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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A TELEPHONE-LINKED COMPUTER SYSTEM FOR ELDER CARE

    SBC: New England Research Institutes, Inc.            Topic: N/A

    THE TELEPHONE-LINKED COMPUTER (TLC) SYSTEM HAS BEEN DEVELOPED AND TESTED TO CONVERSE AUTOMATICALLY BY TELEPHONE,USING COMPUTER-GENERATED SPEECH, WITH INDIVIDUALS IN ORDER TO MONITOR THEIR HEALTH STATUS, REPORT THE FINDINGS TO THEIRPROVIDERS OF CARE, AND GIVE THE PATIENTS INFORMATION AND FEEDBACK THAT REINFORCE DESIRABLE SELF-CARE ACTIVITIES. THELONG-TERM OBJECTIVE OF THE PROPOSED PROJECT IS TO DEV ...

    SBIR Phase I 1988 Department of Health and Human Services
  2. OF CELLS SYNCHROTRON X-RAY FLUORESCENCE MICRO-TOMOGRAPHY OF CELLS

    SBC: Radiation Science, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO DEVELOP A RESEARCH RESOURCE FOR STUDYING THE ROLE OF TRACE ELEMENTS IN CELLULARPROCESSES BY LOCALIZING THE ELEMENTS WITHIN THE ORGANELLES OF THE CELL USING MICRON SCALE COMPUTED TOMOGRAPHY (CT) OF SYNCHROTRON INDUCED FLUORESCENT X-RAYS. BECAUSE FLUORESCENCE CT NEEDS ONLY MINIMALLY PREPARED, THICK SAMPLES, THE PROBABILITY OF CONTAMINATION SHOULD BE MUCH LOWER THA ...

    SBIR Phase I 1988 Department of Health and Human Services
  3. HIGH AFFINITY LIGANDS FOR THE COCAINE RECEPTOR

    SBC: Research Biochemicals,            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  4. SYNTHESIS OF FLUORESCENT PROBES FOR MONITORING BRAIN RECEPTOR MOBILITY

    SBC: Research Biochemicals,            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  5. A NOVEL ACCELERATOR FOR RADIOISOTOPE PRODUCTION FOR PET

    SBC: SCIENCE RESEARCH LABORATORY, INC            Topic: N/A

    A NOVEL ACCELERATOR IS PROPOSED TO PROVIDE LOW-ENERGY DEUTERON BEAMS FOR THE PRODUCTION OF SHORT-LIVED RADIO- ISOTOPES FOR POSITRON EMISSION TOMOGRAPHY. THIS ACCELERATORWILL BE CAPABLE OF PRODUCING THE CLINICALLY REQUIRED ACTIVITIES OF 15O IN SOLID TARGETS AND WILL BE SIGNIFICANTLYLESS COSTLY AND EASIER TO OPERATE THAN THE CYCLOTRON ACCELERATOR FACILITIES CURRENTLY IN USE. THIS WILL MAKE POSSIBLE ...

    SBIR Phase II 1988 Department of Health and Human Services
  6. EXTRACORPOREAL REMOVAL OF LDL WITH IMMOBILIZED ENZYMES

    SBC: SEPRACOR, INC.            Topic: N/A

    FAMILIAL HYPERCHOLESTEROLEMIA IS AN INHERITED DISORDER THAT RESULTS IN HIGH SERUM CHOLESTEROL LEVELS ATTRIBUTABLE TO AN ELEVATED LEVEL OF CHOLESTEROL-CARRYING LOW-DENSITY LIPO- PROTEIN (LDL). THIS CONDITION LEADS TO DEPOSITION OF LDL- DERIVED CHOLESTEROL IN SEVERAL TISSUES, ESPECIALLY TENDONS AND ARTERIES, WHICH RESULTS IN A HIGH INCIDENCE OF HEART ATTACK AND, ULTIMATELY, DEATH. EXISTING DRUG AND ...

    SBIR Phase II 1988 Department of Health and Human Services
  7. AFFINITY MEMBRANE DEVICE FOR SELECTIVE CELL SEPARATIONS

    SBC: SEPRACOR, INC.            Topic: N/A

    THE PROPOSED PROGRAM IS DESIGNED TO DEMONSTRATE THE FEASIBILITY OF A SUPERIOR, HIGHLY CONTROLLABLE AND PRODUCTIVE AFFINITY MEMBRANE DEVICE AND PROCESS FOR THE HIGH-RESOLUTION SEPARATION OF PARTICULAR CELL SUBSETS FROM COMPLEX BIOLOGICAL FLUIDS. CELL SEPARATION IS ACCOMPLISHED BY EXPOLITING HIGHLY SPECIFIC INTERACTIONS THAT TAKE PLACE BETWEEN CELL SURFACE RECEPTORS AND THEIR CORRESPONDING IMMUNOAFF ...

    SBIR Phase I 1988 Department of Health and Human Services
  8. MEMBRANE IMMUNOAFFINITY PURIFICATION OF FACTOR VIII:C

    SBC: SEPRACOR, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  9. A NEW LUTEINIZING HORMONE TEST FOR OVULATION DETECTION

    SBC: Standard Scientifics Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  10. MICRO- EXTRACTION DEVELOPMENT FOR DRUG ASSAY

    SBC: SYMBIOTECH, INC.            Topic: N/A

    THE INTERFACE BETWEEN TWO CONTIGUOUS, IMMISCIBLE LIQUID PHASES CAN BE ESTABLISHED WITHIN THE MICROPORES OF A NEW TYPE OF POLYMERIC MEMBRANE. THESE KINDS OF MEMBRANES IN THEFORM OF TINY HOLLOW FIBERS WILL BE INVESTIGATED FOR CONDUCTING LIQUID-LIQUID EXTRACTION AS A FIRST PURIFICATION STAGE IN THE ASSAY OF DRUGS. THE TECHNOLOGY IS APPLICABLE TO VERY SMALL SAMPLES AND SHOULD ALSO FIND USE IN THE ASSA ...

    SBIR Phase I 1988 Department of Health and Human Services

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