Award Data

For economically viable large-scale production of microalgae based food and biofuel to become a reality, significant improvements in algal productivity need to be achieved. With current regulatory guidelines, large scale outdoor cultivation of microalgae for these products restricts the use of transgenic algal strains, which in the laboratory, have thus far been the primary strategy taken to effec ...

The discovery of large shale gas reserves in recent years has resulted in the reduction of natural gas price and a need to develop new applications for the available resource. Upgrading shale gas to liquid fuels which are more easily transportable and have greater economic value can result in significant benefits to the US. Coupled with this challenging problem the DOE has a goal of further develo ...

To advance a strong and economical biofuels and bioproducts industry, tools are needed for breeding microalgae to improve phenotypes of commercial interest, including biomass yield, culture stability, harvestability, and accumulation of valuable compounds. This project aims to increase biomass feedstock yields by the phototrophic green alga Scenedesmus obliquus by using classical breeding approach ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

Society at large and DOE in particular have an interest in the continued development and refinement of a smart grid infrastructure that more efficiently and reliably matches electrical resources to demands. While technological advances in recent years have improved the smart grid, these advances have been limited by a lack of granularity of data (e.g. environmental conditions at multiple locations ...

One of grand challenges in nanoscience and nanotechnology is to achieve fundamental under- standing of the dynamic evolution of materials in actual operating environment, non-equilibrium conditions, or undergoing chemical reactions at the nanoscale. This requires forefront advances in imaging and analysis techniques that combine nanometer-scale spatial resolution, optical excitation and spectrosco ...

This project will develop a flexible longitudinal electron optical system based on high-precision radio-frequency cavities for short and intense electron bunch compressions, both in the energy and time domains. The proposed system is designed to be insertable into an existing transmission electron microscope column to upgrade its temporal resolution. Active phase-space control enables broad ranges ...

Although thermal and cold neutron scattering is widely used, and is critical for success in many areas of materials science and engineering, relatively low neutron fluxes severely limit applications of not only laboratory neutrons generators, but also large national neutron facilities. State-of-the-art thermal and cold neutron sources are large expensive national facilities, which serve diverse co ...

According to a report by the Hydrogen Council, a global lobby set up in January 2017 by Toyota and Air Liquide that includes 27 members such as automakers Audi, BMW, Daimler, Honda and Hyundai, and energy firms Shell and Total, increasing the use of hydrogen in power, transport, heat and industry could deliver around one fifth of the total carbon emissions cuts needed to limit global warming to sa ...