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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Enhanced Imaging for Visual Prostheses

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: NEI

    Project Summary/Abstract The proposed project relates to the commercialization of a promising new thermal/visual imaging system to be used as an input modality to visual prostheses and other low vision aids. Visual prostheses, including Second Sight's Argus® II retinal prosthesis, which restores partial vision to people blinded by diseases such as retinitis pigmentosa and macular degeneration, an ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Wiring Catheter for Crossing Complex Chronic Total Occlusions

    SBC: Minnesota HealthSolutions Corporation            Topic: NHLBI

    Project Summary/Abstract We propose to develop an innovative wiring catheter system to reliably direct subintimal crossing and re-entry into the artery true lumen during treatment of complex arterial chronic total occlusions (CTO). The proposed system will improve techniques for treating complex CTOs during percutaneous coronary and peripheral artery interventions (PCI). Atherosclerosis drives dev ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Novel contrast agent tool for musculoskeletal injection procedures

    SBC: AGITATED SOLUTIONS INC.            Topic: NIAMS

    Abstract Injection therapy for intra and extra-articular structures using ultrasound guidance is one of the principal medical treatments available for musculoskeletal (MSK) pain, however, these injections are inaccessible to patients who are obese or unable to wait a long time to visit a specialty center. Correct needle placement and visualization of the injectate is important to enable orthopedis ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. High-throughput discovery platform for modulators of cardiac muscle proteins to treat heart failure

    SBC: Photonic Pharma LLC            Topic: NHLBI

    Project Summary This Phase I SBIR collaboration between Photonic Pharma LLC (PP) and the University of Arizona (UA) will establish proof-of-concept for an innovative drug-discovery campaign for treatment of heart failure (HF), targeting cardiac myosin-binding protein C (MyBP-C). There is an urgent need for novel therapies for HF, a major health problem affecting 1 in 30 adults in the US. MyBP-C ha ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Promoting adult hippocampal neurogenesis using antisense oligonucleotides as an Alzheimer's disease therapy

    SBC: BOLDEN THERAPEUTICS, INC.            Topic: NIA

    PROJECT SUMMARY There is an enormous need for therapeutics to prevent and treat Alzheimer's disease (AD). Adult Hippocampal Neurogenesis (AHN) is critical for normal learning and memory, but it declines in patients with AD. Work in animal models has underscored the role of AHN in improving cognition in the face of AD pathology. Thus, restoring AHN has emerged as an attractive target for an AD ther ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. A CT-Based Multiparametric Imaging Biomarker for Assessment of Pediatric Interstitial Lung Disease

    SBC: Imbio, LLC            Topic: NHLBI

    PROJECT SUMMARY Childhood (diffuse) interstitial lung diseases affects infants, children, and teens and manifests as dyspnea, hypoxemia, and respiratory compromise resulting in high morbidity and mortality or life-long sequelae for survivors. Despite improvements in the understanding of and interventions for pediatric diffuse lung disease in the past 15 years, the current standard-of-care for conf ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Entrepreneurial development award for a novel Alzheimer's disease therapeutic

    SBC: BOLDEN THERAPEUTICS, INC.            Topic: Y

    The aging population in the US and globally has led to an urgent need for therapeutics to prevent and treat Alzheimer's disease (AD). Adult Hippocampal Neurogenesis (AHN) is critical for normal learning and memory and declines in patients with AD. Work in animal models has underscored the role of AHN in improving cognition in the face of AD pathology. Thus, restoring AHN has emerged as an attracti ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Automated System for Accurate Determination of Activities of Daily Living for Independently-Living Persons with Alzheimers Disease and Related Dementias

    SBC: ASTER LABS, INC.            Topic: NIA

    Project Abstract In this Phase I SBIR project, ASTER Labs will develop and evaluate an innovative system to automatically and accurately detect Activities of Daily Living (ADL) performed by persons with Alzheimer’s disease and related dementias. It will address a current need to equip caregivers and health care providers, including physicians and cognitive rehabilitation therapists, with reliabl ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Joyuus: A Web-based Tool for Postpartum Care Self-care to Address the Complex Needs of Underserved Women

    SBC: JOYUUS, LLC            Topic: 100

    PROJECT SUMMARY/ABSTRACT In the United States, the postpartum period is a critical time for both maternal and child health; the US maternal mortality rate is the highest among other developed, high-income countries. More than half of all maternal deaths occur postpartum, from one day to one year after birth.1-9 There are vast racial and ethnic disparities in maternal mortality and severe morbidity ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Use of a novel physiologic measure for the assessment and monitoring of vincristine induced peripheral neuropathy (VIPN) in children and adolescents.

    SBC: ALGOMETRX INC            Topic: 102

    In this application, we propose the examination of a novel physiologic measure of vincristine-induced peripheral neuropathy (VIPN) in pediatric patients. Establishment of such a measure will enable the objective characterization of both the positive and negative symptoms of neuropathy in pediatric patients treated with vincristine in order to enable early detection and management of the resulting ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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