Topic: N

    DESCRIPTION provided by applicant Retinal diseases including age related macular degeneration AMD diabetic retinopathy DR diabetic macular edema DME and retina vein occlusion RVO are the leading causes of vision loss and blindness in people over years old According to the NEI in nearly million people in the U S suffered from some form of these diseases whose prevalen ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. A Visual Assessment System for Retinal Function/Drug Discovery

    SBC: AFASCI, INC.            Topic: N

    DESCRIPTION provided by applicant Preclinical evaluation of treatment strategies for retinal neurodegenerative diseases is highly dependent on mouse models Classical methods to assess the visual function of animals such as electroretinogram ERG which measures electrical responses in the retina do not address connections between the eye and brain or visual perception by the visual system ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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