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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. In vivo laryngeal imaging combining parallel OCT with videostroboscopy

    SBC: MixZon, Inc.            Topic: Y

    Project Summary AbstractThere is a constant need in the voice clinic to make effective diagnosticsurgicaland therapeutic decisions based on coupling visual judgments of vocal fold morphology and tissue motion with auditory perceptions of voice qualityCurrentlylaryngologists and speech language pathologists do not have an endoscopic imaging tool that can directly capture the three dimensionalDsurfa ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living

    SBC: BioSensics LLC            Topic: NIA

    ABSTRACT With a Phase I II STTR grant award from NIABioSensics in collaboration with Baylor College of MedicineBCMsuccessfully developed and commercialized an advanced physical activity monitoring systemPAMSysfor older adultsPAMSys enables continuous remote monitoring of physical activityfall riskand fall incidentsThe fall detection technology of PAMSys has become the gold standard in the medical ...

    STTR Phase I 2018 Department of Health and Human Services
  3. Managing Vascular Dementia Risk Factors with SymTrend

    SBC: SymTrend inc            Topic: NIA

    Project Summary AbstractAbstractDiseases of blood vessels in the brain culminate in vascular dementiaVaDand ultimately rob one of independence in activities of daily living in elder yearsThey often commence an insidious progression in early to midlife with a concomitant diminution in work proficiencyVascular dementia is treatablehoweverSuccessful containment of the progression requires rigorous ma ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. A Rapid Breath Test for Invasive Aspergillosis

    SBC: Volatylix, Inc.            Topic: NIAID

    Project Summary AbstractInvasive aspergillosisIAis a leading cause of morbidity and death in immunocompromised patientswith overmillion individuals at risk for IA and at leastIA cases developing worldwide each yearDespite the development of potent triazole antifungal drugs for the treatment of IAIA associated mortality is stillTimely and accurate diagnosis of IAin conjunction with prompt initiatio ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. A Compact Hybrid Magnet with High Homogeneity for X-Band DNP/NMR and EPR Spectroscopy

    SBC: BRIDGE 12 TECHNOLOGIES, INC.            Topic: 400

    Project SummaryAbstract We propose to develop aT compact and portable hybrid magnet with high homogeneityandltppmandT of sweep rangeThe magnet system will be used in Overhauser Dynamic Nuclear Polarization experiments in the X Band for studying water dynamics in molecules and other analytical chemistry applicationsIn Phase Iwe will designbuild and test a prototype magnet to meet the above stated r ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Designing low-cost, customizable high-density probes for acute and chronic neural recordings in rodents

    SBC: Neural Dynamics Technologies LLC            Topic: 101

    SFProject Summary Understanding how the brain generates certain behaviors requires an understanding of the function of individual neurons in dynamical neural circuitsCurrentlythere are few technologies available however that allow researchers to record both the activity within a brain regionand between brain regions in the brains of awakebehaving animalsRecent advances in microelectrode fabricatio ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Reducing the incidence of febrile neutropenia in cancer patients treated with chemotherapy with PointCheck: a portable non-invasive neutropenia analyzer

    SBC: LEUKO LABS, INC.            Topic: 396

    Every year in the UScancer patients are treated with chemotherapyAs a side effecttheir neutrophil countsnumber of white blood cells that aid in fighting infectionsbecome lowreferred to as neutropeniaand expose them to febrile neutropeniaFNwhich are episodesof serious infection that entail costly hospitalization and sometimes deathIfneutropenia is detected earlyFN can be avoided through timely deli ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Bacterial delivery of phosphatase antagonists to metastatic breast cancer

    SBC: ERNEST PHARMACEUTICALS LLC            Topic: NCI

    Summary At this timethere is no cure for metastatic breast cancerThe prognosis for these patients is poorWith current standard of care treatmentsthe median survival time is three yearsWe propose to develop a novel bacterial drug delivery therapy into an effective and low toxicity therapeutic for breast cancer metastasesthat targets protein phosphatasePPAberrant phosphorylation in cell signaling is ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Bioactive Surface Engineering for High Yield Manufacturing of Dendritic Cell-Based Cancer Therapeutics

    SBC: FLASKWORKS, LLC            Topic: 100

    PROJECT SUMMARY Dendritic cellsDCare antigen presenting cells that identify and capture foreign bodies and play an essential role in activating both the adaptive and humoral immune responseDCs are an attractive vehicle for therapeutic manipulationparticularly in cancerand are used in antigen pulsed autologous DC therapies and DC stimulated autologous T cell therapiesHoweverdirect isolation of pati ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Technology-Enabled Therapy for Elders with Mild Cognitive Impairment and Co-morbid Insomnia

    SBC: Environment And Health Group, Inc.            Topic: NIA

    Abstract Mild cognitive impairmentMCIis often viewed as a transitional stage between normal aging and early stage of Alzheimer s disease and related dementiaMCI affects up toof the population of older adultsand sleep disturbances have been identified as one of the core neuropsychiatric problems in MCISleep disturbances are associated with a range of negative outcomes for persons with MCIincluding ...

    SBIR Phase I 2018 Department of Health and Human Services

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