Award Data

AbstractThe alarming scope of the rapidly growing opioid epidemic has commanded the nation’s attention. The White House’s Council of Economic Advisers estimates that in 2015, the economic cost of the opioid crisis was over $504.0 billion (2.8% of GDP); and it is only expected to continue rising. Today, 1 in 5 fatalities amongst young adults is opioid related; with half a million fatal overdose ...

Deep Neural Networks have become ubiquitous in the modern analysis of voluminous datasets with geometric symmetries. In the field of Particle Physics, experiments such as DUNE require the detection of particle signatures interacting within the detector, with analyses of over a billion 3D event images per channel each year; with typical setups containing over 150,000 different channels.  In an ...

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

Software and hardware flaws can be exploited to make programs perform unintended computations or leak sensitive data. We propose to counter these threats by isolating libraries and other program units inside a single process. The developer will insert source-level annotations that i) map code and data units to compartments and ii) capture how each compartment is intended to interact with others, i ...

Nanohmics, teaming with CUNY, proposes to develop high-performance, metamaterial-based lenses that can be scaled up to tens of centimeters of clear aperture for ISR and other imaging applications. These high-throughput achromatic metalenses will operate across all visible wavelengths, 400-700 nm, demonstrating polarization-independent, low-aberration f/2 imaging comparable to much bulkier conventi ...

The Ballistic Missile Defense System (BMDS) is aptly described as a system of systems. Each subsystem within the BMDS is comprised of many custom-designed firmware and software elements. The designs can only be integrated together upon receipt of physical hardware (Circuit Card Assemblies). This delay introduces significant risk to the developer and procurer since system-level design issues may no ...

The proposed work will develop a massively parallelized architecture for Monte Carlo simulation of real-time fire control schedulers. The parallelized architecture will utilize the recent developments in multiprocessing/multithreading technology based on graphical processing units. The system will be designed to perform in real-time assuming non-collocated sensors observing the threats and then co ...

Despite the tremendous benefits of additive manufacturing (AM) to our warfighters, uncertainty in fatigue life predictions have been a major roadblock for certifying metallic AM parts to fly. We are proposing a hybrid modeling/inspection approach to estimate fatigue life of AMed parts using damage tolerance analysis combined with inspections. The new developed tool is expected to provide certifica ...

An additive-manufacturing process will be developed for printing high-quality freeform inorganic gradient-index (GRIN) optical elements. Candidate nanocrystal materials including ZnS, ZrO, TiO2, PbSe, and rare-earth-doped metal oxides, will be synthesized and characterized. A process for inkjet-print depositing high-volume-percent loading density of binary, ternary, quaternary, etc., nanoparticle ...