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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advance Early Detection of Lupus Nephritis with ClearGold

    SBC: CLEARNANO INC            Topic: 400

    SummarySystemic lupus erythematosusSLEor lupus is an autoimmune disease that impacts more thanmillion people worldwideincludingmillion AmericansNearlyof these patients will develop lupus nephritiswhich can cause kidney failureAs a resultits financial burden to individual patient can reach $yearmuch higher than many other diseases because of kidney transplantationAlthough early treatment of lupus n ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Advancing clemizole for hepatitis C: towards a pre-IND package

    SBC: EIGER GROUP INTERNATIONAL, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Over 150 million people worldwide are infected with the hepatitis C virus (HCV), which is an important cause of chronic liver disease. Current therapies are inadequate. Our long-term objective is to bring a new class of anti-HCV drugs to the clinic. We recently discovered and genetically validated a new target within the HCV non-structural protein NS4B, consist ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Advancing Optical Imaging and Classification to Enhance Biodiversity Monitoring

    SBC: OCEANSPACE LLC            Topic: 07a

    Foundational to assessing biodiversity is an effective and cost-efficient method to identify and quantify the components of biodiversity. While a substantial proportion of present and proposed biofuel production systems are terrestrially based, the environmental impacts wash down the watershed into the aquatic ecosystem. Biodiversity monitoring can therefore be efficiently focused on surface water ...

    STTR Phase I 2020 Department of Energy
  4. A Fast-Response, Electronically Controlled Fuel Injection System for Small Heavy Fuel Engines with Multi-Fuel Capabilities

    SBC: MAINSTREAM ENGINEERING CORP            Topic: N10AT033

    Advances in electronically controlled injection technologies for diesel engines have provided a method to improve medium- to heavy-duty engine performance through increased injection pressures, multiple injections, and injection rate shaping. Although these injection systems have been primarily limited to larger engines, the ability to rapidly and precisely meter fuel for smaller engines is partic ...

    STTR Phase I 2010 Department of DefenseNavy
  5. A Fiber-Optic-Based External Pipe Sound Pressure Level Sensing System

    SBC: INTELLIGENT FIBER OPTIC SYSTEMS CORP            Topic: N10AT016

    Intelligent Fiber Optic Systems Corporation (IFOS) and Georgia Tech propose a fiber Bragg grating (FBG) integrated sensor system capable of measuring the pipe wall "breathing mode" in order to infer the fluid-borne sound pressure level (SPL) in a pipe. The proposed new measurement technique makes it possible to externally measure the fluid-borne sound level in a noisy piping system. The state-of-a ...

    STTR Phase I 2010 Department of DefenseNavy
  6. A Genes-to-Molecules Platform for Expanding Natural Product Diversity

    SBC: Lassogen, Inc.            Topic: NCCIH

    Project Summary Natural products (NPs) and derivatives thereof provide a rich source of chemical matter for drug discovery and development. Over the past 30 years, NP-derived drugs have accounted for more than 35% of FDA approvals. Despite their demonstrated importance, development of new NPs has slowed over the past 15 years due to the lack of efficient methods for discovery, production, and opti ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. AgileBeam Reconfigurable Free Space Optical Communication System

    SBC: SA PHOTONICS, LLC            Topic: AF18AT010

    Free Space Optical (FSO) communication systems provide many benefits for satellite communications, including high data rates and low Size, Weight and Power (SWaP) compared to traditional RF communication systems. Additionally, FSO systems operate without RF emissions and are inherently immune to RF interference and jamming. The narrow optical beams and small Field-of-View of the optical receivers ...

    STTR Phase II 2020 Department of DefenseAir Force
  8. A Hierarchical and Extendable, Component-Based Simulation Tool for Aircraft Thermal Management Systems

    SBC: CFD RESEARCH CORPORATION            Topic: N19BT025

    The requirements for thermal management on tactical aircraft systems have reached a level at which integrated system design must be considered early in the aircraft design process. An integrated propulsion, power and thermal modeling and simulation design approach is necessary for reduced size, weight and power requirements. At the same time, there is an urgent need for capabilities that enable an ...

    STTR Phase I 2019 Department of DefenseNavy
  9. 26(a): High Duty Cycle Inverse Free Electron Laser

    SBC: RADIABEAM TECHNOLOGIES, LLC            Topic: 26a

    Laser based advanced accelerators can achieve very high accelerating gradients, but their duty cycle is limited by the laser power availability and media recovery time. Inverse Free Electron Laser (IFEL) is a vacuum farfield laser accelerator scheme which does not rely on a medium (plasma) or a structure (metal or electric) and therefore is potentially capable of accelerating charged particles ver ...

    STTR Phase II 2016 Department of Energy
  10. A high-efficiency, low-cost, single-use purification technology for therapeutic antibody manufacturing

    SBC: Bondwell Technologies Inc.            Topic: 400

    Therapeutic antibodies have had a profound impact on treatment of many types of cancer and autoimmune diseasesAs a resultfive of the top ten best selling drugs ofwere therapeutic antibodiesMore than seventy therapeutic antibodies have been approvedand over six hundred antibody based products are in clinical developmentHoweverantibodies are extremely expensive to produceand large amounts of antibod ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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