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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 81 - 90 of 23070 results
  1. PostureCheck: A vision-based compensatory-posture-detection tool to enhance performance of the BURT upper-extremity stroke-therapy device

    SBC: Barrett Technology, LLC            Topic: NIBIB

    SummaryAbstractThis Small Business Innovation ResearchSBIRPhase I project proposes the development of an imageprocessing based toolnamed PostureCheckaimed at automatically detecting when patients perform undesirable compensatory movements during robot assisted upper limb rehabilitation exercisesThe system will be based on a standard video camerae gGoProthat will be used to capture the movements of ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Improved Amputee Quality of Life Enabled by Tailored, Self-Regenerating Energy Storage Device For Powered Prosthetics

    SBC: Giner, Inc.            Topic: NICHD

    PROJECT SUMMARY Improved Amputee Quality of Life Enabled by TailoredSelf Regenerating Energy Storage Device forPowered Prosthetics Poweredmotorized prosthetics enable users to more naturally perform taskssuch as climbing stairs or rising from a seated positionHowever because the power requirements fluctuate during the gait cyclethe current battery system is not energy efficient and also since ener ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Generalized Change Detection to Cue Regions of Interest

    SBC: FeatureX, Inc.            Topic: NGA181006

    Generalized change detection is a critical capability to mitigate the need for massive human inspection of the rapidly expanding volume ofglobal overhead satellite imagery. Current optical change detection approaches focus on fully specified systems to detect a predefined set ofchanges, and effective approaches for generalized change detection have not yet been demonstrated. We propose to build a ...

    SBIR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
  4. Electric Propulsion for Dual Launch

    SBC: DIVERSIFIED TECHNOLOGIES, INC.            Topic: AF162009

    DTI will develop a low-cost, small size, high performance Magnetic Induction Plasma (MIP) engine enabled by advanced solid-state switching technology.We propose to design, fabricate, and test a prototype system. We will design and test an electrodeless plasma source; model electromagnetic and plasma behavior to inform design of the thruster; design high power solid-state power electronics to power ...

    SBIR Phase II 2018 Department of DefenseAir Force
  5. Variable Pressure/Flow Control Firefighting Nozzle

    SBC: ALDEN RESEARCH LABORATORY, INC.            Topic: AF171001

    The Overall objective of what will be a three phase program is to develop a hose-end nozzle system capable of allowing the operator to hand select discharges of Ultra-High Pressure (UHP; 15 to 20 GPM @ 1000 to 1400 PSI) and Low Pressure (LP; 80 to 90 GPM @ 90 to 110 PSI) water streams at variable flow rates through a single hose line and application nozzle. Phase I demonstrated the feasibility of ...

    SBIR Phase II 2018 Department of DefenseAir Force
  6. PCS-Enabled Unattended Radiation Detection and Attribution System

    SBC: Physical Sciences Inc.            Topic: HSB0171009

    Physical Sciences Inc. (PSI) proposes to develop a PCS-Enabled Unattended Radiation Detection and Attribution System (PURDAS) that will be able to detect, identify, and attribute radiological sources to specific source carriers or conveyances. The PURDAS will include a COTS gamma and neutron detection capability as well as a visible camera, onboard processing, and wireless radios. PURDAS units wil ...

    SBIR Phase II 2018 Department of Homeland SecurityDomestic Nuclear Detection Office SBIR Program
  7. Clinical Translation of a Novel Diagnostic Agent to Predict Immunotherapy Response in Solid Tumors

    SBC: CytoSite BioPharma Inc.            Topic: 102

    Over the past three years an entirely new cancer treatment paradigm has emerged following the FDA approval ofdifferent checkpoint inhibitors for a number of indications includingmetastatic melanoma and non small cell lung cancerThese new agents work by effectively releasing the brakes on the immune system that normally limit the body s natural responses to tumor cells and have generated long term ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Pressure Management Technologies for Oxygenation of Implanted Insulin Secreting Cells

    SBC: Giner, Inc.            Topic: NIDDK

    PROJECT SUMMARY Pressure Management Technologies for Oxygenation of Implanted Insulin Secreting Cells The overall goal of the SBIR project is to develop an advancedminiaturized implantable electrochemical oxygen generator that supplies oxygen at well regulated dose and concentration to cells within an immunoisolation deviceso as to ensure their viability and function at high density and minimize o ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Development of an ALDH2-Targeting RNAi Therapeutic for Alcohol Use Disorders

    SBC: Dicerna Pharmaceuticals, Inc.            Topic: 150

    Abstract Alcohol Use DisorderAUDis a chronic condition characterized by compulsive alcohol useloss of control over alcohol useand a negative emotional state when not using alcoholwith such use associated with a range of medicalpsychologicalsocialeconomicand personal problemsAUD is global and prevalentin a survey of overadults in the USAUD had amonth prevalence ofaffecting overmillion adults in the ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Droplette: A Platform Technology to Deliver Nucleic Acid Therapeutics Deep into Tissue for the Treatment of Epidermolysis Bullosa and Other Genetic Diseases

    SBC: NOVOPYXIS INC.            Topic: NIBIB

    SignificanceEffective delivery of nucleic acid therapeuticsNATis necessary for the treatment and or prevention of a myriad of genetic diseases such as Epidermolysis bullosaEBas well as for other non genetic diseasesincluding infectious diseasescancersand slow healing woundsWhile advancements have been made in the NAT fieldeffective NAT delivery remains the bottleneck for gene therapyThere are curr ...

    SBIR Phase I 2018 Department of Health and Human Services

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