You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Treatment of immune mediated diseases that affect the Hispanic community

    SBC: EP PHARMA, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): It has been well established that while the Hispanic population comprises slightly greater than 10% of the US population, they account for a disproportionately higher percentage of disease when compared to non-Hispanicwhites. This includes certain types of cancer, stroke as well as coronary heart disease, diabetes and liver disease. The latter three conditions ...

    SBIR Phase I 2011 Department of Health and Human Services
  2. An Intelligent Capsule Endoscopy Video Analysis Software Platform

    SBC: Xyken, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Gastrointestinal (GI) malignancies are the most common cause of cancer in the world. Of the 10.8 million people in the world each year who develop cancer, approximately 3.3 million have GI malignancies. Until recently,the only sections of the GI tract that could be imaged were the esophagus, stomach and colon through traditional endoscopy. Initial segments of t ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. High Throughput Manufacturing for Three-Dimensional Microfluidic Devices

    SBC: FEMTOFAB, INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Manufacturing based on photolithography has been responsible for ushering in the microelectronics era with enormous societal and economical impact. Extending microfabrication technology to 3D has the potential to revolutionize many diverse fields including biomedicine, energy conversation and storage, and photonic device manufacturing. While many 3D microfabric ...

    SBIR Phase I 2011 Department of Health and Human Services
  4. High Performance, Low Cost PET Scintillators

    SBC: Radiation Monitoring Devices, Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a functional imaging technique with the potential to quantify the rates of biological processes in vivo. The availability of short-lived positron-emitting isotopes of carbon, nitrogen, oxygen and especially fluorine allows virtually any compound of biological interest to be labeled in trace amounts and introduced into the b ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. Compact Hydrogen Peroxide Sensor for Sterilization Cycle Monitoring

    SBC: Physical Sciences Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Improper or incomplete sterilization of manufacturing facilities is a major cause of pharmaceutical product recalls. The economic and societal impact of these recalls is significant and difficult to quantify. Many pharmaceutical companies use vapor phase hydrogen peroxide (VPHP) to decontaminate and sterilize production facilities, including barrier isolators. ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. Mixed-Ligand Targeting of a Nano-Pharmaceutical Against GBM Stem Cells

    SBC: PARABON NANOLABS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): In this Phase I SBIR project, Parabon NanoLabs, Inc. (PNL) will produce a novel, nano- pharmaceutical compound that preferentially selects and destroys brain tumor stem cells (BTSCs) to aid the treatment of glioblastomamultiforme (GBM), one of the most lethal brain cancers. BTSCs in GBM have been identified as a highly tumorigenic cell subpopulation that promot ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. Integrated molecular diagnostic system for the point-of-care

    SBC: BIOHELIX CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): This STTR-AT-NIAID seeks to develop an integrated nucleic acid system based on research done by Catherine Klapperich's laboratory at Boston University. The BU lab-on-a-chip includes a micro solid phase extraction (lt SPE) column, flap valves and hydrophobic vents to gate fluid movements through micro channels, and multiple reaction chambers for experimenta ...

    STTR Phase I 2011 Department of Health and Human Services
  8. Isolation of functional IgGs in the cytoplasm of a novel E. coli expression host

    SBC: NEW ENGLAND BIOLABS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Monoclonal antibodies (mAbs) hold great promise in human health with applications ranging from therapeutic agents that target cancer cells, to diagnostic biomarkers that can detect trace levels of a given antigen. Thispromise is best reflected in global sales of antibodies which reached nearly 31 billion in 2007 and future sales predicted to reach 56 billion ...

    STTR Phase I 2011 Department of Health and Human Services
  9. Covalent Vaccine for HIV

    SBC: COVALENT BIOSCIENCE INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): We propose a Phase I STTR study to develop a novel human immunodeficiency virus (HIV) vaccine strategy with the potential of world-wide efficacy. The HIV/AIDS pandemic remains a major global burden. No test vaccine based on traditional scientific principles has induced sufficiently protective immunity to HIV. Induction of neutralizing antibodies (Abs), the corn ...

    STTR Phase I 2011 Department of Health and Human Services
  10. A NOVEL BIS-INDOLE COMPOUND AGAINST CATHETER COLONIZATION

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Infections associated with medical devices can be serious and even fatal. Catheter colonization and production of a biofilm on the surface of a catheter shortly after implantation are normally the prelude for infections. A number of antimicrobial-treated catheters have been developed to combat these infections, however, many of them have limited clinical effica ...

    STTR Phase I 2011 Department of Health and Human Services
US Flag An Official Website of the United States Government