Award Data

Filoviruses, consisting of two major virus families including the ebolaviruses and marburgviruses (MARV and RAVV), cause periodic outbreaks of severe viral hemorrhagic fever with mortality rates as high as 90%. Since it is difficult to predict the species that would dominate future outbreaks, development of broadly protective therapeutics to prevent and manage future filovirus outbreaks is of high ...

Successful completion of this Phase II proposal will fully characterize and evaluate a material for use in RF windows on hypersonic flight vehicles. Phase II will specifically examine the materials suitability through RF testing in X, Ku, and Ka bands and at elevated temperatures to 2000°F. The desired outcome will be a material with predictable, repeatable dielectric properties over frequency ...

Project Summary Bacillus anthracis (Ba) is a Gram-positive spore forming bacterium that is listed as an agent of highest concern (Category A) by NIAID and CDC. Ba is easy to grow, and its spores can be formulated into highly stable powder form and disseminated as aerosol or used to contaminate food or water. In 2001, letters laced with powdered anthrax spores were mailed to several US politicians. ...

In Phase I, ISSI will design and demonstrate a laser absorption-based sensor for time-resolved measurements of combustion fuel/product concentrations (H2O, CO, CO2 and fuel) and gas temperature within the detonation channels and nozzle exit-plane of a rotating detonation rocket engine (RDRE). The goal of this STTR is to develop a single sided sensor that plugs into the outer wall of the RDRE simil ...

FIRST RF will lead the Phase II effort and will leverage the system architecture of the MAINLINE system and integrate multifunctional SiGe integrated circuits (ICs) developed by The University of California San Diego under the supervision of Prof. Gabriel Rebeiz. The SiGe devices developed during the Phase II effort will significantly reduce the power requirements of the MAINLINE system allowing f ...

The broader impact of this Small Business Technology Transfer (STTR) Phase I project will provide a low-cost wearable Internet-of-Things (IoT) device for upper extremity physical therapy rehabilitation. The project will contribute to the ultimate goal of helping patients suffering from stroke or joint-related injuries of the upper extremities. The project will result in a body of knowledge that ph ...

This SBIR Phase I project aims to focus on the challenges neuroradiologists and neurosurgeons experience when visualizing complex brain aneurysms. Brain aneurysms, which occur in 2-3% of the population, are balloon-like dilations of a blood vessel supplying the brain which may rupture and result in severe headaches, paralysis, coma and death. Currently, radiologists viewing Magnetic Resonance Imag ...

The broader impact/commercial impact of this Small Business Technology Transfer Research (STTR) project is to reduce the environmental impact of agricultural production while optimizing net income to producers. Over-application of nitrogen fertilizer contributes to groundwater contamination via nitrate-nitrogen leaching, and puts substantial financial burden on rural municipalities and private wel ...

The broader impact/commercial potential of this STTR project is to chemically recycle carbon dioxide, which would otherwise be released to the atmosphere, to useful fuels and products thus providing a closed loop for production and emissions for many common products. Virtually every industry uses petroleum and/or natural gas, either through transportation or plastics (e.g., packaging), and there i ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be to improve the safety testing of new drugs for approval by the FDA. By decreasing the time and costs associated with safety testing, the product will make all classes of new drugs safer, less expensive and available to patients sooner. All new drugs must demonstrate that they are safe. One com ...