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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Evaluating the impact of novel inhibitors of nuclear pore export in SLE

    SBC: KARYOPHARM THERAPEUTICS INC.            Topic: NIAID

    DESCRIPTION provided by applicant Systemic lupus erythematosus SLE is a complex autoimmune disease with a broad spectrum of clinical manifestations affecting several organs and associated with dysregulation of the immune system This disease affects millions of individuals with women and underserved minorities disproportionately burdened It is associated with significant morbidity and morta ...

    SBIR Phase I 2016 Department of Health and Human Services
  2. Rapid Phenotypic Antibiotic Susceptibility Testing

    SBC: BIOSENSE TECHNOLOGIES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Infectious disease has now entered a post antibiotic era where multi drug resistance is increasingly common There is an immediate need for new diagnostics that can determine the susceptibility of pathogenic bacteria to antibiotics rapidly and accelerate the administration of targeted therapy for optimal patient outcomes BioSense Technologies proposes the deve ...

    SBIR Phase I 2016 Department of Health and Human Services
  3. Novel beta lactams as inhibitors of ebola virus infections

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Ebola virus EBOV is a member of the filovirus family that causes severe viral hemorrhagic fever VHF Although infrequent epidemics of EBOV can cause high mortality rates of up to the subsequent medical and social upheaval can be widespread and severe as seen in the recent outbreak in Western Africa which has already caused more than fatalities ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Silk-Based Blood Sample Stabilization for Prostate Cancer Diagnostics

    SBC: VAXESS TECHNOLOGIES INC            Topic: 102

    DESCRIPTION provided by applicant There is a critical need for a blood sample preparation and processing method that can preserve integrity and improve downstream analysis while being completely free of cold storage requirements Such a technology would allow clinicians and patients to collect blood samples for cancer screening monitoring and or diagnosis comfortably from patientandapos s hom ...

    SBIR Phase I 2016 Department of Health and Human Services
  5. Multimodal optical imager for inner ear hearing loss diagnosis

    SBC: Physical Sciences Inc.            Topic: NIDCD

    DESCRIPTION provided by applicant Sensorineural hearing loss SNHL which typically originates in the inner ear is the most common otologic problems caused by aging and noise trauma The cochlea a delicate and complex biological mechanosensory transducer has been extensively studied with the goal of improving diagnosis of SNHL and developing therapeutic approaches for it Today clinical i ...

    SBIR Phase I 2016 Department of Health and Human Services
  6. Selective HDAC3 Inhibitors as a Novel Therapy for Drug Addiction

    SBC: KDAc Therapeutics, Inc.            Topic: R43

    DESCRIPTION provided by applicant Drug addiction is a serious and growing public health problem in the US Combining medications with cognitive behavioral therapy CBT is an effective way for patients to attain and sustain abstinence yet current safe medications are limited and there are no FDA approved therapeutics for cocaine addiction where CBT alone has poor success and relapse rates a ...

    SBIR Phase I 2016 Department of Health and Human Services
  7. Biopsy Probes with Real time Multi modality Image Guidance for Peripheral Lung Nodules

    SBC: LX Medical            Topic: NCI

    DESCRIPTION provided by applicant Recent technological advances have enabled low dose spiral CT to become an effective tool for lung cancer screening The majority of pulmonary nodules detected on CT however are small and difficult to diagnose While CT guided transthoracic needle biopsy CT TTNB has high diagnostic accuracy to depending on nodule size the risk of complications su ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Smartphone Simulator for Realistic Radiation HAZMAT and Emergency Response Training

    SBC: CAPESYM, INC            Topic: NIEHS

    DESCRIPTION provided by applicant Smartphone Simulator for Realistic Radiation HAZMAT and Emergency Response Training Project Summary High levels of radioactive radiation is a major source of public health This proposal seeks to develop a simulator based tool for radiation HAZMAT and emergency response training The smartphone simulator produces a virtual environment where the trainee can expl ...

    SBIR Phase I 2016 Department of Health and Human Services
  9. High throughput multiplexed assay for chemicals affecting neuron differentiation

    SBC: JuvoBio Pharmaceuticals Inc.            Topic: 113

    DESCRIPTION provided by applicant High throughput multiplexed assay for chemicals affecting neuron differentiation Neurodevelopmental disorders NDDs affect to of the million children born in the US each year The incidence rates for NDDs have been rising Exposures to toxic chemicals may have contributed to NDDs Due to neuronal development and maturation processes fetus n ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. Sensor Image-Based Environmental Listening Assistant

    SBC: SPEECH TECHNOLOGY/APPLIED RESEARCH CORP.            Topic: Y

    DESCRIPTION provided by applicant Environmental Listening Assistance from Sensor Images Recent years have witnessed a veritable explosion of innovative personal audio devices wireless sound systems active earpieces and other personal digital audio devices These appliances are typically much less expensive and seemingly much more innovative than traditional hearing aids But hearing aids ...

    SBIR Phase I 2016 Department of Health and Human Services

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