Award Data

To address the DHP need for a controlled, target-specific delivery system for topical treatment of peripheral neuropathy (PN), Physical Optics Corporation (POC) proposes to develop Nano Therapeutics for Peripheral Neuropathy (NATPEN). The NATPEN will include a nanocarrier (NC) loaded with specific drugs, a biocompatible gel to contain the NC, and a microneedle patch for transdermal delivery of the ...

The overall incidence of burns in current military operations has nearly doubled during the past few years and this type of injury remains a common component of armed conflicts. To address the need for prevention of scar contracture following burns, Physical Optics Corporation (POC) proposes to develop a new Control of Scar Contracture After Burn injury (SCAB) topical formulation. The SCAB is desi ...

To address the DHP need for a biometric model to address dismounted complex blast injury of the pelvis, abdomen, and genitals, Physical Optics Corporation (POC) proposes to develop a new Pelvic Model with multi-Sensory Data Acquisition (ELVIS). This proposed model is based on the combined development of a numerical model for blast effect prediction for different impact forces and an anatomically c ...

To address the Army Medical Research and Material Command"s need for closed-loop anesthesia system Physical Optics Corporation (POC) proposes to develop a new Intelligent Sensor for Closed Loop Anesthesia Delivery (iSCAD) system based on a novel optical spectroscopy technique and a multisensor fusionbased control algorithm. The key innovation in the iSCAD is its novel system design that allows acc ...

Thermal injury is common in military conflicts due to primarily to the widespread use of explosive devices. Burns can produce scars that are excessive, physically debilitating and functionally damaging. There is a critical need for an effective product that can control bacterial contamination and prevent colonization, mitigate inflammation, and diffuse to or reach necrotic and damaged tissue resul ...

We propose to identify biomarkers associated with pain and design a biomarker assay that can be used by scientists to study pain in many different diseases/conditions. Two biomarker discovery strategies will be used to identify candidate biomarkers in diseases associated with chronic pain. Diseases include fibromyalgia, rheumatoid arthritis and osteoarthritis. From a literature search, we have ...

Miniaturized smart munitions are seeing increasing use across all branches of the Department of Defense (DoD) in order to meet the ever evolving mission needs for the U.S. warfighter. These smart micromuntions have been enabled by advances in capabilities and miniaturization of critical microelectonic and microelectromechanical systems such as sensor, navigational, communications, and triggering ...

Small multirotor Unmanned Aerial Vehicles (UAVs) are well suited for sensing and situational awareness missions in closed, confined, and constrained (C3) environments. However, autonomous navigation of small VTOL UAVs is very challenging in C3 environments. Current state of the art navigation methods uses vision and LIDAR to build a map, localize, and plan paths. These methods tend to be computati ...

Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

Servicemembers exposed to blasts have frequent complaints of vertigo, gaze instability, balance problems, motion intolerance, and other symptoms consistent with peripheral vestibular pathology. Current vestibular rehabilitation is an exercise-based approa