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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Digital Video Monitor and Analysis of Seizures with EEG

    SBC: Clever Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The behavioral components of electrographic seizures in rodents, primarily rats and mice, are generally used as the most fundamental basis for the presence of epileptic seizures. Numerous research grants use analysis of animal seizures as a fundamental component of the research, even research aimed at molecular and cellular mechanisms. The abnormal behaviors d ...

    SBIR Phase I 2003 Department of Health and Human Services
  2. High throughout phenotypic screen: drug effects on home

    SBC: Clever Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a completely functioning prototype system for rapid and automated high-throughput phenotypic screening: drug effects on home-cage behavior in mice or rats. The purposes of the project are to develop technologies and tools that can automatically measure different behaviors in mice to reliably predict drug-induced changes in home-cage and lo ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. High throughout phenotypic screen: drug effects on home

    SBC: Clever Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a completely functioning prototype system for rapid and automated high-throughput phenotypic screening: drug effects on home-cage behavior in mice or rats. The purposes of the project are to develop technologies and tools that can automatically measure different behaviors in mice to reliably predict drug-induced changes in home-cage and lo ...

    SBIR Phase II 2003 Department of Health and Human Services
  4. Rare Event Imaging

    SBC: Sciperio, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Rare-event imaging has profound implications for the early identification of potentially correctable terminal diseases, especially for cancer. What is required is a highly accurate "routine" test to be given to all patients, not just to those deemed at risk. This requires not only a highly accurate and repeatable process, but also a reasonably fast and inexp ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. A Genetic System For Kinetoplastid Drug Discovery

    SBC: COMPLEGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to apply a novel, well developed cost effective means of drug target and drug discovery to parasitic disease, focusing on Trypanosoma cruzi and Leishmania, the causative agents of Chagas disease and Leishmanaisis respectively. This project will generate comparative compound screens to identify new anti-kinetoplastid compounds that ar ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. PRE-CLINICAL DEVELOPMENT OF NOVEL HSV-2 ANTIGENS

    SBC: CORIXA CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of our proposed Phase II studies is to develop a vaccine for HSV-2 capable of eliciting human CD8+ and Th1-type CD4+ T cell responses for evaluation in humans. Prior clinical experience suggests that elicitation of immune responses other than neutralizing antibody in humans will be important to achieve a positive clinical effect. HSV-2 antigens ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. PRE-CLINICAL DEVELOPMENT OF NOVEL HSV-2 ANTIGENS

    SBC: CORIXA CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of our proposed Phase II studies is to develop a vaccine for HSV-2 capable of eliciting human CD8+ and Th1-type CD4+ T cell responses for evaluation in humans. Prior clinical experience suggests that elicitation of immune responses other than neutralizing antibody in humans will be important to achieve a positive clinical effect. HSV-2 antigens ...

    SBIR Phase II 2003 Department of Health and Human Services
  8. Public Use Microdata Custom Analytical Reports

    SBC: DECISION DEMOGRAPHICS            Topic: N/A

    DESCRIPTION (provided by applicant): Decision Demographics has designed an affordable demographic analysis system, Custom Analytical Reports. These standardized, inexpensive, and easy-to-produce reports use Public Use Micro data Sample (PUMS) data from the decennial census. While creating such reports has long been possible, the process requires sophisticated expertise and high cost. This project ...

    SBIR Phase I 2003 Department of Health and Human Services
  9. Public Use Microdata Custom Analytical Reports

    SBC: DECISION DEMOGRAPHICS            Topic: N/A

    DESCRIPTION (provided by applicant): Decision Demographics has designed an affordable demographic analysis system, Custom Analytical Reports. These standardized, inexpensive, and easy-to-produce reports use Public Use Micro data Sample (PUMS) data from the decennial census. While creating such reports has long been possible, the process requires sophisticated expertise and high cost. This project ...

    SBIR Phase II 2003 Department of Health and Human Services
  10. Knowledge Empowerment for Youth with Solid Tumors

    SBC: DEGGE GROUP, LTD.            Topic: N/A

    DESCRIPTION (provided by investigator): Childhood cancer is the number one disease killer of children and adolescents in North America. For adolescents, a diagnosis of cancer comes at a particularly vulnerable developmental stage in their lives. Phase I focus group interviews indicated that these adolescents are adamant about wanting to know and learn about all aspects of their disease and how i ...

    SBIR Phase I 2003 Department of Health and Human Services

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