You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Novel agonists and antogonists of chemokine receptors

    SBC: ICOGENEX CORPORATION            Topic: N/A

    DESCRIPTION (provided by the applicant): A key event in the initiation and maintenance of an inflammatory response is the recruitment of immune effector cells to the site of a local immune response. This recruitment and retention is mediated by chemoattractant compounds, of which chemokines are an essential component. The chemokine family consists of ~50 small proteins, which mediate effects thro ...

    SBIR Phase II 2003 Department of Health and Human Services
  2. Effector of APP to Lower Amount of beta-Amyloid Protein

    SBC: ICOGENEX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer's disease is a devastating common disorder affecting primarily elderly people with a prevalence of five percent of the population over sixty-five, increasing to twenty percent over the age of eighty. An estimated ten million people in the world have the disease, at a cost of $65 billion for U.S. patients in 1995. The prevalence and the cost continue t ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. A Serological Marker for Hepatocellular Carcinoma

    SBC: ILLUMIGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Expression of the gene encoding phospholipase A2 group 13 (PLA2G13) was found to be significantly upregulated in hepatocellular carcinoma (HCC) tissue relative to adjacent nonmalignant liver. In a search of public gene expression databases, only one cDNA library was found to contain the sequence encoding PLA2G13 suggesting that the gene is rarely expressed or e ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Novel Hepatitis C Drugs

    SBC: ILLUMIGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Illumigen is pursuing an alternative genetics-driven approach to drug discovery that relies on the identification of mutations associated with health rather than disease. Beneficial or health-inducing mutations, like most disease-causing mutations, are expected to negatively impact gene function in a way that can be mimicked by an inhibitory drug. This Phase I ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. Proteomics software package for the detection of cancer

    SBC: INCOGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR project proposes the development of a software package containing bio-computational tools to facilitate accurate diagnosis of cancer based on classification of proteomics data obtained through mass spectrometry (MS). The software will accept MS data produced from a wide range of instruments but is specifically targeted toward MALDI/SELDI TOF analysis ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Rapid Test for Monitoring Dust Mite Avoidance in Homes

    SBC: Indoor Biotechnologies Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Allergens found in the home derived from dust mites, animal dander, cockroaches and fungi are commonly associated with the development of asthma. Reducing allergen exposure is a primary goal of asthma management, yet there are no simple tests that enable allergic patients and consumers to measure allergen exposure in the home. In Phase I, the feasibility of usi ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Rapid Test for Monitoring Dust Mite Avoidance in Homes

    SBC: Indoor Biotechnologies Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Allergens found in the home derived from dust mites, animal dander, cockroaches and fungi are commonly associated with the development of asthma. Reducing allergen exposure is a primary goal of asthma management, yet there are no simple tests that enable allergic patients and consumers to measure allergen exposure in the home. In Phase I, the feasibility of usi ...

    SBIR Phase II 2003 Department of Health and Human Services
  8. Vaginal Gel to Enhance Lubrication & Sperm Function

    SBC: ING FERTILITY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): ING Fertility, LLC ("ING") is a woman-owned company that markets and brands products targeted to the demographic sector of couples trying to conceive children. This Phase I SBIR proposal aims to validate proof of concept for a vaginal gel, "Pro~Cept, designed to provide sperm-safe personal lubrication and an optimal environment for post-ejaculatory sperm funct ...

    SBIR Phase I 2003 Department of Health and Human Services
  9. Fractal Modeling of Biomedical Time Series in S-Plus

    SBC: INSIGHTFUL CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to provide a comprehensive state-of-the-art software package, S+FRACTAL, for modeling and data analysis of fractal processes. The overall implementation will be in the S-PLUS object oriented language. The specific aim of the software is to provide comprehensive and effective tools for estimating deterministic or stochastic frac ...

    SBIR Phase II 2003 Department of Health and Human Services
  10. Efficient Statistical Algorithms for Dropout Data

    SBC: INSIGHTFUL CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): This research will develop a statistical software library in S-PLUS for dropout data. Missing and dropout data are common nature in longitudinal studies. When the dropout process is related to the outcome process, it creates tremendous challenges in analyzing such data. No commercial software currently considers the dropout mechanisms in dealing with informati ...

    SBIR Phase II 2003 Department of Health and Human Services
US Flag An Official Website of the United States Government