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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
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SBC: Allinaire Therapeutics, LLC Topic: NHLBI
Summary Abstract The ultimate goal of this project is the validation of a humanized endothelial monocyteactivating protein IIEMAP IIneutralizing monoclonal antibodymAbfor progression to clinical evaluation as a novel treatment for patients with influenza associated lung injuryInfection with influenza virusIAVremains a major world wide health threat to high risk populations including the young and ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
3D Holographic Guidance, Navigation, and Control (3D GN&C) for Endovascular Aortic Repair (EVAR)SBC: CENTERLINE BIOMEDICAL INC Topic: NHLBI
Project Summary This project will develop newD visualization to improve stent graft deployment during minimally invasive endovascular aortic repairEVARby overcoming limitations ofD x ray fluoroscopyfluoroD holographic guidancenavigation and controlD GNandamp Cwill be provided to decrease fluoro radiation dose burden to patients and OR staff during treatment of aortic aneurysmsparticularly when dep ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: Universal Adherence LLC Topic: N
Project Summary Abstract Universal Adherence is an emerging medical device company dedicated to improving adherence to ocular medications through innovative technical solutionsOur proposed Devers Drop DeviceDwill accurately track when a patient removes an eye drop bottle capcommunicate usage data wirelessly to a database that researchers can accessand send alerts to patients when a medication is d ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: COLUMBUS NANOWORKS, INC. Topic: 400
Fluorescent nanodiamonds are biocompatibleinfinitely photostableand fluoresce in a variety of wavelengthsincluding the near infraredNIRregionThese characteristics suggest transformative applications in areas ranging from pure biological research to biomedical imagingwhere protein conjugated nanodiamonds could be targeted to specific tissues in living patients or even structures within individual c ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: SOAR TECHNOLOGY INC Topic: DHA17C001
In this proposal we support the development of a hypoxia test battery by designing and developing a domain general tool suite for processing, synchronizing, and evaluating data from cognitive, behavioral, and physiological measures.The proposed Griffon Tool Suite addresses many of the practical requirements demanded by a flexible test battery. The effort falls into three major thrusts.First, we pr ...STTR Phase I 2018 Department of DefenseDefense Health Agency
SBC: Sunomix Therapeutics Topic: NIAID
ABSTRACTA staggering number of overbillion individuals worldwide are currently infected with herpes simplex virus typeand or typeHSVandampHSVwhich cause genital herpesMost HSV seropositive individuals are asymptomaticASYMPand never have any recurrent herpetic diseaseIn contrasta small proportion is symptomaticSYMPwith frequentoften lifelong bouts of recurrent herpetic diseasea result of reactivati ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: Z-Quick, LLC Topic: NIAID
Project Summary Abstract Miami has emerged as the US epicenter of the now global Zika virusZIKVepidemicThe consequences of infection remain to be fully elucidatedbut the probable link between ZIKV infection and fetal developmental complications raises enormous concern as to the potential impact of ZIKVCurrent emergency use authorizationEUAcommercial assays detect ZIKV RNAthe presence of ZIKV speci ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: Truvitech, LLC Topic: NCATS
PROJECT SUMMARY Drugs act by altering the activities of particular componentstargetswithin a cell or organismThusdrug discovery campaigns begin by identifying a targetfollowed by screening this target with compounds to identify leads that can be developed into a drugUnfortunatelyidentifying effective drug targets for a given diseaselet alone for individual patientse gin highly heterogeneous cancer ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: Marblehead Medical LLC Topic: 106
PROJECT SUMMARY ABSTRACTThis research program s broadlong term objective is to improve health outcomes for patients suffering fromacute ischemic strokeAISresulting from large vessel occlusionsWe will achieve this purpose by developingimproved access tools for stroke intervention procedureswhich specifically target tool innovations that providesupport for embolectomy devices and arrest flow during ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: DFUSION INC. Topic: NICHD
Althoughyear olds are onlyof the U Ssexually active populationthey account for nearlyof themillion new cases of sexually transmitted infectionsSTIeach yearAlthough historically lowthe U Steen pregnancy rate continues to be one of the highest in the developed worldEvidence based prevention efforts can help avoid the costs and health consequences associated with STIs and unwanted teen pregnancy amon ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health