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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improving Outcomes for Mechanically Ventilated Patients with the Digital EZ Board

    SBC: VIDATAK, LLC            Topic: 600

    DESCRIPTION provided by applicant Effective communication between patients and healthcare professionals is essential to achieve positive clinical outcomes Patients who are unable to communicate effectively e g patients with limited English proficiency LEP those who are hearing impaired aphasic or have oral tracheal intubation experience extreme frustration panic anxiety sleeplessne ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a 3D Intra-oral X-ray Imaging System

    SBC: Turner Innovations L.C.            Topic: NIDCR

    DESCRIPTION provided by applicant Turner Innovations proposes to develop a D intra oral x ray imaging system for use in dental clinics Current D radiographs are often ambiguous for caries detection are not usually able to visualize fractures in a tooth and because they are plane projections they can miss tooth curvature and other anomalies important to dental diagnosis and treatment Cone ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Needle-implantable sensor with multi-sensing elements for accurate glucose monitoring

    SBC: Biorasis            Topic: 200

    DESCRIPTION provided by applicant Over the past five years Biorasis Inc has been developing a totally implantable biosensor platform x x mm capable of continuously monitoring glucose The underlying principle in developing this miniaturized sensor hinges on extreme miniaturization utilizing light both as a powering source and a communication link Such implant size reduction res ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Therapeutic Inhibition of MIF in Type 1 Diabetes

    SBC: L2 DIAGNOSTICS LLC            Topic: 200

    DESCRIPTION provided by applicant The long term product goal of this project is a small molecule therapeutic to prevent or treat Type diabetes T D Our objective is to reduce the inflammatory response triggered by the pro inflammatory cytokine macrophage migration inhibitory factor MIF Under physiological conditions MIF is secreted by cells and regulates their function but during immu ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Development of DT-109 as an oral therapeutic for type 2 diabetes

    SBC: Diapin Therapeutics LLC            Topic: 200

    DESCRIPTION provided by applicant Type diabetes T D is chronic disease characterized by high blood glucose and rapidly emerged as a global health care problem that threatens to reach pandemic levels by Nearly million people worldwide are currently affected by diabetes Diabetes is a major cause of heart disease and stroke and also leads to other complications such as vision loss ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Novel Inhibitors of Multi-Drug-Resistant Mutants of BCR-ABL for the Treatment of Chronic Myelogenous Leukemia (CML) and Ph Positive Acute Lymphocytic Leukemia (ALL).

    SBC: HOUSEY PHARMACEUTICAL RESEARCH LAB            Topic: 102

    DESCRIPTION provided by applicant This is a Phase I SBIR Application entitled andquot Novel Inhibitors of Multi Drug Resistant Mutants of BCR ABL for the Treatment of Chronic Myelogenous Leukemia CML and Ph Acute Lymphocytic Leukemia ALL andquot The overall goal of this proposal is to further optimize and improve the efficacy of novel classes of compounds discovered developed and patent ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a Peripherally-Acting Peptidic Galanin Analog for Treatment of Postoperative Pain

    SBC: NAVIGEN, INC.            Topic: NIDA

    DESCRIPTION provided by applicant The development of non opioid analgesics for the control of postsurgical pain is widely acknowledged as an important goal The side effects of opioids most notably respiratory depression but also including sedation nausea constipation and sleep impairment make their use challenging and even potentially life threatening Of course the difficulties posed by ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Vector and strain system for the in vivo conversion of antibody fragments into IgG molecules

    SBC: AXIOMX INC            Topic: 200

    DESCRIPTION provided by applicant Current methods for converting an antibody fragment for example scFv Fab Fabandapos etc involves subcloning from an M phagemid or yeast display vector by either restriction enzyme digestion or PCR followed by ligation into or more vectors to produce the heavy and light chains transformation into E coli and subsequent DNA sequencing validation T ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Open Source Tools and Standards to Facilitate the Reuse of Electronic Data Capture Instruments in Mental Health Research

    SBC: PROMETHEUS RESEARCH, LLC            Topic: 104

    DESCRIPTION provided by applicant Electronic data capture EDC systems have increasingly replaced paper based methods of collecting mental health research data As EDC systems have proliferated however so has the number of incompatible formats for storing EDC instruments form configurations The lack of interoperability among EDC formats makes it difficult to reuse share or find previo ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. PDE4D PET Ligand for Psychiatric Disease

    SBC: Tetra Discovery Partners, Inc.            Topic: 101

    Tetra Discovery Partners is the recipient of an NIH Blueprint Neurotherapeutics Network award to develop phosphodiesterase D PDE D Negative Allosteric Modulators NAMs for treating memory loss in patients affected by psychiatric and neurologic diseases The Tetra NIH Blueprint drug is projected to reach human Phase I clinical trials in late Through a Cooperative Research and Development ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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