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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Laser Speckle Imaging Chip for Telehealth Applications

    SBC: Vasoptic Medical, Inc.            Topic: NIA

    DESCRIPTION provided by applicant There is a strong unmet need for a low cost and convenient technology that can assist researchers and healthcare personnel in gathering vascular data Such vascular imaging technology could assist in the short term clinica research on the diagnostics disease progression and effect of treatment prevention strategies ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A Patient-Driven Rehabilitation System to Improve Upper Limb Amputee Outcomes

    SBC: Infinite Biomedical Technologies, LLC            Topic: NICHD

    DESCRIPTION provided by applicant A patient driven rehabilitation system to improve upper limb amputee outcomes The goal of our research program is to develop technological solutions that restore function for upper extremity amputees For these individuals one of the most promising developments in the past decade has been the introduction of fully dexterous terminal devices However an effe ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Development and testing of a behavioral activation mobile therapy for elevated depressive symptoms

    SBC: MOUNTAINPASS TECHNOLOGY LLC            Topic: 104

    DESCRIPTION provided by applicant Approximately of the population experiences elevated depressive symptoms Kubik et al Despite recent research suggesting that overall population mortality would be reduced by if the effects of subthreshold depression could be blocked completely the majority of individuals with elevated depressive symptoms never receive evidence based treat ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. iRFP-Max: A novel infrared fluorescent protein for deep tissue imaging

    SBC: Revolve Biotechnologies, Inc.            Topic: 101

    DESCRIPTION provided by applicant Fluorescent proteins FPs are important life science research tools with a market size in excess of $ million FPs are used in many applications such as in vivo tissue imaging cell tracing and intracellular protein tracking However current tools mostly based on GFP family templates e g Monster Green r from Promega tdTomato from Clontech suffer sev ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. TB Diagnostics at the Point of Care

    SBC: AKONNI BIOSYSTEMS INC.            Topic: NIBIB

    DESCRIPTION provided by applicant Of all diseases tuberculosis TB represents one of if not the greatest health disparity between whites and minorities For every TB infected white person in the United States there are an estimated African Americans Latinos Native Americans Asians and Native Hawaiian Pacific Islanders with this disease Compounded with this dispari ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Long-term anti-angiogenic activity of intravitreal ellipsoid particles for NVAMD

    SBC: Asclepix Therapeutics, Inc.            Topic: N

    DESCRIPTION provided by applicant Long term anti angiogenic activity of intravitreal ellipsoid particles for NVAMD Niranjan B Pandey Ph D PI Aleksander S Popel Ph D Co I Jordan J Green Ph D Co I Peter A Campochiaro M D Co I of subaward Project Summary Current therapies for wet age related macular degeneration AMD target vascular endothelial growth factors VEGFA and pla ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Novel microarrays for DNA genotyping in the presence of excess background DNA

    SBC: SCANOGEN INC.            Topic: 172

    DESCRIPTION provided by applicant DNA microarrays are a primary tool for DNA genotyping because of their capacity to detect multiple targets simultaneously However DNA microarrays require fluorescent labeling and long incubation steps which limit their applicability Furthermore DNA microarrays are not capable of detecting DNA targets in the presence of excess background DNA This capacity ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Novel High Affinity VEGF Analogs For Targeted Imaging of Thyroid Cancer

    SBC: TROPHOGEN INC            Topic: 102

    DESCRIPTION provided by applicant Thyroid cancer of follicular origin is the most common malignancy of endocrine tissues disproportionally affecting women and is one of the few cancers greatly increasing in incidence andamp prevalence for unknown reasons not solely attributable to improved diagnosis Most patients require lifelong diagnostic surveillance with radioiodine imaging to detect re ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health

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