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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Prehospital and Emergency Room Stroke Diagnosis Using Quantitative Cerebral Hemodynamics

    SBC: Neural Analytics, Inc.            Topic: NINDS

    Large vessel acute ischemic strokeAISis the leading cause of disability and fourth leading cause of death with approximatelyper year in the United States aloneAlthough treatments including interventionalstentrieverand pharmaceuticaltPAexist for large vessel occlusionLVOthere is not a rapid prehospital tool for diagnoses which guides the use of the correct therapyBecause the time to treatment for s ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Commercialization of HaploSeq as a Service (HaaS) for generating chromosome-span phased genome and exome sequence information

    SBC: Arima Genomics Inc            Topic: 172

    Commercialization of HaploSeq as a ServiceHaaSfor generating chromosome span phased genome and exome sequence information Arima Genomics SPECIFIC AIMSProject Summary Abstract Overof Next Generation SequencingNGSis sequenced via Illumina short read sequencersThis is because of its cost effectiveness and faster turn around timesHowevershort read sequencing technologies lose critical contiguity infor ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Pan-HIV Incidence Assay Development

    SBC: ImmPORT Therapeutics Inc dba Antigen Discovery Inc            Topic: NIAID

    PanHIV Incidence Assay DevelopmentAbstractHIVcontinues to cause the largest number of yearly deaths from a single infectious agent in the world todayDespiteconsiderableadvancesintreatmentofHIVinfectionandAIDSwhichitcausesthereisanurgentneed for better methods of prevention and treatment of HIVinfection and AIDSAs part of this effortthe WorldHealth OrganizationWHOand the Joint United Nations Progra ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. HeartMapp: A Closed-Loop Assessment and Treatment Mobile Application for Heart Failure

    SBC: Posit Science Corporation            Topic: 600

    PROJECT SUMMARY The goal of the current Phase I project is to developto clinical trial readinessand evaluate the feasibility and initial efficacy of a mobile applicationHeartMappdesigned to monitor and treat physical and cognitive symptoms related to heart failureHFin older adultsHeart failureHFis a leading cause of death in the US with costs estimated at $billion per annumfueled by the high rates ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Discovery of Yellow Fever Virus-Specific Epitopes for Development of an Accurate Serodiagnostic Assay

    SBC: ImmPORT Therapeutics Inc dba Antigen Discovery Inc            Topic: NIAID

    DiscoveryofYellowFever VirusSpecificEpitopesforDevelopmentofanAccurateSerodiagnostic AssayAbstractAntibodies to many pathogenic viruses can be detected in bloodserum and or salivaAmong theseare many arbovirusesthat share endemic regions in the western hemisphere and in other parts of theworldThese include the related flaviviruses yellow fever virusYFVdengue virusDENVZika virusZIKVand West Nile vir ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Development of a kit for the targeted depletion of abundant sequencesfromDNA/RNA libraries

    SBC: ARC Bio, LLC            Topic: NIAID

    ABSTRACT Next generation sequencingNGShas the potential to revolutionize how infectious disease is diagnosed and treatedenabling the detection of a wide variety of pathogens in a single testHoweverdespite the increasing adoption of molecular diagnostics in clinical microbiology labsNGS has not become widespread due to its costturnaround timeand the technical and computational expertise required to ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Wearable Vibration Device to Prevent Bone Loss in Postmenopausal Women

    SBC: Theranova LLC            Topic: NIA

    Abstract Osteopenia is a highly common skeletal condition with accelerated loss of bone mass that leads to osteoporosisCharacterized by below normal bone mineral densityBMDosteopenia affectsmillion AmericansIf BMD loss is not mitigatedpatients become osteoporotic and are at increased risk of bone fracturesparticularly of the hip and spineSuch fractures decrease independent livingshorten life and i ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Miniaturized Global Coagulation Assay System in Neonatal and Pediatric Settings

    SBC: Atantares Corp            Topic: NHLBI

    Project SummaryAtantares Corpis seeking funding to develop a standardized foundation of thrombosis evaluationdriven through the principle of unification of standard laboratory and specialized hemostasis testinginclusive of a diversity of tests such as thromboelastographyTEGPT APTTmultiple electrode aggregometer etcwith the potential for iterative advance and multiplexingClinical realization of suc ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Multi-modal AO-LSO Phase Gradient Imaging of the Inner Retina

    SBC: MixZon, Inc.            Topic: NEI

    Project Summary Abstract Physical Sciences IncPSIis continuing the pursuit of new clinical applications and advanced multimodal capabilities for its novel retinal imaging technology based on an adaptive optics line scanning ophthalmoscopeAO LSOThe Compact Adaptive Optics Retinal ImagerCAORIeliminates high speed scanning componentsreduces the clinical footprint compared to research adaptive optics ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. High Density Array Digital PCR for Cancer Rare Mutation Quantification

    SBC: Combinati Incorporated            Topic: 100

    AbstractFor the PhaseSBIR projectCOMBiNATi is looking to prove the feasibility of an injection moldedk array digital PCR consumable for KRAS GR cancer rare mutation quantification analysisDigital PCRdPCRhas drawn attentions in both cancer genomic research and clinical research communities for its ability to detect rare eventshigh sensitivityless prone to inhibitionhigh specificityno need for an in ...

    SBIR Phase I 2018 Department of Health and Human Services

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